Clinical Efficacy and Safety of the Herbal Prescription, HH333, in Preventing Recurrent Stroke in Patients With Ischemic Stroke Induced by Small-Vessel Disease: Protocol for Multicenter, Double-Blind, Randomized, Prospective, Pilot Clinical Trial [0.03%]
基于小血管病性缺血性卒中的HH333方预防卒中复发的临床疗效及安全性：多中心、双盲、随机对照前瞻性试点临床试验方案
Han-Gyul Lee,Seungwon Kwon,Woo-Sang Jung et al.
Han-Gyul Lee et al.
Background: Patients with ischemic stroke are at high risk of recurrence, making preventive care an important factor. Current antiplatelet therapy for recurrence prevention treatment has several limitations. Recent retros...
Integration of Digital Phenotyping and Genomics for Dry Eye Disease: Protocol for a Prospective Cohort Study [0.03%]
数字表型和基因组学在干眼病整合研究中的应用：前瞻性队列研究方案
Ken Nagino,Yasutsugu Akasaki,Nobuo Fuse et al.
Ken Nagino et al.
Background: Dry eye disease (DED) is a common ocular condition with diverse and heterogeneous symptoms. Current treatment standards of DED include the post facto management of associated symptoms through topical eye drops...
The Prevalence of Hypertension Among Children and Antihypertensive Use: Protocol for a Systematic Review and Meta-Analysis [0.03%]
儿童高血压患病率及降压药使用情况系统评价和 meta 分析方案
Nur Hasnah Maamor,Nur Ain Zahidah Zainudin,Nur Liana Md Nasir et al.
Nur Hasnah Maamor et al.
Background: Early-onset hypertension (HT) presents compounded risks for cardiovascular, renal, and other systemic complications. Childhood HT is associated with HT during adulthood and detrimental lifelong cardiovascular ...
Addressing the Stigma of Mental Illness in Black Families and Communities in Ontario, Canada: Protocol for a Mixed Methods Study [0.03%]
加拿大安大略省黑人家庭和社区的精神疾病污名化问题应对方案：混合方法研究方案协议
Joseph Adu,Josephine P H Wong,Priscilla Boakye et al.
Joseph Adu et al.
Background: Racism and discrimination are among the factors perpetuating the persistent disparities within the Canadian health sector and related social and community services. Addressing issues of racism in Canada is cru...
Effect of Early Treatment of Spasticity After Stroke on Motor Recovery: Protocol for the Baclotox Multicenter, Double-Blind, Double-Dummy Randomized Controlled Trial [0.03%]
早期治疗卒中后痉挛对运动功能恢复的影响：巴氯芬治疗临床研究方案
Emmeline Montane,Nabila Brihmat,Camille Cormier et al.
Emmeline Montane et al.
Background: Individuals with poststroke hemiplegia often develop spasticity, which increases disability. Antispastic treatments such as baclofen and botulinum toxin are commonly prescribed in poststroke recovery. However,...
Telesimulation in Medical Education for High-Acuity Low-Occurrence Procedures and Clinical Encounters for Physicians and Medical Trainees in Emergency Medicine: Protocol for a Systematic Review [0.03%]
急诊医学中针对医师和医学生的高发病率低发生率程序及临床会诊的远程模拟医学教育：系统综述方案
Kurtis W Thornhill,Jennifer Jewer,Queen Jacques et al.
Kurtis W Thornhill et al.
Background: Proficiency in high-acuity low-occurrence (HALO) procedures and clinical encounters is crucial for physicians and medical trainees in emergency medicine. Simulation-based medical education (SBME) provides valu...
Telenursing Health Education and Lifestyle Modification Among Patients With Diabetes in Bangladesh: Protocol for a Pilot Study With a Quasi-experimental Pre- and Postintervention Design [0.03%]
孟加拉国糖尿病患者的远程护理健康教育和生活方式干预：准实验前后对照设计的试点研究方案
Michiko Moriyama,K A T M Ehsanul Huq,Lucy Mondol et al.
Michiko Moriyama et al.
Background: The global burden of chronic diseases is increasing and becoming a public health issue throughout the world. The use of telenursing is increasing significantly during and after the COVID-19 pandemic to treat a...
Metabolic Flexibility to Predict Lifestyle Interventions Outcomes (MEPHISTO): Protocol for Predictive Validation Study and Randomized Controlled Trial [0.03%]
代谢灵活性预测生活干预结果（梅菲斯托）：预测试验和随机对照试验的协议
Monika Ludlova,Kateřina Koudelková,Jitka Pallova et al.
Monika Ludlova et al.
Background: Weight loss is a cornerstone of obesity treatment and diabetes mellitus type 2 (T2D) prevention, but its implementation in clinical practice is limited by its perceived burden and variability in response. Pers...
Nonadherence to Diabetes Complications Screening in a Multiethnic Asian Population: Protocol for a Mixed Methods Prospective Study [0.03%]
亚洲多民族人群糖尿病并发症筛查不依从性：混合方法前瞻性研究方案
Amudha Aravindhan,Eva Fenwick,Aurora Wing Dan Chan et al.
Amudha Aravindhan et al.
Background: Yearly screening for microvascular complications of diabetes mellitus (DM), namely diabetic retinopathy (DR), diabetic nephropathy (DN), and diabetic foot complications (DFC), is recommended to reduce their in...
Characterization and Evaluation of Department of Veterans Affairs Commission on Accreditation of Rehabilitation Facilities-Accredited Interdisciplinary Pain Rehabilitation Programs: Protocol for a Mixed Methods Program Evaluation [0.03%]
美国退伍军人事务委员会认证的综合疼痛康复项目的特征和评估：混合方法项目评价协议
Jolie N Haun,Christopher A Fowler,Dustin D French et al.
Jolie N Haun et al.
Background: Veterans are more likely to experience chronic pain than civilians, with significant negative impacts on long-term health outcomes. Evidence for the effectiveness of prescription opioids for chronic pain manag...