Expression of the cellular prion protein by mast cells in white-tailed deer carotid body, cervical lymph nodes and ganglia [0.03%]
白尾鹿颈动脉体、颈部淋巴结和神经节中肥大细胞表达细胞型朊蛋白
Anthony E Kincaid,Nathaniel D Denkers,Erin E McNulty et al.
Anthony E Kincaid et al.
Chronic wasting disease (CWD) is a transmissible and fatal prion disease that affects cervids. While both oral and nasal routes of exposure to prions cause disease, the spatial and temporal details of how prions enter the central nervous sy...
Correction [0.03%]
改正错误
Published Erratum
Prion. 2024 Dec;18(1):1-2. DOI:10.1080/19336896.2024.2359752 2024
Peter Hermann,Inga Zerr
Peter Hermann
Although the development of aggregation assays has noticeably improved the accuracy of the clinical diagnosis of prion diseases, research on biomarkers remains vital. The major challenges to overcome are non-invasive sampling and the explor...
Pavol Skacik,Egon Kurca,Stefan Sivak
Pavol Skacik
Authors are commenting on the evolving geographical incidence trends observed with the genetic form of Creutzfeldt-Jakob disease and discussing the diverse array of factors contributing to the heightened incidence rates observed in specific...
Prion forensics: a multidisciplinary approach to investigate CWD at an illegal deer carcass disposal site [0.03%]
鹿尸体非法处置现场慢性消耗性疾病的多学科调查方法研究
Marc D Schwabenlander,Jason C Bartz,Michelle Carstensen et al.
Marc D Schwabenlander et al.
Infectious prions are resistant to degradation and remain infectious in the environment for several years. Chronic wasting disease (CWD) has been detected in cervids inhabiting North America, the Nordic countries, and South Korea. CWD-prion...
Tiago F Outeiro,Tuane C R G Vieira
Tiago F Outeiro
The history of human prion diseases began with the original description, by Hans Gerhard Creutzfeldt and by Alfons Maria Jakob, of patients with a severe brain disease that included speech abnormalities, confusion, and myoclonus, in a disea...
A review of chronic wasting disease (CWD) spread, surveillance, and control in the United States captive cervid industry [0.03%]
美国圈养鹿群中慢性消耗病的传播、监测和控制的综述
Jameson Mori,Nelda Rivera,Jan Novakofski et al.
Jameson Mori et al.
Chronic wasting disease (CWD) is a fatal prion disease of the family Cervidae that circulates in both wild and captive cervid populations. This disease threatens the health and economic viability of the captive cervid industry, which raises...
Novel method for classification of prion diseases by detecting PrPres signal patterns from formalin-fixed paraffin-embedded samples [0.03%]
一种通过检测甲醛固定石蜡包埋样本中的PrPres信号模式来分类新型朊病毒病的方法
Sachiko Koyama,Kaoru Yagita,Hideomi Hamasaki et al.
Sachiko Koyama et al.
Prion disease is an infectious and fatal neurodegenerative disease. Western blotting (WB)-based identification of proteinase K (PK)-resistant prion protein (PrPres) is considered a definitive diagnosis of prion diseases. In this study, we a...
Mutations in human prion-like domains: pathogenic but not always amyloidogenic [0.03%]
人类朊病毒样结构域的突变：致病但并非总是淀粉样蛋白生成型
Andrea Bartolomé-Nafría,Javier García-Pardo,Salvador Ventura
Andrea Bartolomé-Nafría
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are multifunctional proteins with integral roles in RNA metabolism and the regulation of alternative splicing. These proteins typically contain prion-like domains of low complexity (PrLDs or...
Urwah Rasheed,Sana Khan,Minahil Khalid et al.
Urwah Rasheed et al.
Creutzfeldt Jakob Disease (CJD) is a rapidly progressive, fatal neurodegenerative disorder, also known as a subacute spongiform encephalopathy. There are three major subtypes of CJD i.e. Sporadic CJD, which occurs for reasons unbeknown to s...