Bioethical, Reproducibility, and Translational Challenges of Animal Models [0.03%]
动物模型的生物伦理、可重复性和转化性挑战
Margaret Landi,Jeffrey Everitt,B Berridge
Margaret Landi
There is no prescribed stage or standardized point at which an animal model protocol is reviewed for reproducibility and translatability. The method of review for a reproducible and translatable study is not consistently documented in peer ...
David J Schaeffer,CiRong Liu,Afonso C Silva et al.
David J Schaeffer et al.
The use of the common marmoset monkey (Callithrix jacchus) for neuroscientific research has grown markedly in the last decade. Magnetic resonance imaging (MRI) has played a significant role in establishing the extent of comparability of mar...
The Gastrointestinal Microbiota of the Common Marmoset (Callithrix jacchus) [0.03%]
常见狨猴（Callithrix jacchus）的肠道微生物群
Alexander Sheh
Alexander Sheh
The microbiota is heavily involved in both health and disease pathogenesis, but defining a normal, healthy microbiota in the common marmoset has been challenging. The aim of this review was to systematically review recent literature involvi...
The Marmoset: The Next Frontier in Understanding the Development of the Human Brain [0.03%]
Dwarf狐猴：理解人类大脑发育的新前沿
Jihane Homman-Ludiye,James A Bourne
Jihane Homman-Ludiye
Rodent models, particularly mice, have dominated the field of developmental neuroscience for decades, like they have in most fields of biomedicine research. However, with 80 million years since rodents and primates last shared a common ance...
Marmosets: Welfare, Ethical Use, and IACUC/Regulatory Considerations [0.03%]
关于巴西鼠兔福利、伦理使用及IACUC/监管考量的议题
Ricki J Colman,Saverio Capuano,Jaco Bakker et al.
Ricki J Colman et al.
Use of marmosets in biomedical research has increased dramatically in recent years due, in large part, to their suitability for transgenic applications and utility as models for neuroscience investigations. This increased use includes the e...
Anna Goodroe,Casey Fitz,Jaco Bakker
Anna Goodroe
Anesthetic and analgesics are essential components of both clinical and research procedures completed in marmosets. A review of current anesthetic and analgesic regimens for marmosets has been complied to provide a concise reference for vet...
Jon H Kaas
Jon H Kaas
Marmosets and closely related tamarins have become popular models for understanding aspects of human brain organization and function because they are small, reproduce and mature rapidly, and have few cortical fissures so that more cortex is...
The Importance of Complementary Collaboration of Researchers, Veterinarians, and Husbandry Staff in the Successful Training of Marmoset Behavioral Assays [0.03%]
金丝猴行为测定训练中研究人员、兽医和饲养员协同合作的重要性
Takeshi Murai,Stacey J Sukoff Rizzo
Takeshi Murai
Interest in marmosets as research models has seen exponential growth over the last decade, especially given that the research community is eager to improve on gaps with historical animal models for behavioral and cognitive disorders. The sp...
Steven J Schapiro,Sarah J Neal Webb,Michele M Mulholland et al.
Steven J Schapiro et al.
Behavioral management programs aim to enhance the welfare of animal subjects that participate in research, thereby enhancing our ability to conduct ethical research projects. Socialization strategies, environmental enrichment techniques, op...
Nathan Nobis
Nathan Nobis
Some animal research is arguably morally wrong, and some animal research is morally bad but could be improved. Who is most likely to be able to identify wrong or bad animal research and advocate for improvements? I argue that philosophical ...