High-Grade Acinic Cell Carcinoma of the Parotid with SYN2::PPARG Fusion [0.03%]
腮腺高分级导管细胞癌伴SYN2::PPARG融合突变病例报告
Andrii Puzyrenko,Prokopios P Argyris,Olga Pasternak-Wise et al.
Andrii Puzyrenko et al.
Case presentation: A 60-year-old man presented with a 3.4 cm, slow-growing, hypermetabolic, right parotid mass of 1-year duration with associated intermittent pain, facial swelling, and transient facial nerve paresthesia,...
Kevin Mijares,Diana Bell,Karen Schoedel et al.
Kevin Mijares et al.
Background: Adipocytic tumors of the head and neck are mostly benign, but laryngopharyngeal tumors are uncommon and poorly characterized. We compared the clinicopathologic profile of laryngopharyngeal liposarcomas (LP-LPS...
Cytoplasmic Granules in Granular Cell Tumor and Congenital Epulis: A Histochemical and Immunohistochemical Note [0.03%]
颗粒细胞肿瘤和先天性牙龈瘤胞浆颗粒的组织化学和免疫组织化学观察注意点
Aadithya B Urs,Revathi Krishna,Lama Malik et al.
Aadithya B Urs et al.
Background: Cytoplasmic granularity is a distinctive histomorphologic feature observed in several oral lesions and is commonly attributed to the accumulation of lysosomes or other intracellular organelles. Granular cell t...
Expanding the Histologic Spectrum of Human Papillomavirus (HPV)-Associated Oropharyngeal Carcinoma: A Retrospective Study of 379 Cases Focusing on Classification, Histologic Features, and their Prognostic Significance [0.03%]
扩大人类乳头瘤病毒(HPV)相关口咽癌的组织学谱系：对379例患者进行分类、组织病理特征及预后意义的回顾性研究
Ronald Ghossein,Ahmed Lazim,Snjezana Dogan et al.
Ronald Ghossein et al.
Background: The WHO classification includes squamous cell carcinoma (SCC) and neuroendocrine carcinoma as two histotypes of HPV-associated oropharyngeal carcinoma (HPV + OPC). Among SCC, the recognized subtypes include no...
FoxP3+ Cells and PNAd+ Tumour-Associated High Endothelial Venules: Synergistic Prognostic Markers in Oral Tongue Squamous Cell Carcinoma [0.03%]
口腔舌鳞状细胞癌中FoxP3+细胞和PNAd+肿瘤相关高内皮微静脉：协同预后标志物
Ibrahim Afolabi Abdulsalam,Kjersti Sellæg,Faith O Benebo et al.
Ibrahim Afolabi Abdulsalam et al.
Purpose: Oral tongue squamous cell carcinoma (OTSCC) features significant immune cell infiltration. In head and neck SCC, peripheral node addressin (PNAd) + tumour-associated high endothelial venules (TA-HEVs) and CD163+ ...
Characterization of CD8 + and CD68 + Microenvironment and PDL1 Expression in HPV-related Multiphenotypic Sinonasal Carcinoma [0.03%]
HPV相关多表型鼻窦癌的CD8+和CD68+微环境及PDL1表达特征分析
João Epaminondas Silva de Araújo,João Paulo Gonçalves de Paiva,Igor Lima Fernandes et al.
João Epaminondas Silva de Araújo et al.
Aim: To characterize the expression of CD8 + T cells, CD68 + macrophages, and PDL1 in HPV-related multiphenotypic sinonasal carcinoma (HMSC) and evaluate their correlations with clinical outcomes. ...
International Consensus Guidelines for Diagnostic Criteria and Checklist for Future Studies for Minimally Invasive Carcinoma ex Pleomorphic Adenoma: An HN CLEAR Initiative [0.03%]
微创乳头状癌诊断标准的国际共识及未来研究检查表（HN CLEAR倡议）
Beth M Beadle,Nazim Benzerdjeb,Junhun Cho et al.
Beth M Beadle et al.
A variety of factors, including the extent of invasion, determine the clinical outcome in patients with carcinoma ex pleomorphic adenoma (Ca ex PA). A Head and Neck Consensus Language for Ease of Reproducibility (HN CLEAR) Steering Committe...
Integrated Clinical, Histopathological, and Inflammatory Parameters for Predicting Malignant Transformation in High-Risk Oral Potentially Malignant Disorders: A Prospective Study [0.03%]
高危口腔癌前病变恶性转化的临床、病理和炎症参数的整合预测：一项前瞻性研究
Rinal Chavda,Swapnil U Rane,Neha Mittal et al.
Rinal Chavda et al.
Background: Oral epithelial dysplasia (OED) is a recognised precursor of oral squamous cell carcinoma (OSCC). Previous studies have identified specific OED features that are significantly associated with recurrence and ma...
Proceedings of the 2026 North American Society of Head and Neck Pathology Companion Meeting, San Antonio, TX, March 22, 2026: It's a Trap! Pitfalls in Thyroid Pathology: Mets or Not Mets? [0.03%]
2026年北美头颈部病理学协会会议（美国德克萨斯州圣安东尼奥，2026年3月22日）：陷阱！甲状腺病理诊断中的陷阱：是转移性肿瘤吗？
Yu-Che Chuang,Jen-Fan Hang
Yu-Che Chuang
Background: Similar to other head and neck organs, thyroid pathology encompasses a broad spectrum of diagnostic entities. The significant overlap in architectural or cytological features across these entities presents a u...
Sinonasal Nonkeratinizing Squamous Cell Carcinoma with Synchronous Presence of HPV-High Risk and MKRN1::BRAF Fusion [0.03%]
伴有高危HPV和MKRN1::BRAF融合的鼻窦非角化鳞状细胞癌
Diana Bell,Eric W Wang,Garret Choby et al.
Diana Bell et al.
An increased understanding of molecular alterations over the last decade has also impacted the landscape of sinonasal squamous cell carcinoma (SNSCC). In addition to traditional SCC risk factors (e.g. smoking) and high-risk HPV (HR- HPV), o...