Rebecca L Walker
Rebecca L Walker
This article appeals to virtue ethics to help guide laboratory animal research by considering the role of character and flourishing in these practices. Philosophical approaches to animal research ethics have typically focused on animal righ...
Craig L Franklin,Aaron C Ericsson
Craig L Franklin
Our bodies and those of our animal research subjects are colonized by bacterial communities that occupy virtually every organ system, including many previously considered sterile. These bacteria reside as complex communities that are collec...
The Influence of Feed and Drinking Water on Terrestrial Animal Research and Study Replicability [0.03%]
饲料和饮用水对陆生动物实验重复性的影响
David M Kurtz,William P Feeney
David M Kurtz
For more than 50 years, the research community has made strides to better determine the nutrient requirements for many common laboratory animal species. This work has resulted in high-quality animal feeds that can optimize growth, maintenan...
Holding Animal-Based Research to Our Highest Ethical Standards: Re-seeing Two Emergent Laboratory Practices and the Ethical Significance of Research Animal Dissent [0.03%]
以最高道德标准看待基于动物的研究——反思两种新兴实验室实践以及实验动物异议的伦理意义
Andrew Fenton
Andrew Fenton
"Animal-based research should be held to the highest ethical standards" is becoming an increasingly common refrain. Though I think such a commitment is what we should expect of those using animals in science, much as we would if the partici...
Sound and Vibration as Research Variables in Terrestrial Vertebrate Models [0.03%]
声波和振动在陆地脊椎动物模型中的研究变量
Randall Reynolds,Angela Garner,John Norton
Randall Reynolds
Sound and vibration have been shown to alter animal behavior and induce physiological changes as well as to cause effects at the cellular and molecular level. For these reasons, both environmental factors have a considerable potential to al...
Nonexperimental Xenobiotics: Unintended Consequences of Intentionally Administered Substances in Terrestrial Animal Models [0.03%]
无意中在陆地动物模型中使用有意给予的物质所产生的意外后果:非实验性外源物质的影响
Scott E Perkins,F Claire Hankenson
Scott E Perkins
Review of the use of nonexperimental xenobiotics in terrestrial animal models and the potential unintended consequences of these compounds, including drug-related side effects and adverse reactions. ...
Kathleen R Pritchett-Corning
Kathleen R Pritchett-Corning
Environmental complexity is an experimental paradigm as well as a potential part of animals' everyday housing experiences. In experimental uses, researchers add complexity to stimulate brain development, delay degenerative brain changes, el...
Erratum to: Reproducibility and Comparative aspects of Terrestrial Housing Systems and Husbandry Procedures in Animal Research Facilities on Study Data [0.03%]
关于:实验动物设施中陆地饲养系统和管理程序的可重复性及比较方面(对实验数据的影响)的勘误说明
John J Hasenau
John J Hasenau
Published Erratum
ILAR journal. 2020 Oct 19;60(2):298. DOI:10.1093/ilar/ilaa018 2020
The Influence of Behavioral, Social, and Environmental Factors on Reproducibility and Replicability in Aquatic Animal Models [0.03%]
行为、社会和环境因素对水生动物模型可重复性和可再现性的影响
Christine Lieggi,Allan V Kalueff,Christian Lawrence et al.
Christine Lieggi et al.
The publication of reproducible, replicable, and translatable data in studies utilizing animal models is a scientific, practical, and ethical necessity. This requires careful planning and execution of experiments and accurate reporting of r...
Katrien Devolder,Lauren J Yip,Thomas Douglas
Katrien Devolder
Rapid advances in gene-editing and stem-cell technology have expanded the range of possible future applications in human-animal chimera research. Most notably, recent developments may allow researchers to generate whole personalized human o...