Ke Ren,Ronald Dubner
Ke Ren
This article addresses important pain research models in nonhuman animals. These models attempt to mimic human persistent pain conditions. Models of persistent pain employ inflammatory agents that produce discomfort and hyperalgesia (i.e., ...
Charlotte P. Joyner,Lisa C. Myrick,Janet P. Crossland et al.
Charlotte P. Joyner et al.
Although laboratory mice (Mus) and rats (Rattus) are the most widely used research rodents, deer mice (Peromyscus maniculatus) and their congeneric species are favored as nontraditional alternatives for some purposes. Mice of the native gen...
Abigail L. Smith
Abigail L. Smith
The proliferation and increased use of genetically manipulated rodents are taxing laboratory animal facilities and diagnostic laboratories. Although serological testing remains the standard for monitoring immunologically intact animals, mol...
Floor Space Needs for Laboratory Mice: C56BL/6 Males in Solid-bottom Cages with Bedding [0.03%]
笼养小鼠的占地需求：带垫料的实底笼中C57BL/6雄性小鼠
Steven Fullwood,Tiffanie A. Hicks,Jack C. Brown et al.
Steven Fullwood et al.
Measures of performance, mortality, adrenal weights, plasma glucocorticoid concentration, and selected immune measures were collected in an attempt to define space needs of laboratory mice. Six replications of 3 C57BL/6 male mice per cage w...
Effects of Experience and Environment on the Developing and Mature Brain: Implications for Laboratory Animal Housing [0.03%]
环境与经历对发育中和成熟大脑的影响——兼论实验动物的饲养条件
Ann C Benefiel,William T. Greenough PhD
Ann C Benefiel
Decades of research have determined that an animal's brain structure and behavior are molded by experience. Expected experience that plays a critical role in early organization of the brain may be encoded via a process of overproduction of ...
Brigitte A. Cowell,Christine Wu,Suzanne M. J. Fleiszig
Brigitte A. Cowell
Despite medical advancements in available therapies, bacterial corneal infection frequently results in vision loss. Contact lens wear is a common predisposing factor for corneal infection; other reported risk factors are dry eye syndrome, b...
Animal Models of Myopia: Learning How Vision Controls the Size of the Eye [0.03%]
动物近视模型：学习视觉如何控制眼睛大小
Thomas T. Norton
Thomas T. Norton
As they grow up, approximately 25% of children in the United States become myopic (nearsighted). A much smaller fraction become significantly hyperopic (farsighted), while the majority develop little or no refractive error and are emmetropi...