A low-cost, plug-and-play inertial microfluidic helical capillary device for high-throughput flow cytometry [0.03%]
低成本即插即用型惯性微流体螺旋毛细管装置在高通量流式细胞仪中的应用
Xiao Wang,Hua Gao,Nadja Dindic et al.
Xiao Wang et al.
Glass capillary tubes have been widely used in microfluidics for generating microdroplets and microfibers. Here, we report on the application of glass capillary to inertial focusing of microparticles and cells for high-throughput flow cytom...
Microfluidic engineering of neural stem cell niches for fate determination [0.03%]
微流体工程神经干细胞生态位以决定细胞命运
Yachen Wang,Jingyun Ma,Na Li et al.
Yachen Wang et al.
Neural stem cell (NSC) transplantation has great therapeutic potential for neurodegenerative diseases and central nervous system injuries. Successful NSC replacement therapy requires precise control over the cellular behaviors. However, the...
A microfluidic device for isolation and characterization of transendothelial migrating cancer cells [0.03%]
一种用于分离和表征迁移癌细胞的微流控装置
Xin Cui,Weijin Guo,Yubing Sun et al.
Xin Cui et al.
Transendothelial migration of cancer cells is a critical stage in cancer, including breast cancer, as the migrating cells are generally believed to be highly metastatic. However, it is still challenging for many existing platforms to achiev...
S Oyola-Reynoso,C Frankiewicz,B Chang et al.
S Oyola-Reynoso et al.
We report a simple, efficient, one-step, affordable method to produce open-channel paper-based microfluidic channels. One surface of a sheet of paper is selectively calendared, with concomitant hydrophobization, to create the microfluidic c...
Simultaneous measurement of erythrocyte deformability and blood viscoelasticity using micropillars and co-flowing streams under pulsatile blood flows [0.03%]
基于微柱阵列和同轴流动的脉冲血流下红细胞变形能力与血液黏弹性同步测量方法
Yang Jun Kang
Yang Jun Kang
The biophysical properties of blood provide useful information on the variation in hematological disorders or diseases. In this study, a simultaneous measurement method of RBC (Red Blood Cell) deformability and blood viscoelasticity is prop...
Electrophoretic stretching and imaging of single native chromatin fibers in nanoslits [0.03%]
纳米狭缝中单条天然染色体纤维的电泳拉伸与成像
Jia-Wei Yeh,Kylan Szeto
Jia-Wei Yeh
Stretching single chromosomal DNA fibers in nanofluidic devices has become a valuable tool for studying the genome and more recently the epigenome. Although nanofluidic technology has been extensively used in single molecular DNA analysis, ...
Rapid, chemical-free breaking of microfluidic emulsions with a hand-held antistatic gun [0.03%]
一种手持式防静电枪，可实现微流控乳状液的快速无化学试剂破乳
Mohsen Karbaschi,Payam Shahi,Adam R Abate
Mohsen Karbaschi
Droplet microfluidics can form and process millions of picoliter droplets with speed and ease, allowing the execution of huge numbers of biological reactions for high-throughput studies. However, at the conclusion of most experiments, the e...
An open-pattern droplet-in-oil planar array for single cell analysis based on sequential inkjet printing technology [0.03%]
基于连续喷墨打印技术的单细胞分析开放式阵列油滴等平面排列研究
Chenyu Wang,Wenwen Liu,Manqing Tan et al.
Chenyu Wang et al.
Cellular heterogeneity represents a fundamental principle of cell biology for which a readily available single-cell research tool is urgently required. Here, we present a novel method combining cell-sized well arrays with sequential inkjet ...
Detection of C-reactive protein on an integrated microfluidic system by utilizing field-effect transistors and aptamers [0.03%]
基于场效应晶体管和适配体的集成微流控系统检测C-反应蛋白
Wei-Chieh Kao,Yen-Wen Chen,Chia-Ho Chu et al.
Wei-Chieh Kao et al.
Cardiovascular diseases (CVDs) cause more than 17 × 106 deaths worldwide on a yearly basis. Early diagnosis of CVDs is therefore of great need. The C-reactive protein (CRP) is an important biomarker for analyzing the risks of CVDs. In this...
A new microfluidic device design for a defined positioning of neurons in vitro [0.03%]
一种新型微流控装置的设计可在体外对神经元进行准确定位
Katharina Walczuch,Peter Renze,Claudia Ingensiep et al.
Katharina Walczuch et al.
A new triangle-shaped microfluidic channel system for defined cell trapping is presented. Different variants of the same basic geometry were produced to reveal the best fitting parameter combinations regarding efficiency and sensitivity. Va...