Steven J Marygold,Giulia Antonazzo,Helen Attrill et al.
Steven J Marygold et al.
FlyBase (flybase.org) is the primary online database of genetic, genomic, and functional information about Drosophila species, with a major focus on the model organism Drosophila melanogaster. The long and rich history of Drosophila researc...
The Search Engine for Multi-Proteoform Complexes: An Online Tool for the Identification and Stoichiometry Determination of Protein Complexes [0.03%]
多蛋白复合物的搜索引擎：识别和确定蛋白质复合物的组分及比例的在线工具
Owen S Skinner,Luis F Schachner,Neil L Kelleher
Owen S Skinner
Recent advances in top-down mass spectrometry using native electrospray now enable the analysis of intact protein complexes with relatively small sample amounts in an untargeted mode. Here, we describe how to characterize both homo- and het...
cgpCaVEManWrapper: Simple Execution of CaVEMan in Order to Detect Somatic Single Nucleotide Variants in NGS Data [0.03%]
CGP CaVEManWrapper：简单执行CaVEMan以检测NGS数据中的体细胞单核苷酸变异
David Jones,Keiran M Raine,Helen Davies et al.
David Jones et al.
CaVEMan is an expectation maximization-based somatic substitution-detection algorithm that is written in C. The algorithm analyzes sequence data from a test sample, such as a tumor relative to a reference normal sample from the same patient...
Using MetaboAnalyst 3.0 for Comprehensive Metabolomics Data Analysis [0.03%]
利用MetaboAnalyst 3.0进行全面代谢组数据解析
Jianguo Xia,David S Wishart
Jianguo Xia
MetaboAnalyst (http://www.metaboanalyst.ca) is a comprehensive Web application for metabolomic data analysis and interpretation. MetaboAnalyst handles most of the common metabolomic data types from most kinds of metabolomics platforms (MS a...
Tempest: Accelerated MS/MS Database Search Software for Heterogeneous Computing Platforms [0.03%]
风暴算法：异构平台上的快速MS/MS数据库搜索软件
Mark E Adamo,Scott A Gerber
Mark E Adamo
MS/MS database search algorithms derive a set of candidate peptide sequences from in silico digest of a protein sequence database, and compute theoretical fragmentation patterns to match these candidates against observed MS/MS spectra. The ...
Alisha Parveen,Norbert Gretz,Harsh Dweep
Alisha Parveen
miRWalk2.0 (http://zmf.umm.uni-heidelberg.de/mirwalk2) is a freely accessible, regularly updated comprehensive archive supplying the largest available collection of predicted and experimentally verified miRNA-target interactions, with vario...
DIANA-TarBase and DIANA Suite Tools: Studying Experimentally Supported microRNA Targets [0.03%]
DIANA-TarBase和DIANA套装工具：研究实验支持的microRNA作用靶点
Maria D Paraskevopoulou,Ioannis S Vlachos,Artemis G Hatzigeorgiou
Maria D Paraskevopoulou
microRNAs (miRNAs) are short non-coding RNAs (∼22 nts) present in animals, plants, and viruses. They are considered central post-transcriptional regulators of gene expression and are key components in a great number of physiological and pa...
Luigi Di Costanzo,Sutapa Ghosh,Christine Zardecki et al.
Luigi Di Costanzo et al.
The Protein Data Bank (PDB) archive is the worldwide repository of experimentally determined three-dimensional structures of large biological molecules found in all three kingdoms of life. Atomic-level structures of these proteins, nucleic ...
Inference of Episodic Changes in Natural Selection Acting on Protein Coding Sequences via CODEML [0.03%]
利用CODEML推断作用于蛋白质编码序列的自然选择的阶段性变化
Joseph P Bielawski,Jennifer L Baker,Joseph Mingrone
Joseph P Bielawski
This unit provides protocols for using the CODEML program from the PAML package to make inferences about episodic natural selection in protein-coding sequences. The protocols cover inference tasks such as maximum likelihood estimation of se...
Benjamin Webb,Andrej Sali
Benjamin Webb
Comparative protein structure modeling predicts the three-dimensional structure of a given protein sequence (target) based primarily on its alignment to one or more proteins of known structure (templates). The prediction process consists of...