A compact microfluidic chip with integrated impedance biosensor for protein preconcentration and detection [0.03%]
一种集成阻抗式生物传感器的微流体芯片用于蛋白质浓缩及检测
Tuan Vu Quoc,Meng-Syuan Wu,Tung Thanh Bui et al.
Tuan Vu Quoc et al.
In this study, a low-cost, compact biochip is designed and fabricated for protein detection. Nanofractures formed by self-assembled gold nanoparticles at junction gaps are applied for ion enrichment and depletion to create a trapping zone w...
Sitong Zhou,Yu-Shan Huang,Paul D Kingsley et al.
Sitong Zhou et al.
Primitive erythroblasts (precursors of red blood cells) enter vascular circulation during the embryonic period and mature while circulating. As a result, primitive erythroblasts constantly experience significant hemodynamic shear stress. Sh...
A perforated microhole-based microfluidic device for improving sprouting angiogenesis in vitro [0.03%]
一种新型微穿孔微流控装置可促进体外血管新生
Sijia Chen,Liguang Zhang,Yi Zhao et al.
Sijia Chen et al.
Microfluidic technology is an important research tool for investigating angiogenesis in vitro. Here, we fabricated a polydimethylsiloxane (PDMS) microfluidic device with five cross-shaped chambers using a coverslip molding method. Then, the...
Tumor cell capture patterns around aptamer-immobilized microposts in microfluidic devices [0.03%]
微流控装置中aptamer固定的微柱周围肿瘤细胞的捕获模式
Kangfu Chen,Teodor Z Georgiev,Weian Sheng et al.
Kangfu Chen et al.
Circulating tumor cells (CTCs) have shown potential for cancer diagnosis and prognosis. Affinity-based CTC isolation methods have been proved to be efficient for CTC detection in clinical blood samples. One of the popular choices for affini...
A 3D-printed microbial cell culture platform with in situ PEGDA hydrogel barriers for differential substrate delivery [0.03%]
一种用于不同底物递送的具有原位PEGDA水凝胶屏障的三维打印微生物细胞培养平台
Andrea L Kadilak,Jessica C Rehaag,Cameron A Harrington et al.
Andrea L Kadilak et al.
Additive manufacturing, or 3D-printing techniques have recently begun to enable simpler, faster, and cheaper production of millifluidic devices at resolutions approaching 100-200 μm. At this resolution, cell culture devices can be construc...
Microfluidic cell concentrator with a reduced-deviation-flow herringbone structure [0.03%]
一种具有偏离度减小的鱼骨结构的微流体式细胞浓缩器
Ji-Chul Hyun,Jongchan Choi,Yu-Gyung Jung et al.
Ji-Chul Hyun et al.
In this study, a microfluidic cell concentrator with a reduced-deviation-flow herringbone structure is proposed. The reduced-deviation-flow herringbone structure reduces the magnitude of deviation flow by a factor of 3.3 compared to the ori...
On-chip cell labelling and washing by capture and release using microfluidic trap arrays [0.03%]
基于微流体陷阱阵列捕获与释放的芯片式细胞标记及清洗技术
Yu Chen,Robert H Austin,James C Sturm
Yu Chen
Flow cytometry analysis requires a large amount of isolated, labelled, and purified cells for accurate results. To address the demand for a large quantity of cells prepared in a timely manner, we describe a novel microfluidic trap structure...
Separation of sperm cells from samples containing high concentrations of white blood cells using a spiral channel [0.03%]
基于螺旋通道的高浓度样本中精子与白细胞分离
Jiyoung Son,Raheel Samuel,Bruce K Gale et al.
Jiyoung Son et al.
Microfluidic technology has potential to separate sperm cells from unwanted debris while improving the effectiveness of assisted reproductive technologies (ART). Current clinical protocol limitations regarding the separation of sperm cells ...
In vitro particulate analogue fluids for experimental studies of rheological and hemorheological behavior of glucose-rich RBC suspensions [0.03%]
用于研究高血糖红细胞悬液流变和血液流变行为的体外颗粒类似流体实验
Diana Pinho,Laura Campo-Deaño,Rui Lima et al.
Diana Pinho et al.
Suspensions of healthy and pathological red blood cells (RBC) flowing in microfluidic devices are frequently used to perform in vitro blood experiments for a better understanding of human microcirculation hemodynamic phenomena. This work re...
Multimodal microfluidic platform for controlled culture and analysis of unicellular organisms [0.03%]
一种用于单细胞生物培养和分析的多模态微流控平台
Tao Geng,Chuck R Smallwood,Erin L Bredeweg et al.
Tao Geng et al.
Modern live-cell imaging approaches permit real-time visualization of biological processes, yet limitations exist for unicellular organism isolation, culturing, and long-term imaging that preclude fully understanding how cells sense and res...