Enhanced contactless dielectrophoresis enrichment and isolation platform via cell-scale microstructures [0.03%]
基于细胞尺度微结构的非接触式介电泳富集及分离平台
Jaka Čemažar,Temple A Douglas,Eva M Schmelz et al.
Jaka Čemažar et al.
We designed a new microfluidic device that uses pillars on the same order as the diameter of a cell (20 μm) to isolate and enrich rare cell samples from background. These cell-scale microstructures improve viability, trapping efficiency, a...
Low-frequency dielectrophoretic response of a single particle in aqueous suspensions [0.03%]
水悬浮液中单颗粒的低频介电泳响应
Jingyu Wang,Ming-Tzo Wei,H Daniel Ou-Yang
Jingyu Wang
We use optical tweezers-based dielectrophoresis (DEP) force spectroscopy to investigate the roles of the electrical double layer in the AC dielectric response of an individual colloidal particle in an aqueous medium. Specifically, we measur...
A scalable label-free approach to separate human pluripotent cells from differentiated derivatives [0.03%]
一种可扩展的无标记分离人多能细胞与其分化后代的方法
N A Willoughby,H Bock,M A Hoeve et al.
N A Willoughby et al.
The broad capacity of pluripotent human embryonic stem cells (hESC) to grow and differentiate demands the development of rapid, scalable, and label-free methods to separate living cell populations for clinical and industrial applications. H...
Human induced pluripotent stem cells derived endothelial cells mimicking vascular inflammatory response under flow [0.03%]
流動環境下模擬血管炎症反應的誘導多能干细胞源内皮细胞
Li Wang,Meng Xiang,Yingying Liu et al.
Li Wang et al.
Endothelial cells (ECs) have great potential in vascular diseases research and regenerative medicine. Autologous human ECs are difficult to acquire in sufficient numbers in vitro, and human induced pluripotent stem cells (iPSCs) offer uniqu...
Uncertainty quantification in modeling of microfluidic T-sensor based diffusion immunoassay [0.03%]
基于微流体T传感器的扩散免疫测定建模中的不确定量化问题
Aman Kumar Jha,Supreet Singh Bahga
Aman Kumar Jha
Comparison of experimental data with modeling predictions is essential for making quantitative measurements of species properties, such as diffusion coefficients and species concentrations using a T-sensor. To make valid comparisons between...
Carla Berrospe-Rodriguez,Claas Willem Visser,Stefan Schlautmann et al.
Carla Berrospe-Rodriguez et al.
We designed and built a microfluidic device for the generation of liquid jets produced by thermocavitation. A continuous wave (CW) laser was focused inside a micro-chamber filled with a light-absorbing solution to create a rapidly expanding...
Centrifugal sedimentation immunoassays for multiplexed detection of enteric bacteria in ground water [0.03%]
用于地下水多路分型检测的离心沉淀免疫测定法
Julia Litvinov,Scott T Moen,Chung-Yan Koh et al.
Julia Litvinov et al.
Waterborne pathogens pose significant threat to the global population and early detection plays an important role both in making drinking water safe, as well as in diagnostics and treatment of water-borne diseases. We present an innovative ...
Capillarity ion concentration polarization for spontaneous biomolecular preconcentration mechanism [0.03%]
毛细管离子浓度极化自发富集生物分子机制
Yoonjee Oh,Hyomin Lee,Seok Young Son et al.
Yoonjee Oh et al.
Ionic hydrogel-based ion concentration polarization devices have been demonstrated as platforms to study nanoscale ion transport and to develop engineering applications, such as protein preconcentration and ionic diodes/transistors. Using a...
Biomimetic channel modeling local vascular dynamics of pro-inflammatory endothelial changes [0.03%]
模拟局部血管动力学的仿生通道模型及其促炎症内皮细胞变化
Antony Thomas,H Daniel Ou-Yang,Linda Lowe-Krentz et al.
Antony Thomas et al.
Endothelial cells form the inner lining of blood vessels and are exposed to various factors like hemodynamic conditions (shear stress, laminar, and turbulent flow), biochemical signals (cytokines), and communication with other cell types (s...
Enhancement of microfluidic particle separation using cross-flow filters with hydrodynamic focusing [0.03%]
具有流体动力聚焦的交直流滤器在微流控粒子分离中的应用增强
Yun-Yen Chiu,Chen-Kang Huang,Yen-Wen Lu
Yun-Yen Chiu
A microfluidic chip is proposed to separate microparticles using cross-flow filtration enhanced with hydrodynamic focusing. By exploiting a buffer flow from the side, the microparticles in the sample flow are pushed on one side of the micro...