I Joanna Makowska,Daniel M Weary
I Joanna Makowska
Most would agree that animals in research should be spared "unnecessary" harm, pain, or distress, and there is also growing interest in providing animals with some form of environmental enrichment. But is this the standard of care that we s...
Reproducibility and Comparative aspects of Terrestrial Housing Systems and Husbandry Procedures in Animal Research Facilities on Study Data [0.03%]
动物实验设施中陆生饲养系统的再现性及饲养操作对实验数据的影响的比较方面研究标题：动物实验设施中陆地养殖系统和管理程序的可重复性和对实验数据影响的比较方面研究
John J Hasenau
John J Hasenau
As mentioned in other chapters, reproducibility of research data is very complicated and has numerous contributors for concerns. This chapter will discuss the animal housing systems and corresponding husbandry practices in regard to current...
From Unpleasant to Unbearable-Why and How to Implement an Upper Limit to Pain and Other Forms of Suffering in Research with Animals [0.03%]
从不愉快到不可忍受——为何及如何在动物实验中对痛苦及其他形式的折磨实施上限要求
I Anna S Olsson,Christine J Nicol,Steven M Niemi et al.
I Anna S Olsson et al.
The focus of this paper is the requirement that the use of live animals in experiments and in vivo assays should never be allowed if those uses involve severe suffering. This requirement was first implemented in Danish legislation, was late...
Patricia V Turner,R Wayne Barbee
Patricia V Turner
This issue of the ILAR Journal focuses on the topic of responsible science as it relates to animal research. We start with the concept of the scientist as a responsible citizen and then move through multiple phases of research including car...
Lane Warmbrod,Marc Trotochaud,Nancy Connell
Lane Warmbrod
The scientific enterprise satisfies the innate human urge to understand the world; these efforts have led to both improvements and dangers to society. The storied history of relationships between scientists and citizens suggests that the li...
Angela N Hvitved
Angela N Hvitved
The significance of ethical considerations for animal research policy has long been acknowledged, but the role of philosophical ethics in the policymaking process has been less clear. By comparing the ethical framework of animal research po...
Incorporating Laboratory Animal Science into Responsible Biomedical Research [0.03%]
将实验动物科学纳入负责任的生物医学研究中
R Wayne Barbee,Patricia V Turner
R Wayne Barbee
Biomedical research has made great strides in the past century leading to rapid advances in human life expectancy, all derived from improved understanding, prevention, and treatment of many diseases and conditions. Research involving labora...
S Mohan,R Huneke
S Mohan
Malcolm Macleod,Swapna Mohan
Malcolm Macleod
Increasing focus on issues of research reproducibility affords us the opportunity to review some of the key issues related in vivo research. First, we set out some key definitions, to guide the reader through the rest of the paper. Next we ...
The Pursuit and Advancement of Knowledge as a Justification for the Use of Animals in Research [0.03%]
获取和增进知识系利用动物从事实验的正当理由吗？
Jerrold Tannenbaum
Jerrold Tannenbaum
It is commonly said that animal research is sometimes ethically appropriate because it can lead to knowledge, irrespective of benefits this knowledge might bring to humans or animals. Proponents of this view, which I call the "knowledge jus...