Vitamin D Deficiency and VDR Gene Variants in Polycystic Ovary Syndrome: A Case-Control Study [0.03%]
维生素D缺乏和VDR基因多态性在多囊卵巢综合征中作用的病例对照研究
Sanchari Chakraborty,Randrita Pal,Farzana Begum et al.
Sanchari Chakraborty et al.
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder in reproductive-aged women and adolescents. Vitamin D deficiency (VDD) and genetic variations in the vitamin D receptor (VDR) pronouncedly influence its manifestations...
A High-Fat Diet Damages the Blood-Testis Barrier Through the PCSK9-LOX1 Positive Feedback Loop in Sertoli Cells [0.03%]
高脂饮食通过PCSK9-LOX1正反馈环损害支持细胞的血睾屏障
Gao Zhang,Zun Wang,Man He et al.
Gao Zhang et al.
We primarily investigated the correlation between long-term high-fat diet and male infertility, aiming to reveal the potential mechanisms underlying PCSK9-induced spermatogenic dysfunction in this context. Clinical data revealed that infert...
Combined Letrozole and Clomiphene Citrate Versus Letrozole Alone in Ovulation Induction for Polycystic Ovarian Syndrome Patients: A Systematic Review and Meta-analysis of Randomized Controlled Trials [0.03%]
来曲唑与氯米芬联用与单用来曲唑诱导多囊卵巢综合征排卵的对照试验的系统评价和 meta 分析
Zainah Abdulbari Alhebshi,Dalia Hamed Alqarni,Albaraa A Najjar et al.
Zainah Abdulbari Alhebshi et al.
Polycystic ovarian syndrome (PCOS) is a leading cause of infertility due to chronic anovulation. Letrozole is the first-line treatment for ovulation induction, but combination therapy with clomiphene citrate (CC) may enhance outcomes. We co...
Eric Han,Ramanaiah Mamillapalli,E Cansu Cevik et al.
Eric Han et al.
Endometriosis is a gynecological inflammatory disorder characterized by the presence of endometrial tissue outside of the uterus. It affects 10-15% of reproductive aged women, causing pelvic pain and infertility. Existing treatments for end...
Obesity-Associated Discordance Between Sperm PLCζ mRNA Expression and Protein Localization in Men: A Preliminary Evaluation [0.03%]
肥胖相关男性精子PLCζ mRNA表达与蛋白定位不一致的初步评估
Serpil Sude Yerlikaya,Nazlı Çil,Seyedmahdi Tabatabaei et al.
Serpil Sude Yerlikaya et al.
Obesity is associated with low fertility potential. Ca2 + oscillations are known to be triggered after sperm oocyte membrane fusion, which allows entry of a sperm-specific phospholipase C-zeta (PLCζ), into the oocyte cytoplasm. We aimed to...
Protective Effect of Soybean Isoflavone (SI) on Testicular Damages Induced by Zinc Oxide Nanoparticles (ZnONPs) in Male Mice [0.03%]
大豆异黄酮对锌 oxide纳米颗粒致小鼠睾丸损伤的保护作用研究
Haiwei He,Kaixuan Wang,Yadan Jin et al.
Haiwei He et al.
In recent years, with the increasing use of ZnONPs as a feed additive in animal diets, their potential impact on the animal reproductive system has garnered growing attention. The present study aimed to investigate the ameliorative effects ...
Challenges in Fertility Preservation for p53abn Grade 2 Endometrioid Endometrial Cancer: A Case Report and Literature Review [0.03%]
p53异常的二级子宫内膜样癌患者生育力保存面临的挑战：一例报告及文献复习
Ibrahim Yalcin,Hakan Kula,Alper Baysal et al.
Ibrahim Yalcin et al.
Endometrial carcinoma, the second most common gynecological cancer, is increasingly affecting younger women, particularly due to rising obesity rates. The need for precise molecular tools is paramount for better categorization and risk stra...
Blastocyst-Secreted miR-519d-3p Modulated the Cell Viability, Apoptosis and Migration of Human Endometrial Stromal Cells by Targeting HIF1α [0.03%]
囊胚来源的miR-519d-3p通过靶向HIF1α调节子宫内膜间质细胞增殖、凋亡及迁移的功能研究
Xiaodan Wang,Wenjuan Cai,Shuhong Pan et al.
Xiaodan Wang et al.
Bidirectional embryo-endometrial communication is critical for embryo implantation. As a bio-sensor of embryos, the human endometrium is capable of mounting a response tailored to individual embryos, but how embryos signal their development...
HERC2 as a Potential Biomarker for Prognosis and Response to Bevacizumab in Ovarian Cancer: A Bioinformatics Approach [0.03%]
HERC2作为预测卵巢癌预后和贝伐单抗治疗反应的生物标志物的生物信息学方法研究
Fatih Yay,Hasan Çağrı Yıldırım
Fatih Yay
It is thought that decreased HERC2 expression increases the sensitivity to ferroptosis in ovarian cancer cells and may increase the VEGF pathway in porcine endothelium by inhibiting LKB1. Based on these data, we aimed to determine whether H...
Sabri Saeed Sanabani
Sabri Saeed Sanabani
Endometriosis is a chronic gynecological disease characterized by the presence of endometrial-like tissue outside the uterus, leading to pain and infertility. Recent research has highlighted the important role of the microbiome in various h...