An Institutional Experience of Core Needle Biopsy with Cooperative Implementation by Pathologists and Head and Neck Oncologists in Salivary Gland Carcinoma [0.03%]
头颈肿瘤学家与病理学家合作开展腮腺癌空心针穿刺活检的机构经验分析
Kenya Kobayashi,Seiichi Yoshimoto,Go Omura et al.
Kenya Kobayashi et al.
Purpose: A major problem in establishing treatment strategies for salivary gland carcinomas is the difficulty of preoperative histologic subtyping. Core needle biopsy (CNB) allows the collection of a small, intact specime...
Beyond the Microscope: Pathology Education and Leadership - Choosing a Fellowship [0.03%]
显微镜之外：病理学教育与领导力——选择一项奖学金项目
Karleen Meiklejohn,Maria Martinez-Lage
Karleen Meiklejohn
Targeted RNA Sequencing of Head and Neck Adenoid Cystic Carcinoma Reveals SEC16A::NOTCH1 Fusion and MET Exon 14 Skipping as Potentially Actionable Alterations [0.03%]
头颈部腺样囊性癌靶向RNA测序发现SEC16A::NOTCH1融合和MET第14外显子跳跃为潜在可操作改变
Ying-Hsia Chu,Bin Xu,Purvil Sukhadia et al.
Ying-Hsia Chu et al.
Purpose: Adenoid cystic carcinoma (AdCC) of the head and neck harbors MYB/MYBL1::NFIB fusions in around 60% of cases, with unfavorable long-term survival due to frequent recurrences and metastases, currently lacking effec...
Malignant Salivary Gland Neoplasm of the Tongue Base with EWSR1::BEND2 Fusion: An Unusual Case with Literature Review [0.03%]
舌根部恶性腮腺肿瘤伴EWSR1::BEND2融合——附1例分析及文献复习
Yuan-Dong Zhang,Jiang-Jie Sun,Shao-Yan Xi et al.
Yuan-Dong Zhang et al.
Purpose: Salivary gland malignancies may have overlapping architectural patterns, tumor morphology, and immunohistochemical phenotypes, presenting challenges in precise classification. Molecular phenotyping has become qui...
Thomas N Helm,Sanica Bhele,Julie C Fanburg-Smith
Thomas N Helm
Eosinophils are often encountered in the stroma and peritumoral microenvironment of squamous cell carcinomas. Because eosinophils are readily identified on routine hematoxylin and eosin stained sections, researchers have explored multiple w...
NanoString nCounter-Based Assay for Detection of Fusion-Associated Salivary Gland Tumors [0.03%]
用于检测融合基因相关涎腺肿瘤的纳米环计数法检测方法
Angela Goytain,Tony L Ng
Angela Goytain
Purpose: Salivary gland tumors include numerous subtypes that vary from benign to highly aggressive, with many showing overlapping histopathological features that can make diagnosis challenging. Most subtypes express driv...
Deep Convolutional Neural Network for Accurate Classification of Myofibroblastic Lesions on Patch-Based Images [0.03%]
基于补丁图像的肌成纤维细胞病变准确分类的深度卷积神经网络
Daniela Giraldo-Roldán,Giovanna Calabrese Dos Santos,Anna Luíza Damaceno Araújo et al.
Daniela Giraldo-Roldán et al.
Objective: This study aimed to implement and evaluate a Deep Convolutional Neural Network for classifying myofibroblastic lesions into benign and malignant categories based on patch-based images. ...
Comparative Analysis of MYB Expression by Immunohistochemistry and RNA Sequencing in Clinical Gene Fusion Detection in Adenoid Cystic Carcinoma [0.03%]
腺样囊性癌临床基因融合检测中MYB表达的免疫组化与RNA测序对比分析
Adam S Fisch,Alexander A Farahani,Julia Thierauf et al.
Adam S Fisch et al.
Purpose: MYB has been shown to play a central role in oncogenesis in a majority of adenoid cystic carcinomas (ACC). Testing for MYB expression via immunohistochemistry (IHC) or testing for the MYB gene fusion by next-gene...
Comparative Study
Head and neck pathology. 2024 Oct 26;18(1):114. DOI:10.1007/s12105-024-01719-1 2024
Squamous Cell Carcinoma Arising in a Squamous Odontogenic Tumor of the Maxilla: Case Report and Review of the Literature [0.03%]
上颌鳞状牙源性肿瘤继发鳞状细胞癌一例并文献复习
Fawaz Alotaibi,Yousef Alshamrani,Harish Tummala et al.
Fawaz Alotaibi et al.
Squamous odontogenic tumor (SOT) is an exceedingly rare, benign epithelial odontogenic tumor showing squamous differentiation. It is composed of variably sized and shaped islands of cytologically bland, mature squamous epithelium within a f...
Alessandra Acioli Landim,Mariela Peralta-Mamani,Guilherme Acioli Landim et al.
Alessandra Acioli Landim et al.
Purpose: This PRISMA-guided and PROSPERO-registered systematic review aimed to summarise the current knowledge on the characteristics (clinical, radiographic, and histopathological) and treatment options for segmental odo...