David S Wishart,Anthony Wu
David S Wishart
DrugBank is a fully curated drug and drug target database that contains 8174 drug entries including 1944 FDA approved small-molecule drugs, 198 FDA-approved biotech (protein/peptide) drugs, 93 nutraceuticals, and over 6000 experimental drug...
Studying RNA Homology and Conservation with Infernal: From Single Sequences to RNA Families [0.03%]
用Infernal研究RNA同源性和保守性：从单个序列到RNA家族
Lars Barquist,Sarah W Burge,Paul P Gardner
Lars Barquist
Emerging high-throughput technologies have led to a deluge of putative non-coding RNA (ncRNA) sequences identified in a wide variety of organisms. Systematic characterization of these transcripts will be a tremendous challenge. Homology det...
The GeneCards Suite: From Gene Data Mining to Disease Genome Sequence Analyses [0.03%]
GeneCards基因集锦：从基因数据挖掘到疾病基因组序列分析
Gil Stelzer,Naomi Rosen,Inbar Plaschkes et al.
Gil Stelzer et al.
GeneCards, the human gene compendium, enables researchers to effectively navigate and inter-relate the wide universe of human genes, diseases, variants, proteins, cells, and biological pathways. Our recently launched Version 4 has a revampe...
William R Pearson
William R Pearson
The FASTA programs provide a comprehensive set of rapid similarity searching tools (fasta36, fastx36, tfastx36, fasty36, tfasty36), similar to those provided by the BLAST package, as well as programs for slower, optimal, local, and global s...
MetaboLights: An Open-Access Database Repository for Metabolomics Data [0.03%]
MetaboLights：代谢组学数据的开放数据库资源库
Namrata S Kale,Kenneth Haug,Pablo Conesa et al.
Namrata S Kale et al.
MetaboLights is the first general purpose, open-access database repository for cross-platform and cross-species metabolomics research at the European Bioinformatics Institute (EMBL-EBI). Based upon the open-source ISA framework, MetaboLight...
David S Wishart
David S Wishart
Cheminformatics is a field of information technology that focuses on the collection, storage, analysis, and manipulation of chemical data. The chemical data of interest typically includes information on small molecule formulas, structures, ...
Using PSEA-Quant for Protein Set Enrichment Analysis of Quantitative Mass Spectrometry-Based Proteomics [0.03%]
基于定量质谱的蛋白质组学中的蛋白质集富集分析的PSEA-Quant应用
Mathieu Lavallée-Adam,John R Yates rd
Mathieu Lavallée-Adam
PSEA-Quant analyzes quantitative mass spectrometry-based proteomics datasets to identify enrichments of annotations contained in repositories such as the Gene Ontology and Molecular Signature databases. It allows users to identify the annot...
UniProt Tools [0.03%]
UniProt工具套件
Sangya Pundir,Maria J Martin,Claire O&#x;Donovan;UniProt Consortium
Sangya Pundir
The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data (UniProt Consortium, 2015). The UniProt Web site receives ∼400,000 unique visitors per month and is the primary means to access U...
Jianyi Yang,Yang Zhang
Jianyi Yang
I-TASSER is a hierarchical protocol for automated protein structure prediction and structure-based function annotation. Starting from the amino acid sequence of target proteins, I-TASSER first generates full-length atomic structural models ...
Michael S Campbell,Mark Yandell
Michael S Campbell
Genome projects have evolved from large international undertakings to tractable endeavors for a single lab. Accurate genome annotation is critical for successful genomic, genetic, and molecular biology experiments. These annotations can be ...