A Multimodal Predictive Model for Chronic Kidney Disease and Its Association With Vascular Complications in Patients With Type 2 Diabetes: Model Development and Validation Study in South Korea and the U.K [0.03%]
针对2型糖尿病患者慢性肾脏病及其与血管并发症关联的多模态预测模型的研发和验证研究：韩国和英国的研究
Jaehyeong Cho,Selin Woo,Seung Ha Hwang et al.
Jaehyeong Cho et al.
Objective: To develop a multimodal model to predict chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM), given the limited research on this integrative approach. ...
Prediction of Weight Loss and Regain Based on Multiomic and Phenotypic Features: Results From a Calorie-Restricted Feeding Trial [0.03%]
基于多组学和表型特征的体重减轻和反弹预测：来自一项热量限制喂养试验的结果
Lin Li,Ruyi Li,Zixin Qiu et al.
Lin Li et al.
Objective: To identify baseline multiomic and phenotypic predictors and develop prediction models for weight and body composition loss and regain in the Low-Carbohydrate Diet and Time-Restricted Eating (LEAN-TIME) trial. ...
High Prevalence of Prediabetes Among Asian and Pacific Islander Adolescents With Overweight or Obesity in a Primary Care Population [0.03%]
在初级保健人群中，超重或肥胖的亚洲及太平洋岛青少年中糖尿病前期患病率高
Adrian Matias Bacong,Veronica Njuguna,Jeanne Darbinian et al.
Adrian Matias Bacong et al.
Objective: To compare prediabetes prevalence among disaggregated U.S. Asian and Pacific Islander (Asian/PI) adolescents with non-Hispanic White (NHW) adolescents with overweight or obesity in a primary care population. ...
Impaired Rest-Activity Rhythm Characteristics Predict Higher Risk of Incident Type 2 Diabetes in UK Biobank Participants [0.03%]
英国生物样本库参与者中受损的休息活动节律特征预示更高的2型糖尿病发病风险
Chris Ho Ching Yeung,Alison K Wright,Daniel P Windred et al.
Chris Ho Ching Yeung et al.
Objective: Circadian rhythms play a key role in metabolic health. Rest-activity rhythms, which are in part driven by circadian rhythms, may be associated with diabetes risk. There is a need for large prospective studies t...
Glucagon-Like Peptide 1 Receptor Agonists and the Risk of Emergency Department Visits and Hospitalization in Patients With Chronic Kidney Disease [0.03%]
胃泌素释放肽受体激动剂与慢性肾脏病患者急诊和住院风险的关系
Kevin Yau,Joel G Ray,Nivethika Jeyakumar et al.
Kevin Yau et al.
Objective: The aim of this study was to evaluate the effect of glucagon-like peptide 1 receptor agonist (GLP-1RA) versus dipeptidyl peptidase 4 inhibitor (DPP4i) initiation on emergency department (ED) visits and all-caus...
Differential Effect of GLP-1 Receptor Agonists and SGLT2 Inhibitors on Lower-Extremity Amputation Outcomes in Type 2 Diabetes: A Nationwide Retrospective Cohort Study [0.03%]
二甲双胍治疗糖尿病的肾脏不良事件：倾向评分加权全国性队列研究
Alexander T Hong,Ivan Y Luu,Forest Lin et al.
Alexander T Hong et al.
Objective: To compare the risk of lower-extremity amputations (LEAs) between new users of glucagon-like peptide 1 receptor agonists (GLP-1RAs) versus sodium-glucose cotransporter 2 inhibitors (SGLT2is). ...
Diabetes-Related Distress and Glycemic Dysregulation in Everyday Life With Type 1 Diabetes: Which Comes First? [0.03%]
1型糖尿病患者日常生活中的血糖失调与糖尿病相关的精神压力：哪个是首要因素？
Jeffrey S Gonzalez,Claire J Hoogendoorn,Raymond Hernandez et al.
Jeffrey S Gonzalez et al.
Objective: In an observational study, we paired ecological momentary assessment (EMA) and continuous glucose monitoring (CGM) to examine lagged effects of glycemic regulation on diabetes-related distress (DD), and vice ve...
Inadequately Controlled Type 2 Diabetes and Hypercortisolism: Improved Glycemia With Mifepristone Treatment [0.03%]
二型糖尿病控制不佳和高皮质醇症:mifepristone治疗可改善血糖水平
Ralph A DeFronzo,Vivian Fonseca,Vanita R Aroda et al.
Ralph A DeFronzo et al.
Objective: In many individuals, type 2 diabetes (T2D) remains poorly controlled despite taking multiple glucose-lowering therapies. Several studies have demonstrated that endogenous hypercortisolism is prevalent among the...
Barbara H Braffett,Tore Julsrud Berg,Malin Zimmerman et al.
Barbara H Braffett et al.
Upper-limb complications (ULCs) in diabetes, affecting joints, tendons, muscles, connective tissue, nerves, and skin, are underrecognized but prevalent conditions in type 1 and type 2 diabetes. Advances in diabetes care have extended life e...
Cardiovascular Outcomes and Efficacy of the PCSK9 Inhibitor Evolocumab in Individuals With Type 1 Diabetes: Insights From the FOURIER Trial [0.03%]
在1型糖尿病患者中PCSK9抑制剂依洛尤单抗的心血管结局和疗效：FOURIER研究启示
Yu Mi Kang,Robert P Giugliano,Xinhui Ran et al.
Yu Mi Kang et al.
Objective: To evaluate the clinical efficacy of intensive LDL cholesterol (LDL-C) lowering in type 1 diabetes mellitus (T1DM). Research design and methods...