Jacqueline D Keighron,Yuanmo Wang,Ann-Sofie Cans
Jacqueline D Keighron
Neuronal transmission relies on electrical signals and the transfer of chemical signals from one neuron to another. Chemical messages are transmitted from presynaptic neurons to neighboring neurons through the triggered fusion of neurotrans...
Lighting Up Live-Cell and In Vivo Central Carbon Metabolism with Genetically Encoded Fluorescent Sensors [0.03%]
用于活细胞和体内中枢碳代谢的遗传编码荧光传感器
Zhuo Zhang,Xiawei Cheng,Yuzheng Zhao et al.
Zhuo Zhang et al.
As the core component of cell metabolism, central carbon metabolism, consisting of glycolysis, the pentose phosphate pathway, and the tricarboxylic acid cycle converts nutrients into metabolic precursors for biomass and energy to sustain th...
Evolution of Analytical Sciences in the United States: A Historical Account [0.03%]
美国分析科学的历史发展ACCOUNT OF THE HISTORICAL DEVELOPMENT OF ANALYTICAL SCIENCES IN THE UNITED STATES
Gary D Christian
Gary D Christian
The current teaching and practice of analytical chemistry reflect the evolution of measurement science over time. Qualitative and quantitative measurements can be traced back to prebiblical times, have been important throughout human histor...
Anthony J Saviola,Fernanda Negrão,John R Yates rd
Anthony J Saviola
Technological advances in mass spectrometry have enabled the extensive identification, characterization, and quantification of proteins in any biological system. In disease processes proteins are often altered in response to external stimul...
Charles R Bupp,Mary J Wirth
Charles R Bupp
Protein separations have gained increasing interest over the past two decades owing to the dramatic growth of proteins as therapeutics and the completion of the Human Genome Project. About every decade, the field of protein high-performance...
Three-Dimensional Single Particle Tracking and Its Applications in Confined Environments [0.03%]
三维单粒子跟踪及其在受限环境中的应用
Yaning Zhong,Gufeng Wang
Yaning Zhong
Single particle tracking (SPT) has proven to be a powerful technique in studying molecular dynamics in complicated systems. We review its recent development, including three-dimensional (3D) SPT and its applications in probing nanostructure...
Brahim Achour,Zubida M Al-Majdoub,Amin Rostami-Hodjegan et al.
Brahim Achour et al.
Transporters are key to understanding how an individual will respond to a particular dose of a drug. Two patients with similar systemic concentrations may have quite different local concentrations of a drug at the required site. The transpo...
Emerging Standards and Analytical Science for Nanoenabled Medical Products [0.03%]
纳米技术医药产品的新兴标准和分析科学
Bryant C Nelson,Caterina Minelli,Shareen H Doak et al.
Bryant C Nelson et al.
Development and application of nanotechnology-enabled medical products, including drugs, devices, and in vitro diagnostics, are rapidly expanding in the global marketplace. In this review, the focus is on providing the reader with an introd...
Kexue Li,Junliang Liu,Chris R M Grovenor et al.
Kexue Li et al.
High-resolution SIMS analysis can be used to explore a wide range of problems in material science and engineering materials, especially when chemical imaging with good spatial resolution (50-100 nm) can be combined with efficient detection ...
Microfluidic Immunoassays for Time-Resolved Measurement of Protein Secretion from Single Cells [0.03%]
单细胞蛋白分泌的微流控免疫测定法
Mai Yamagishi,Osamu Ohara,Yoshitaka Shirasaki
Mai Yamagishi
Measurement of humoral factors secreted from cells has served as an indispensable method to monitor the states of a cell ensemble because humoral factors play crucial roles in cell-cell interaction and aptly reflect the states of individual...