Data storage and analysis in ArrayExpress and Expression Profiler [0.03%]
ArrayExpress和Expression Atlas中的数据存储及分析方法
Gabriella Rustici,Misha Kapushesky,Nikolay Kolesnikov et al.
Gabriella Rustici et al.
ArrayExpress at the European Bioinformatics Institute is a public database for MIAME-compliant microarray and transcriptomics data. It consists of two parts: the ArrayExpress Repository, which is a public archive of microarray data, and the...
Penny Coggill,Robert D Finn,Alex Bateman
Penny Coggill
Pfam is a database of protein domain families, with each family represented by multiple sequence alignments and profile hidden Markov models (HMMs). In addition, each family has associated annotation, literature references, and links to oth...
PharmGKB: an integrated resource of pharmacogenomic data and knowledge [0.03%]
药理基因组学知识库（PharmGKB）：药物基因组数据和知识的综合资源
Li Gong,Ryan P Owen,Winston Gor et al.
Li Gong et al.
The PharmGKB is a publicly available online resource that aims to facilitate understanding how genetic variation contributes to variation in drug response. It is not only a repository of pharmacogenomics primary data, but it also provides f...
Lincoln Stein
Lincoln Stein
The essence of bioinformatics is dealing with large quantities of information. Whether it be sequencing data, microarray data files, mass spectrometric data (e.g., fingerprints), the catalog of strains arising from an insertional mutagenesi...
The Gene Ontology (GO) project: structured vocabularies for molecular biology and their application to genome and expression analysis [0.03%]
基因本体论（GO）计划：分子生物学的结构词汇及其在基因组和表达分析中的应用
Judith A Blake,Midori A Harris
Judith A Blake
Scientists wishing to utilize genomic data have quickly come to realize the benefit of standardizing descriptions of experimental procedures and results for computer-driven information retrieval systems. The focus of the Gene Ontology proje...
Roderic D M Page
Roderic D M Page
TreeView provides a simple way to view the phylogenetic trees produced by a range of programs, such as PAUP*, PHYLIP, TREE-PUZZLE, and ClustalX. While some phylogenetic programs (such as the Macintosh version of PAUP*) have excellent tree p...
Mihaela Pertea,Steven L Salzberg
Mihaela Pertea
GlimmerM is a eukaryotic gene finder that has been used in the annotation of the genomes of Plasmodium falciparum (the malaria parasite), the model plant Arabidopsis thaliana, Oryza sativa (rice), the parasite Theileria parva, and the fungu...
Micheal Q Zhang
Micheal Q Zhang
MZEF (Michael Zhang's Exon Finder) was designed to help identify one of the most important classes of exons, i.e. the internal coding exons, in human genomic DNA sequences. It is neither for predicting intronless genes, nor for assembling p...
David Wheeler
David Wheeler
Every program for searching protein sequences against a database includes a choice of a protein weight matrix, also called a scoring matrix. Weight matrices add sensitivity to the search, while statistical significance adds selectivity. Vir...
Finding homologs to nucleotide sequences using network BLAST searches [0.03%]
利用网络BLAST搜索寻找核苷酸序列的同源物
Istvan Ladunga
Istvan Ladunga
Basic Local Alignment Search Tool (BLAST) can identify possible homologs in nucleotide and protein databases with high sensitivity and selectivity, and at an amazing speed. Those homologs may provide inference for the biochemical function, ...