A microfluidic sucrose gap platform using trilaminar flow with on-chip switching and novel calibration: Challenges and limitations [0.03%]
具有片上切换和新型校准的三层流微流控蔗糖隙平台：挑战与局限性
J Dungan,J Mathews,M Levin et al.
J Dungan et al.
Gap junction connectivity is crucial to intercellular communication and plays a key role in many critical processes in developmental biology. However, direct analysis of gap junction connectivity in populations of developing cells has prove...
Processing and inspection of high-pressure microfluidics systems: A review [0.03%]
高压微流控系统加工与检测研究进展综述
Jiangyi Song,Shaoxin Meng,Jianben Liu et al.
Jiangyi Song et al.
In the field of microfluidics, high-pressure microfluidics technology, which utilizes high driving pressure for microfluidic analysis, is an evolving technology. This technology combines microfluidics and pressurization, where the flow of f...
Design of 3D printed chip to improve sensitivity of platelet adhesion through reinjection: Effect of alcohol consumption on platelet adhesion [0.03%]
一种改进血小板贴壁敏感性的3D打印芯片的再注流道设计：乙醇摄入对血小板贴壁的影响研究
Haebeen Kim,Hae-Ryoun Park,Jae Min Song et al.
Haebeen Kim et al.
Monitoring platelet aggregation is crucial for predicting thrombotic diseases and identifying the risk of bleeding or resistance to antiplatelet drugs. This study developed a microfluidic device to measure platelet activation with high sens...
Impact of dcEF on microRNA profiles in glioblastoma and exosomes using a novel microfluidic bioreactor [0.03%]
直流电场对胶质母细胞瘤及外泌体微小核糖核酸谱型影响的新型芯片研究
Hsieh-Fu Tsai,Amy Q Shen
Hsieh-Fu Tsai
Glioblastoma multiforme, the most common type of highly aggressive primary brain tumor, is influenced by complex molecular signaling pathways, where microRNAs (miRNAs) play a critical regulatory role. Originating from glial cells, glioblast...
Yuhan Li,Chuangyi Xu,Yifan Liao et al.
Yuhan Li et al.
Bio-microfluidic technologies offer promising applications in diagnostics and therapy, yet they face significant technical challenges, particularly in the need for external power sources, which limits their practicality and user-friendlines...
Titrating chimeric antigen receptors on CAR T cells enabled by a microfluidic-based dosage-controlled intracellular mRNA delivery platform [0.03%]
基于微流控的剂量控制型胞内mRNA递送平台实现CAR-T细胞接合臂滴度化
Yu-Hsi Chen,Mahnoor Mirza,Ruoyu Jiang et al.
Yu-Hsi Chen et al.
Chimeric antigen receptor (CAR) T-cell therapy shows unprecedented efficacy for cancer treatment, particularly in treating patients with various blood cancers, most notably B-cell acute lymphoblastic leukemia. In recent years, CAR T-cell th...
Recent developments in microfluidic passive separation to enable purification of platelets for transfusion [0.03%]
近年微流体无泵浦分离技术的发展使可用于输血的血小板得以提纯
Mai T P Dinh,Mubasher Iqbal,Kumar Abhishek et al.
Mai T P Dinh et al.
Platelet transfusion is a lifesaving therapy intended to prevent and treat bleeding. However, in addition to platelets, a typical unit also contains a large volume of supernatant that accumulates multiple pro-inflammatory contaminants, incl...
Miniaturized electrophoresis: An integrated microfluidic cartridge with functionalized hydrogel-assisted LAMP for sample-to-answer analysis of nucleic acid [0.03%]
微型电泳技术：集成微流控卡匣结合功能化水凝胶辅助LAMP用于核酸样本到答案分析
Natish Kumar,Monika Kumari,Devtulya Chander et al.
Natish Kumar et al.
Accurate detection of pathogenic nucleic acids is crucial for early diagnosis, effective treatment, and containment of infectious diseases. It facilitates the timely identification of pathogens, aids in monitoring disease outbreaks, and hel...
Mechanically mediated cargo delivery to cells using microfluidic devices [0.03%]
利用微流控装置对细胞进行机械介导的货物运输
Zhiyu Mao,Bori Shi,Jinbo Wu et al.
Zhiyu Mao et al.
Drug delivery technologies, which are a crucial area of research in the field of cell biology, aim to actively or passively deliver drugs to target cells to enhance therapeutic efficacy and minimize off-target effects. In recent years, with...
Thermal bubble single-cell printing chip: High-throughput, wide-field, and efficient [0.03%]
热气泡单细胞打印芯片：高通量、宽场和高效性
Bo Deng,Kun Wang,Peng Huang et al.
Bo Deng et al.
Single-cell printing technology has arisen as a potent instrument for investigating cell biology and disease pathophysiology. Nonetheless, current single-cell printing methodologies are hindered by restricted throughput, a limited field of ...