Exploration of tongue dorsum sampling to support clinical diagnosis of leprosy patients in the Comoros: A cross-sectional study [0.03%]
一项在科摩罗进行的舌背取样用于支持麻风病患者临床诊断的研究：横断面研究
Lena Krausser,Maren Van Nieuwenhove,Nissad Attoumane et al.
Lena Krausser et al.
Background: The accuracy of the WHO-endorsed clinical leprosy diagnosis depends on the expertise of health care workers. For molecular confirmation of clinically diagnosed patients, skin biopsies have the highest sensitiv...
Exploring the status of brucellosis in pregnant women presented with febrile illness at different healthcare facilities of Vehari and Lodhran zones of Pakistan [0.03%]
巴基斯坦vehari和lodhran地区不同医疗机构就诊的发热孕妇布鲁氏菌病患病状况调查
Syed Muhammad Tauseef Shafqat,Mian Muhammad Awais,Ulas Acaroz et al.
Syed Muhammad Tauseef Shafqat et al.
Background: Brucellosis is an important zoonotic disease which causes stillbirth and abortion in pregnant women. It remains undiagnosed due to nonspecific symptoms like febrility, a very common ailment sign. Accordingly, ...
Fixed-dose ivermectin for Mass Drug Administration: Is it time to leave the dose pole behind? Insights from an Individual Participant Data Meta-Analysis [0.03%]
基于个体参与者数据的 meta 分析：服药剂量已固定，群体药物服用还需量体裁衣吗？
Adriana Echazu,Daniela Bonanno,Pedro Emanuel Fleitas et al.
Adriana Echazu et al.
Background: Ivermectin (IVM) is widely used in mass drug administration (MDA) programs for the control of neglected tropical diseases (NTDs). Current regimens rely on weight- or height-based dosing, which lead to operativ...
Chikungunya virus in Thailand (2020-2023): Epidemiology, clinical features, and genomic insights [0.03%]
泰国的奇昆古尼亚病毒（2020-2023）：流行病学、临床特征和基因组见解
Sarawut Khongwichit,Watchaporn Chuchaona,Sumeth Korkong et al.
Sarawut Khongwichit et al.
Chikungunya virus (CHIKV) caused significant outbreaks in Thailand during 2008-2009 and 2018-2020. Despite the COVID-19 pandemic, CHIKV continued to circulate; however, data on its epidemiological, clinical, and genetic characteristics duri...
Disability and quality of life assessment using WHODAS-12 items 2.0 and EQ-5D-5L in a rural area endemic for loiasis in the Republic of Congo: A population-based cross-sectional study (the MorLo project) [0.03%]
利用WHODAS-12和EQ-5D-5L评估刚果共和国洛亚丝虫病地方性农村地区居民的残疾状况和生活质量：一项基于人群的横断面研究（莫尔洛项目）
Marlhand C Hemilembolo,Jérémy T Campillo,Valentin Dupasquier et al.
Marlhand C Hemilembolo et al.
Background: Loa loa filariasis, a parasitic infection endemic to Central Africa, is a common cause of medical consultation in this region. Methods: ...
Unexplained subcutaneous swelling: Keep echinococcosis in mind! Report of two primary extrahepatic subcutaneous echinococcosis cases and literature review [0.03%]
不明皮下肿物莫忘细粒棘球蚴病！2例原发性肝外皮下细粒棘球蚴病报告及文献复习
Louis Bohard,Eléonore Brumpt,Noémie Tissot et al.
Louis Bohard et al.
Alveolar and cystic echinococcoses (AE and CE) are parasitic zoonoses, mainly affecting the liver. Primary extrahepatic localizations remain rare and are difficult to diagnose. We report two cases of primary subcutaneous echinococcosis and ...
Roles of tick-cofeeding hedgehogs in the natural transmission of spotted fever group Rickettsia [0.03%]
刺叮共饲猬形刺螨在斑点热群立克次氏体自然传播中的作用
Haiming Yi,Weilin Huang,Changqiang Zhu et al.
Haiming Yi et al.
Tick-borne spotted fever group Rickettsia (SFGR) poses a significant threat to public health worldwide. The cofeeding behavior of ticks attaching host animals, such as hedgehogs, has been identified as a potential mechanism for transmitting...
Whole genome sequencing of Yersinia pestis isolates from Central Asian natural plague foci revealed the role of adaptation to different hosts and environmental conditions in shaping specific genotypes [0.03%]
中央亚自然鼠疫菌系全基因组测序表明了不同宿主和环境条件适应在形成特定菌株中所起的作用
Aigul A Abdirassilova,Duman T Yessimseit,Altynai K Kassenova et al.
Aigul A Abdirassilova et al.
The genetic diversity and biovar classification of Yersinia isolates from Central Asia were investigated using whole-genome sequencing. In total, 98 isolates from natural plague foci were sequenced using the MiSeq platform. Computational pi...
Development and proof of concept evaluation for a low resource compatible Chikungunya virus diagnostic [0.03%]
针对恰昆古尼亚热病毒诊断的低资源兼容型检测方法的研发及其概念验证评估
Rickyle Balea,Alberto A Amarilla,Jody Hobson-Peters et al.
Rickyle Balea et al.
Chikungunya virus (CHIKV) is a positive sense RNA Alphavirus that continuous to pose major public health threats throughput the world. CHIKV is primarily transmitted via the Aedes genus mosquito, however, has also exhibited transmission rou...
Computational and experimental exploration of statin and statin-like compounds as potential treatment of schistosomiasis [0.03%]
计算和实验探索他汀类和类似他汀类化合物作为血吸虫病潜在治疗药物的可能性
Kehinde F Paul-Odeniran,Paul O Odeniran,Cécile Häberli et al.
Kehinde F Paul-Odeniran et al.
Schistosomiasis remains a global health challenge, affecting over 240 million people each year. Current treatment options, including praziquantel, are limited by their inability to target immature schistosomula and growing concerns around d...