Intravital Imaging of Neuroimmune Interactions Through a Thinned Skull [0.03%]
通过薄化 skull 进行神经免疫相互作用的活体成像
Monica Manglani,Dorian B McGavern
Monica Manglani
Innate and adaptive immune interactions within the central nervous system (CNS) and surrounding meninges contribute significantly to neural homeostasis as well as a variety of different neurological disorders. Two-photon laser scanning micr...
John Wonderlich,Gene Shearer,Alexandra Livingstone et al.
John Wonderlich et al.
Cytotoxic T cells (CTLs) are important immune effector cells in the adaptive immune response. It has been well documented that CTLs are important in host immune responses to viral and bacterial intracellular pathogens, tumors, and transplan...
Thy1-YFP-H Mice and the Parallel Rod Floor Test to Evaluate Short- and Long-Term Progression of Traumatic Brain Injury [0.03%]
Thy1-YFP-H小鼠和并行杆地板测试评估创伤性脑损伤的短期和长期进展
Monique Richter,María Luciana Negro-Demontel,Daniela Blanco-Ocampo et al.
Monique Richter et al.
Traumatic brain injury (TBI) is a leading cause of death and disability and is a risk factor for the later development of neuropsychiatric disorders and neurodegenerative diseases. Many models of TBI have been developed, but their further r...
Cédric Bosteels,Bart N Lambrecht,Hamida Hammad
Cédric Bosteels
The lungs are continuously exposed to environmental threats, requiring an adequate and stringent immune response of a heterogeneous set of effector cells. Dendritic cells (DCs) form a dense network in the respiratory mucosa and act as the c...
Liposome Preparation for the Analysis of Lipid-Receptor Interaction and Efferocytosis [0.03%]
用于分析脂质受体相互作用和凋亡细胞吞噬的脂osomes制备方法
Oliver H Voss,Ha-Na Lee,Linjie Tian et al.
Oliver H Voss et al.
Efficient phagocytosis of apoptotic cells (efferocytosis) is essential for immune homeostasis. Phospholipids exposed on the surface of apoptotic cells, such as phosphatidylserine, supply important "eat-me" signals. Liposomes are lipid bilay...
Flow Cytometry: An Overview [0.03%]
流式细胞术概述
Katherine M McKinnon
Katherine M McKinnon
Flow cytometry is a technology that provides rapid multi-parametric analysis of single cells in solution. Flow cytometers utilize lasers as light sources to produce both scattered and fluorescent light signals that are read by detectors suc...
Ken Kamata,Tomohiro Watanabe,Kosuke Minaga et al.
Ken Kamata et al.
Autoimmune pancreatitis (AIP) is a chronic fibro-inflammatory disorder of the pancreas. However, extensive clinico-pathological analyses have revealed that AIP is, in reality, a pancreatic manifestation of a newly described systemic disease...
Hadar Reichman,Perri Rozenberg,Ariel Munitz
Hadar Reichman
Eosinophils are bone marrow-derived cells that differentiate in the bone marrow and migrate into the peripheral blood primarily under the regulation of interleukin (IL)-5. Eosinophil levels in the blood are relatively low. However, under st...
Zbigniew Darzynkiewicz,Xuan Huang,Hong Zhao
Zbigniew Darzynkiewicz
Cellular DNA content can be measured by flow cytometry with the aim of : (1) revealing cell distribution within the major phases of the cell cycle, (2) estimating frequency of apoptotic cells with fractional DNA content, and/or (3) disclosi...
Thomas Myles Ashhurst,Adrian Lloyd Smith,Nicholas Jonathan Cole King
Thomas Myles Ashhurst
The immune system consists of a complex network of cells, all expressing a wide range of surface and/or intracellular proteins. Using flow cytometry, these cells can be analyzed by labeling with fluorophore-conjugated antibodies. The recent...