The Role of Endoplasmic Reticulum Stress in Polycystic Ovary Syndrome and Exploration of Potential Therapeutic Targets [0.03%]
探讨多囊卵巢综合征中内质网应激的作用及潜在治疗靶点的研究
Yuanyuan Zhang,Yu Wang,Shan Wang et al.
Yuanyuan Zhang et al.
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in women. In recent years, endoplasmic reticulum (ER) stress has gained increasing attention in the pathogenesis of PCOS. This study aims to explore the potential role of ER st...
Effects of Carnitine and Coenzyme Q10 on Sperm Quality and Pregnancy Rates in Men with Unexplained Infertility: A Systematic Review and Network Meta-Analysis [0.03%]
肉碱和辅酶Q10对特发性不育男性精子质量和妊娠率影响的系统评价和网状Meta分析
Changmin Niu,Xueyu Lu,Yue Xie et al.
Changmin Niu et al.
Aims: To study and explore the effects of oral Carnitine and Coenzyme Q10 on the quality of sperm and the rate of pregnancy in males with unexplained infertility. ...
Investigation of the Efficacy of Umbilical Cord Mesenchymal Stem Cell and Melatonin Treatment in Premature Ovarian Failure Model [0.03%]
调查胎盘间充质干细胞与褪黑素治疗早发性卵巢衰竭模型的有效性研究
Aytaj Jafarzade,Elvan Anadol,Muzaffer Çaydere et al.
Aytaj Jafarzade et al.
Premature Ovarian Insufficiency (POI) may develop in young female patients due to chemotherapy treatments, which causes infertility. In addition to stem cell treatment, which is an effective method for POI in recent years, melatonin, which ...
ATF2-mediated Transcriptional Activation of USP4 Stabilizes KMT2A Protein and Promotes Trophoblast Dysfunction [0.03%]
ATF2介导的USP4转录激活稳定KMT2A蛋白并促进滋养细胞功能障碍
Jialin Liu,Ke Pan,Chunli Yang et al.
Jialin Liu et al.
Preeclampsia (PE) is a severe and prevalent complication of pregnancy, characterized by insufficient trophoblast invasion, placental hypoxia, and systemic inflammation, which collectively represent the central pathological mechanisms underl...
Association of Early-to-Mid-Luteal Serum Estradiol Levels with the Outcomes of Hormone Replacement Therapy-Frozen Embryo Transfer: A Systematic Review and Meta-Analysis [0.03%]
早期至中期黄体期血清雌二醇水平与冻胚移植后激素替代治疗结局相关性：系统综述和Meta分析
Azadeh Tarafdari,Fatemeh Keikha,Sepideh Ahmadi et al.
Azadeh Tarafdari et al.
This study aims to examine the relationship between early-to-mid-luteal estradiol levels and outcomes in hormone replacement therapy-frozen embryo transfers. A systematic search of PubMed, Scopus, Embase, and Web of Science databases was co...
MyD88 Signaling in Sertoli Cells Mediates LPS-Induced Orchitis in Mice [0.03%]
MYD88信号通路介导小鼠支持细胞脓毒性睾丸炎的发生与发展
Yuchuan Luo,Chang Yan,Jing Wang et al.
Yuchuan Luo et al.
Orchitis, a prevalent male reproductive disorder that can severely impair fertility and potentially result in infertility. Sertoli cells orchestrate testicular immune responses during orchitis by modulating local inflammation and maintainin...
Linking Ghrelin Elevation to Reproductive Dysfunction: Insights from Feed-Restricted Male Rats [0.03%]
胃饥饿素水平升高与生殖功能障碍的关系：饲料限制雄性大鼠中的研究启示
Marina M Ibrahim,E Seifelnasr,Marwa A Ibrahim et al.
Marina M Ibrahim et al.
Ghrelin, a peptide hormone consisting of 28 amino acids and primarily produced in the stomach, is crucial for stimulating appetite and maintaining energy balance. Beyond its role in hunger and metabolism, ghrelin also influences the hypotha...
Reproductive Performance and Obstetric Outcomes after Hysteroscopic Metroplasty for T Shaped Uterus [0.03%]
宫腔镜T形子宫矫形术后的生殖结局及围产期结局分析
Elif Aylin Taşkın,Kübra Dilbaz,Didem Demir et al.
Elif Aylin Taşkın et al.
The aim of this retrospective cohort study is to investigate the impact of hysteroscopic metroplasty for T-shaped uterus on reproductive and obstetric outcomes in patients admitted to our infertility clinic for unexplained infertility or hi...
CHAF1A Promotes Preadipocyte Differentiation and Contributes to Macrosomia in Gestational Diabetes Mellitus [0.03%]
CHAF1A促进孕糖尿病巨婴症的前脂肪细胞分化及作用机制研究
Dandan Xia,Xun Xu,Yuhui Zhang et al.
Dandan Xia et al.
Gestational diabetes mellitus (GDM) leads to macrosomia primarily due to fat accumulation caused by adipocyte differentiation. This study aims to investigate the role and underlying mechanisms of Chromatin assembly factor 1 subunit A (CHAF1...
Development and Validation of An Interpretable Machine Learning-Based Prediction Model of Postpartum Hemorrhage in Placenta Previa Following Cesarean Section: A Multicenter Study [0.03%]
一项关于胎盘前置的剖宫产术后产后出血的可解释机器学习预测模型的开发和验证的多中心研究
Mianmian Li,Xinhui Su,Wenxin Liao et al.
Mianmian Li et al.
The objective of this study is to predict the occurrence of postpartum hemorrhage in women with placenta previa based on machine learning. This retrospective study enrolled 845 singleton pregnant patients with placenta previa from two hospi...