A Structured Approach to Optimizing Animal Model Selection for Human Translation: The Animal Model Quality Assessment [0.03%]
优化动物模型选择以促进人类转化研究的结构化方法——“动物模型质量评估”项目
Joanne Storey,Thomas Gobbetti,Alan Olzinski et al.
Joanne Storey et al.
Animal studies in pharmaceutical drug discovery are common in preclinical research for compound evaluation before progression into human clinical trials. However, high rates of drug development attrition have prompted concerns regarding ani...
ICLAS LAQ Network for the Promotion of Animal Quality in Research [0.03%]
用于促进实验动物质量的国际实验动物科学协会LAQ网络
Patri Vergara,Gregory Ballard,Cynthia Besch-Williford et al.
Patri Vergara et al.
ICLAS Laboratory Animal Quality Network (LAQN) programs currently consist of the Performance Evaluation Program (PEP), which focuses on microbial monitoring by and for laboratory animal diagnostic laboratories, and the Genetic Reference Mon...
Erratum to: "But Mouse, You Are Not Alone": On Some Severe Acute Respiratory Syndrome Coronavirus 2 Variants Infecting Mice [0.03%]
“但鼠辈你并不孤单”——兼论感染小鼠的几种严重急性呼吸综合征冠状病毒2变异毒株的更名问题
Michael J Kuiper,Laurence O W Wilson,Shruthi Mangalaganesh et al.
Michael J Kuiper et al.
Published Erratum
ILAR journal. 2021 Dec 31;62(1-2):274. DOI:10.1093/ilar/ilac002 2021
"But Mouse, You Are Not Alone": On Some Severe Acute Respiratory Syndrome Coronavirus 2 Variants Infecting Mice [0.03%]
“但是鼠类，你并不孤单”——谈几种感染小鼠的严重急性呼吸系统综合征冠状病毒2变异毒株
Michael J Kuiper,Laurence O W Wilson,Shruthi Mangalaganesh et al.
Michael J Kuiper et al.
In silico predictions combined with in vitro, in vivo, and in situ observations collectively suggest that mouse adaptation of the severe acute respiratory syndrome 2 virus requires an aromatic substitution in position 501 or position 498 (b...
Research-Relevant Conditions and Pathology of Laboratory Mice, Rats, Gerbils, Guinea Pigs, Hamsters, Naked Mole Rats, and Rabbits [0.03%]
实验相关条件及用于研究的实验小鼠、大鼠、沙鼠、豚鼠、仓鼠、光头鼠和兔的病理学研究报告
Timothy K Cooper,David K Meyerholz,Amanda P Beck et al.
Timothy K Cooper et al.
Animals are valuable resources in biomedical research in investigations of biological processes, disease pathogenesis, therapeutic interventions, safety, toxicity, and carcinogenicity. Interpretation of data from animals requires knowledge ...
An Introduction to the Callithrix Genus and Overview of Recent Advances in Marmoset Research [0.03%]
呼叫虎属简介及近几十年树猴研究进展概述
Joanna Malukiewicz,Vanner Boere,Maria Adélia Borstelmann de Oliveira et al.
Joanna Malukiewicz et al.
We provide here a current overview of marmoset (Callithrix) evolution, hybridization, species biology, basic/biomedical research, and conservation initiatives. Composed of 2 subgroups, the aurita group (C aurita and C flaviceps) and the jac...
Research-Relevant Clinical Pathology Resources: Emphasis on Mice, Rats, Rabbits, Dogs, Minipigs, and Non-Human Primates [0.03%]
与研究相关的临床病理学资源：小鼠、大鼠、兔子、狗、微型猪和非人类灵长类动物的强调
Liza Bau-Gaudreault,Tara Arndt,Anne Provencher et al.
Liza Bau-Gaudreault et al.
Clinical pathology testing for investigative or biomedical research and for preclinical toxicity and safety assessment in laboratory animals is a distinct specialty requiring an understanding of species specific and other influential variab...
Livestock and Risk Group 4 Pathogens: Researching Zoonotic Threats to Public Health and Agriculture in Maximum Containment [0.03%]
家畜与四级风险病原体：在高度隔离条件下研究对公共健康和农业的动物源性威胁
Charles E Lewis,Bradley Pickering
Charles E Lewis
Maximum-containment laboratories are a unique and essential component of the bioeconomy of the United States. These facilities play a critical role in the national infrastructure, supporting research on a select set of especially dangerous ...
Elizabeth A Falendysz,Dana M Calhoun,Carrie A Smith et al.
Elizabeth A Falendysz et al.
Research with captive wildlife in Animal Biosafety Level 2 (ABSL2) and 3 (ABSL3) facilities is becoming increasingly necessary as emerging and re-emerging diseases involving wildlife have increasing impacts on human, animal, and environment...
Neuroethics and Animals: Report and Recommendations From the University of Pennsylvania Animal Research Neuroethics Workshop [0.03%]
神经伦理与动物：宾夕法尼亚大学关于动物实验的神经伦理研讨会报告及建议
Adam J Shriver,Tyler M John
Adam J Shriver
Growing awareness of the ethical implications of neuroscience in the early years of the 21st century led to the emergence of the new academic field of "neuroethics," which studies the ethical implications of developments in the neuroscience...