David S Wishart
David S Wishart
Cheminformatics is a relatively new field of information technology that focuses on the collection, storage, analysis, and manipulation of chemical data. The chemical data of interest typically includes information on small molecule formula...
Using ProSight PTM and related tools for targeted protein identification and characterization with high mass accuracy tandem MS data [0.03%]
基于高精度串联质谱数据的ProSight PTM及其相关工具在蛋白质鉴定及修饰位点表征中的应用
Richard D Leduc,Neil L Kelleher
Richard D Leduc
ProSight PTM v2.0, neuroProSight, and the Sequence Gazer allow the identification and characterization of proteins from high mass accuracy tandem mass spectrometric data of intact proteins and large peptides. Input data consists of one or m...
Installation and use of the Computational Proteomics Analysis System (CPAS) [0.03%]
计算蛋白质组学分析系统（CPAS）的安装和使用
Tamra Myers,Wendy Law,Jimmy K Eng et al.
Tamra Myers et al.
The community of proteomic researchers has been generating openly available software infrastructure for systematic proteomic data analyses and data management for the past several years. The Computational Proteomics Analysis System (CPAS) i...
Validation of tandem mass spectrometry database search results using DTASelect [0.03%]
用DTASelect验证串联质谱数据库搜索结果
Daniel Cociorva,David L Tabb,John R Yates
Daniel Cociorva
DTASelect provides a means by which complex SEQUEST results can be filtered, organized, and viewed. A single sample may produce tens of thousands of tandem mass spectra. Manually perusing and selecting SEQUEST matches among such a mass of d...
Stefan Washietl,Ivo L Hofacker
Stefan Washietl
The functions of many noncoding RNAs and cis-acting regulatory elements of mRNAs depend on a defined RNA secondary structure. RNAz predicts such functional RNA structures on the basis of thermodynamic stability and evolutionary conservation...
Melissa de la Bastide,W Richard McCombie
Melissa de la Bastide
The PHRAP assembly program provides rapid comparison, alignment, and assembly of large sets of DNA sequences. PHRAP compares sequences by searching for pairs of perfectly matching "words" or sequence regions that meet certain criteria. If a...
James Taylor,Ian Schenck,Dan Blankenberg et al.
James Taylor et al.
While most experimental biologists know where to download genomic data, few have a concrete plan on how to analyze it. This situation can be corrected by: (1) providing unified portals serving genomic data and (2) building Web applications ...
Tyra G Wolfsberg
Tyra G Wolfsberg
This unit includes an introduction to the Map Viewer, which describes how to perform a simple text-based search of genome annotations to view the genomic context of a gene, navigate along a chromosome, zoom in and out, and change the displa...
The UCSC Genome Browser [0.03%]
UCSC基因组浏览器
Donna Karolchik,Angie S Hinrichs,W James Kent
Donna Karolchik
The University of California Santa Cruz (UCSC) Genome Browser (genome.ucsc.edu) is a popular Web-based tool for quickly displaying a requested portion of a genome at any scale, accompanied by a series of aligned annotation "tracks". The ann...
Xosé M Fernández-Suárez,Michael K Schuster
Xosé M Fernández-Suárez
The Ensembl genome Web browser (http://www.ensembl.org) provides a comprehensive source of automatic annotation of the human genome sequence (as well as other species of biomedical interest), with confirmed gene predictions that have been i...