Pre-clinical mouse models of human prostate cancer and their utility in drug discovery [0.03%]
人前列腺癌的非临床小鼠模型及其在药物发现中的应用价值
Serk In Park,Sun Jin Kim,Laurie K McCauley et al.
Serk In Park et al.
In vivo animal experiments are essential to current prostate cancer research, and are particularly critical to studying interactions between tumor cells and their microenvironment. Numerous pre-clinical animal models of prostate cancer are ...
Xenograft and Transgenic Mouse Models of Epithelial Ovarian Cancer and Non Invasive Imaging Modalities to Monitor Ovarian Tumor Growth In situ -Applications in Evaluating Novel Therapeutic Agents [0.03%]
异种移植和转基因小鼠模型在上皮性卵巢癌中的应用及非侵入式成像模式对卵巢肿瘤原位生长的监测-及其在评估新型治疗药物方面的应用
Denise C Connolly,Harvey H Hensley
Denise C Connolly
Epithelial ovarian cancer (EOC) is the most commonly fatal gynecologic malignancy in developed countries. Most EOC patients are diagnosed at advanced stage when disease has spread beyond the ovary. While many patients initially respond to s...
John A Beutler
John A Beutler
Natural products have contributed to the development of many drugs for diverse indications. While most U.S. pharmaceutical companies have reduced or eliminated their in-house natural product groups, new paradigms and new enterprises have ev...