Using AI Algorithms and Machine Learning in the Analysis of a Bio-Purification Method (Therapeutic Emesis, Known as "Vamana Karma"): Protocol for a Mixed Methods Study [0.03%]
基于人工智能算法和机器学习的生物净化方法（催吐疗法，又称“梵摩那 karma”）分析：混合方法研究方案
Pooja Rani,Sumit Kalra,Sachin Singh et al.
Pooja Rani et al.
Background: Therapeutic emesis (TE), known as vamana karma, is a classical method of detoxification performed to eliminate vitiated kapha (bio-humor governing fluid regulation and structural cohesion of the body in normal...
Optimizing Antiemetic Support in Anthracycline-Based Chemotherapy for Early Breast Cancer: Protocol for a Prospective Observational Study of Four-Drug Antiemetic Therapy Including Fosnetupitant and Olanzapine [0.03%]
基于蒽环类化疗的早期乳腺癌患者止吐支持优化：四项止吐疗法（包括福沙匹坦和奥氮平）前瞻性观察研究方案
Ayako Higuchi,Yumiko Koi,Tomoaki Eto et al.
Ayako Higuchi et al.
Background: Prophylaxis for chemotherapy-induced nausea and vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC) is essential. Four-drug antiemetic therapy, consisting of a neurokinin-1 receptor anta...
Development and Feasibility Assessment of an Intrinsic Capacity Program in Primary Care: Protocol for an Implementation Science Approach [0.03%]
基层医疗内在能力项目的发展与可行性评估：实施科学方法的方案研究
Qing Wang,Mimaika Luluina Ginting,Ezra Ho et al.
Qing Wang et al.
Background: The World Health Organization (WHO) public health framework for healthy aging advocates for action on the trajectories of intrinsic capacity (IC) across a person's life course to optimize functional ability. W...
Developing a Multimodal Screening Algorithm for Mild Cognitive Impairment and Early Dementia in Home Health Care: Protocol for a Cross-Sectional Case-Control Study Using Speech Analysis, Large Language Models, and Electronic Health Records [0.03%]
针对居家护理中轻度认知障碍和早期痴呆的多模态筛查算法开发：使用语音分析、大型语言模型和电子健康记录进行横断面病例对照研究的方法学方案
Maryam Zolnoori
Maryam Zolnoori
Background: Mild cognitive impairment and early dementia (MCI-ED) are frequently unrecognized in routine care, particularly in home health care (HHC), where clinical decisions are made under time constraints and cognitive...
Addressing Gaps in the Hypertension and Diabetes Care Continuum in Rural Bangladesh Through Digital Technology Supported Decentralized Primary Care: Study Protocol and Baseline Results for a Hybrid Effectiveness-Implementation Trial [0.03%]
基于数字技术的分散式基层医疗在农村地区解决高血压和糖尿病诊疗缺口：混合有效性实施试验方案及基线结果
Wubin Xie,Sabrina Ahmed,Ali Ahsan et al.
Wubin Xie et al.
Background: Hypertension and diabetes are very common, interrelated chronic conditions. Awareness, diagnosis, treatment, and control rates of these conditions remain low, and access to quality care-particularly in rural a...
Establish a PrEP (Pre-Exposure Prophylaxis) Epidemiology, Modeling, and Surveillance (PREMISE) System to Analyze Trends in PrEP Uptake and the Impact of PrEP Programs and Policies: Protocol for a Natural Experiment and Modeling Study in the United States [0.03%]
建立PrEP（暴露前预防）流行病学、建模和监测(PREMISE)系统以分析PrEP采纳趋势及PrEP项目和政策的影响：在美国进行自然实验与建模研究的方案
Aaron J Siegler,Shi Hao Ernest Koh,Wenting Huang et al.
Aaron J Siegler et al.
Background: Pre-exposure prophylaxis (PrEP) is highly effective in preventing HIV transmission; yet, many people who would benefit from PrEP are not currently using it. Numerous programs and policies, including those prov...
Role of Shame and Concealment in Patient-Provider Communication Among Individuals With Low Health Literacy: Protocol for a Scoping Review [0.03%]
低健康素养个体中患者与提供者之间沟通中的耻辱和隐瞒作用：系统评价方案
Tsuyoshi Okuhara,Hiroko Okada,Rie Yokota
Tsuyoshi Okuhara
Background: Health literacy, defined as the ability to obtain, understand, evaluate, and use health information, influences health behaviors and outcomes. Low health literacy (LHL) is associated with misunderstandings of ...
Brief Intervention for Discontinuing Inappropriate Z-Hypnotic Use Among Older Patients in Primary Care: Protocol for a Cluster Randomized Controlled Trial With a Single Crossover [0.03%]
在初级保健中简短干预以帮助老年患者停止不恰当地使用Z类镇静催眠药物：群随机对照试验的协议及单次交叉实验
Tahreem Ghazal Siddiqui,Maria Torheim Bjelkarøy,Tone Breines Simonsen et al.
Tahreem Ghazal Siddiqui et al.
Background: Older patients are frequent users of Z-hypnotics despite consensus recommendations against extended use. Inappropriate Z-hypnotic use among older patients is frequently reported, posing risks of side effects a...
The Effect of Evening Technology Use on Objective Sleep in Older Adults: Protocol for a Crossover Randomized Controlled Trial [0.03%]
晚间使用技术设备对老年人客观睡眠影响的交叉随机对照试验方案
Sarah Nauman Ghazi,Anders Behrens,Joakim Niklasson et al.
Sarah Nauman Ghazi et al.
Background: Evening technology use (ETU) has been associated with sleep disturbances, often attributed to blue light exposure and cognitive arousal. However, most of the existing evidence focuses on younger populations an...
Efficacy of Acupuncture for Mild to Moderate Depression in Older People: Protocol for a Randomized Controlled Trial [0.03%]
针刺治疗老年人轻中度抑郁的疗效研究：随机对照试验方案
Qingnan Fu,Kaihui Xiao,Jie Zhang et al.
Qingnan Fu et al.
Background: Selective serotonin reuptake inhibitors are first-line antidepressants; however, only approximately 60% of patients can benefit from them. There is insufficient evidence for using acupuncture for symptom relie...