The advection of microparticles, MCF-7 and MDA-MB-231 breast cancer cells in response to very low Reynolds numbers [0.03%]
低雷诺数下微粒和MCF-7及MDA-MB-231乳腺癌细胞的输运行为研究
Sinéad T Morley,Michael T Walsh,David T Newport
Sinéad T Morley
The lymphatic system is an extensive vascular network that serves as the primary route for the metastatic spread of breast cancer cells (BCCs). The dynamics by which BCCs travel in the lymphatics to distant sites, and eventually establish m...
Qingzhen Yang,Qin Lian,Feng Xu
Qingzhen Yang
Organ-on-a-chip has emerged as a powerful platform with widespread applications in biomedical engineering, such as pathology studies and drug screening. However, the fabrication of organ-on-a-chip is still a challenging task due to its comp...
Vaskar Gnyawali,Mohammadali Saremi,Michael C Kolios et al.
Vaskar Gnyawali et al.
We present a simple technique to generate stable hydrodynamically focused flows by driving the flow with hydrostatic pressure from liquid columns connected to the inlets of a microfluidic device. Importantly, we compare the focused flows ge...
Masahiro Oono,Keisuke Yamaguchi,Amirul Rasyid et al.
Masahiro Oono et al.
Various microfluidic features, such as traps, have been used to manipulate flows, cells, and other particles within microfluidic systems. However, these features often become undesirable in subsequent steps requiring different fluidic confi...
Particle concentrating and sorting under a rotating electric field by direct optical-liquid heating in a microfluidics chip [0.03%]
基于微流控芯片中直接光液加热的旋转电场粒子聚焦与分离研究
Yu-Liang Chen,Hong-Ren Jiang
Yu-Liang Chen
We demonstrate a functional rotating electrothermal technique for rapidly concentrating and sorting a large number of particles on a microchip by the combination of particle dielectrophoresis (DEP) and inward rotating electrothermal (RET) f...
Maximizing particle concentration in deterministic lateral displacement arrays [0.03%]
确定性侧向位移阵列中粒子浓度的最大化
Shilun L Feng,Alison M Skelley,Ayad G Anwer et al.
Shilun L Feng et al.
We present an improvement to deterministic lateral displacement arrays, which allows higher particle concentration enhancement. We correct and extend previous equations to a mirror-symmetric boundary. This approach allows particles to be co...
Flow lithography in ultraviolet-curable polydimethylsiloxane microfluidic chips [0.03%]
紫外光固化聚二甲基硅氧烷微流控芯片中的流动光刻技术
Junbeom Kim,Heseong An,Yoojin Seo et al.
Junbeom Kim et al.
Flow Lithography (FL) is the technique used for the synthesis of hydrogel microparticles with various complex shapes and distinct chemical compositions by combining microfluidics with photolithography. Although polydimethylsiloxane (PDMS) h...
X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization [0.03%]
用于高通量筛选和优化介观膜蛋白结晶的x射线透明微流控芯片
Jeremy M Schieferstein,Ashtamurthy S Pawate,Chang Sun et al.
Jeremy M Schieferstein et al.
Elucidating and clarifying the function of membrane proteins ultimately requires atomic resolution structures as determined most commonly by X-ray crystallography. Many high impact membrane protein structures have resulted from advanced tec...
A549 and MRC-5 cell aggregation in a microfluidic Lab-on-a-chip system [0.03%]
微流控芯片中A549和MRC-5细胞的聚集行为研究
A Zuchowska,E Jastrzebska,K Zukowski et al.
A Zuchowska et al.
In this paper, we present a culture of A549 and MRC-5 spheroids in a microfluidic system. The aim of our work was to develop a good lung cancer model for the evaluation of drug cytotoxicity. Our research was focused on determining the progr...
Rapid isolation of blood plasma using a cascaded inertial microfluidic device [0.03%]
一种用于快速分离血液血浆的级联惯性微流控装置
M Robinson,H Marks,T Hinsdale et al.
M Robinson et al.
Blood, saliva, mucus, sweat, sputum, and other biological fluids are often hindered in their ability to be used in point-of-care (POC) diagnostics because their assays require some form of off-site sample pre-preparation to effectively sepa...