Peter Beerli,Somayeh Mashayekhi,Marjan Sadeghi et al.
Peter Beerli et al.
Many evolutionary biologists collect genetic data from natural populations and then need to investigate the relationship among these populations to compare different biogeographic hypotheses. MIGRATE, a useful tool for exploring relationshi...
Using INTERSPIA to Explore the Dynamics of Protein-Protein Interactions Among Multiple Species [0.03%]
运用INTERSPIA探索多物种间蛋白质相互作用的动态变化规律
Daehong Kwon,Daehwan Lee,Juyeon Kim et al.
Daehong Kwon et al.
INTER-Species Protein Interaction Analysis (INTERSPIA) is a web application for identifying diverse patterns of protein-protein interactions (PPIs) in different species. Given a set of proteins of interest to the user, INTERSPIA first disco...
Jennifer Jou,Idan Gabdank,Yunhai Luo et al.
Jennifer Jou et al.
The Encyclopedia of DNA Elements (ENCODE) web portal hosts genomic data generated by the ENCODE Consortium, Genomics of Gene Regulation, The NIH Roadmap Epigenomics Consortium, and the modENCODE and modERN projects. The goal of the ENCODE p...
Using Mothur to Determine Bacterial Community Composition and Structure in 16S Ribosomal RNA Datasets [0.03%]
基于16S核糖体RNA数据集确定细菌群落组成和结构的mothur分析方法
Sruthi Chappidi,Erika C Villa,Brandi L Cantarel
Sruthi Chappidi
The 16S ribosomal RNA (rRNA) gene is one of the scaffolding molecules of the prokaryotic ribosome. Because this gene is slow to evolve and has very well conserved regions, this gene is used to reconstruct phylogenies in prokaryotes. Univers...
Predicting Sequence Features, Function, and Structure of Proteins Using MESSA [0.03%]
基于MESSA预测蛋白质的序列特征、功能和结构
Archana S Bhat,Nick V Grishin
Archana S Bhat
MEta-Server for protein Sequence Analysis (MESSA) is a tool that facilitates widespread protein sequence analysis by gathering structural (local sequence properties and three-dimensional structure) and functional (annotations from SWISS-PRO...
Using MARRVEL v1.2 for Bioinformatics Analysis of Human Genes and Variant Pathogenicity [0.03%]
使用MARRVEL v1.2进行人类基因和变异致病性生物信息学分析
Julia Wang,Dongxue Mao,Fatima Fazal et al.
Julia Wang et al.
One of the greatest challenges in the bioinformatic analysis of human sequencing data is identifying which variants are pathogenic. Numerous databases and tools have been generated to address this difficulty. However, these many useful data...
Ploidy- and Purity-Adjusted Allele-Specific DNA Analysis Using CLONETv2 [0.03%]
基于CLONETv2的倍性及纯度修正的单体型分型分析方法
Davide Prandi,Francesca Demichelis
Davide Prandi
High-throughput DNA sequencing technology provides base-level and statistically rich information about the genomic content of a sample. In the contexts of cancer research and precision oncology, thousands of genomes from paired tumor and ma...
Community Curation and Expert Curation of Human Long Noncoding RNAs with LncRNAWiki and LncBook [0.03%]
LncRNAWiki和LncBook：社区协作与专家评议相集合的人类长链非编码RNA数据库
Lina Ma,Jiabao Cao,Lin Liu et al.
Lina Ma et al.
In recent years, the number of human long noncoding RNAs (lncRNAs) that have been identified has increased exponentially. However, these lncRNAs are poorly annotated compared to protein-coding genes, posing great challenges for a better und...
R Tutorial: Detection of Differentially Interacting Chromatin Regions From Multiple Hi-C Datasets [0.03%]
染色质相互作用图谱的高通量Hi-C数据分析教程：用于识别多个Hi-C数据集中的差异性互作区域
John C Stansfield,Duc Tran,Tin Nguyen et al.
John C Stansfield et al.
The three-dimensional (3D) interactions of chromatin regulate cell-type-specific gene expression, recombination, X-chromosome inactivation, and many other genomic processes. High-throughput chromatin conformation capture (Hi-C) technologies...
Claudio Bassot,David Menendez Hurtado,Arne Elofsson
Claudio Bassot
In spite of the fact that there has been a significant increase in the number of solved protein structures, structural information is missing for many proteins. Although structural information is codified in the amino acid sequence, computa...