Drug absorption related nephrotoxicity assessment on an intestine-kidney chip [0.03%]
用于肠道-肾脏芯片的药物吸收相关肾毒性评价
Zhongyu Li,Wentao Su,Yujuan Zhu et al.
Zhongyu Li et al.
Drug absorption in the intestine is tightly related to drug-induced nephrotoxicity, which is a relatively common side effect in clinical practice. It highlights a great need to develop predictive models with high accuracy in the early stage...
J R Haliburton,S C Kim,I C Clark et al.
J R Haliburton et al.
Droplet microfluidic techniques can perform large numbers of single molecule and cell reactions but often require controlled, periodic flow to merge, split, and sort droplets. Here, we describe a simple method to convert aperiodic flows int...
Acetylated bovine serum albumin differentially inhibits polymerase chain reaction in microdevices [0.03%]
乙酰化牛血清白蛋白可微调微流控器件中的聚合酶链式反应
Naveen Ramalingam,Majid Ebrahimi Warkiani,Thomas Hai-Qing Gong
Naveen Ramalingam
Bovine serum albumin (BSA) is widely used as an additive in polymerase chain reaction (PCR)-based microfluidic devices to passivate reactors and alleviate nucleic-acid amplification. BSA is available commercially in two types: either acetyl...
Automatic optimization of drug cocktails on an integrated microfluidic system [0.03%]
基于集成微流控系统药物鸡尾酒的自动优化
Wen-Yen Huang,Ching-An Liu,Rong-Syuan Fan et al.
Wen-Yen Huang et al.
Drug cocktails have been popular for a variety of therapies of complicated diseases. Nevertheless, it is a tediously challenging task to optimize formulations, especially using traditional methods. Hence, an automatic system capable of prec...
Characterization of microfluidic clamps for immobilizing and imaging of Drosophila melanogaster larva's central nervous system [0.03%]
表征微流体夹具以固定和成像果蝇幼虫的中枢神经系统
Reza Ghaemi,Pouya Rezai,Fatemeh Rafiei Nejad et al.
Reza Ghaemi et al.
Drosophila melanogaster is a well-established model organism to understand biological processes and study human diseases at the molecular-genetic level. The central nervous system (CNS) of Drosophila larvae is widely used as a model to stud...
Evaluation and comparison of two microfluidic size separation strategies for vesicle suspensions [0.03%]
用于液滴悬浮液的两种微流控尺寸分离策略的评估和比较
Kari J Storslett,Susan J Muller
Kari J Storslett
Two size-based separation strategies are evaluated for suspensions consisting of giant unilamellar vesicles with a broad, continuous distribution of diameters. Microfluidic devices were designed to separate an initial suspension into larger...
An intra-droplet particle switch for droplet microfluidics using bulk acoustic waves [0.03%]
一种使用声全反射波的微流控液滴内粒子开关技术
Anna Fornell,Mathias Ohlin,Fabio Garofalo et al.
Anna Fornell et al.
To transfer cell- and bead-assays into droplet-based platforms typically requires the use of complex microfluidic circuits, which calls for methods to switch the direction of the encapsulated particles. We present a microfluidic chip where ...
Erratum: Publisher's Note: "Maximizing particle concentration in deterministic lateral displacement arrays" [Biomicrofluidics 11, 024121 (2017)] [0.03%]
出版商通告：「确定性侧向位移阵列中粒子浓度的最大化」[生物微流体学11，024121（2017）]
Shilun Feng,Alison M Skelley,Ayad G Anwer et al.
Shilun Feng et al.
[This corrects the article DOI: 10.1063/1.4981014.].
Published Erratum
Biomicrofluidics. 2017 May 12;11(3):039901. DOI:10.1063/1.4983666 2017
Fang Yu,Shuangmu Zhuo,Yinghua Qu et al.
Fang Yu et al.
We have developed a microfluidic system suitable to be incorporated with a metabolic imaging method to monitor the drug response of cells cultured on a chip. The cells were perfusion-cultured to mimic the blood flow in vivo. Label-free opti...
Siddharth Deshpande,Anthony Birnie,Cees Dekker
Siddharth Deshpande
Due to their cell membrane-mimicking properties, liposomes have served as a versatile research tool in science, from membrane biophysics and drug delivery systems to bottom-up synthetic cells. We recently reported a novel microfluidic metho...