Gait Rehabilitation Using Hybrid Assistive Limb in Patients With Lower Limb Amputation: Protocol for a Single-Arm Clinical Trial [0.03%]
用于下肢截肢患者的步行康复外骨骼机器人单组临床试验方案
Makoto Asaeda,Naoya Orita,Masashi Shimada et al.
Makoto Asaeda et al.
Background: Lower limb amputation rates are increasing owing to aging and vascular diseases. However, no standardized rehabilitation protocol has been established for regaining walking ability. Conventional rehabilitation...
Real-World Efficacy and Safety of Zishenyizhi Pill in Cognitive Impairment Associated with Cerebral Small Vessel Disease: A Multicenter Prospective Observational Study [0.03%]
补肾益智颗粒治疗脑小血管病相关认知障碍的疗效和安全性观察研究
Xiongxing Sun,Yao Xie,Rui Fang et al.
Xiongxing Sun et al.
Background: Cerebral small vessel disease (CSVD) is a leading cause of vascular cognitive impairment, contributing to 36%-67% of vascular dementia cases. Current therapies, primarily cholinesterase inhibitors, offer limit...
Effects of Prevention Messages for Electronic Gambling Machines on Behaviors and Cognitions: Protocol for a Two-Arm Stratified Block: Randomized Controlled Study [0.03%]
针对电子赌博机预防信息对其行为和认知影响的试验：分层区组随机对照试验方案
Benjamin Galipeau,Christian Jacques,Serge Sévigny et al.
Benjamin Galipeau et al.
Background: Electronic gambling machines and online gambling are the reputedly most damaging gambling type from a public health perspective. Pop-up messages are often used as a responsible gambling (RG) measure to prevent...
Acute Adenosine Receptor Antagonism in Combination With Acute Intermittent Hypoxia to Promote Breathing Plasticity in Amyotrophic Lateral Sclerosis: Protocol for a Randomized, Double-Blinded, Placebo-Controlled Trial [0.03%]
针对肌萎缩侧索硬化呼吸可塑性的腺苷受体拮抗剂与间歇性缺氧联合促进作用的随机、双盲、安慰剂对照试验方案
Priscila Sales de Campos,May Smith-Hublou,Wendy L Olsen et al.
Priscila Sales de Campos et al.
Background: Respiratory impairment is a major concern in amyotrophic lateral sclerosis (ALS), shortening survival and lowering quality of life. One therapy with promise to delay respiratory decline in ALS is acute intermi...
Experiences of Pregnant Women With a Positive HIV Status in Sub-Saharan Africa: Protocol for a Scoping Review [0.03%]
东非国家HIV阳性孕妇的治疗经历：循证卫生保健系统评价和实践指南网的方案综述
Esther Lydie Mbobnda Kapche,Sara Bibi Mitha,Firoza Haffejee
Esther Lydie Mbobnda Kapche
Background: The World Health Organization reports that HIV and AIDS remain a significant public health concern in sub-Saharan Africa, which hosts over 60% of the global population of people living with HIV. Among these, t...
Emerging Interventions to Improve Health Outcomes for People Aging With HIV: Protocol for a Mixed Methods Implementation Science Evaluation [0.03%]
改善HIV阳性老年人健康结局的新兴干预措施：混合方法实施科学评价方案
Richard Dunville,Sarah Hodge,Shannon TenBroeck et al.
Richard Dunville et al.
Background: In 2022, 54% of people with HIV were aged 50 years and older; however, clinical care for HIV in the United States often falls short of comprehensively integrating care for aging-related conditions. In response...
Maximizing Engagement, Trust, and Clinical Benefit of AI-Generated Recovery Support Messages for Alcohol Use Disorder: Protocol for an Optimization Study [0.03%]
提高酒精使用障碍患者对AI生成的康复支持信息的参与度、信任度和临床收益的最大化：优化研究方案
Kendra Wyant,Sarah J Sant&#x;Ana,Claire E Punturieri et al.
Kendra Wyant et al.
Background: Successful recovery from alcohol use disorder requires long-term lapse risk monitoring. Self-monitoring is difficult, given the dynamic, complex interplay of the many risk factors over time. An automated recov...
Urban Chinese Community-Dwelling Older Adults' Expectations Regarding the Delivery of Integrated Care Through Case Managers: Protocol for a Mixed Methods Study [0.03%]
中国城市社区老年人对综合护理案例经理提供模式的期望：混合方法研究方案
Yuanyuan Zhao,Boon-How Chew,Feng Zhou et al.
Yuanyuan Zhao et al.
Background: The rising burden of chronic diseases among older adults in China underscores the urgent need for an integrated and efficient health care system. Existing services are often fragmented, lacking coordination an...
Healthy Body and Mind Program to Improve Health Outcomes and Reduce Dementia Risk in People With Osteoarthritis: Protocol for a Feasibility and Acceptability Pilot Randomized Controlled Trial [0.03%]
改善骨关节炎患者健康结局和降低痴呆风险身心健康方案的可行性与接受度试点随机对照试验方案
Claire V Burley,William Yeates,Kelly A McLeod et al.
Claire V Burley et al.
Background: Globally, approximately 55 million people are living with dementia. Osteoarthritis occurs in half of all older adults and is associated with pain, depression, and increased dementia risk. Currently, no program...
A Freely Accessible, Anonymous Online Treatment for Social Anxiety: Protocol for a Partially Randomized Patient Preference Trial [0.03%]
一种可供自由访问的、匿名的在线治疗社交焦虑的方案：部分随机患者偏好试验方案研究报告
Stefanie Arnold,Michael Felix Vogt,Johanna Boettcher et al.
Stefanie Arnold et al.
Background: Many people with mental health problems do not receive the care they need. Digital mental health interventions have been shown to be effective in many trials and offer a promising way to reach more people in n...