IL-6/GP130/JAK/STAT3 Pathway Activation in Pancreatic Ductal Adenocarcinoma and Its Association With Clinical Features: Protocol for a Retrospective Cross-Sectional Study [0.03%]
胰腺导管腺癌中 IL-6/GP130/JAK/STAT3 通路活化与临床特征相关性的横断面研究：协议文件
Claudia Mellenthin,Fabien Schaller,Lucie Vignot et al.
Claudia Mellenthin et al.
Background: The proinflammatory cytokine interleukin 6 (IL-6) contributes to pancreatic tumorigenesis by activating the Janus kinase (JAK)-signal transducer and activator of transcription 3 (STAT3) signaling cascade. Targ...
Evaluating AI-Generated Podcasts Versus Traditional Reading for Learning From Medical Articles: Protocol for a Mixed-Design Study Among Resident Physicians [0.03%]
评估AI生成的播客与传统阅读在医生 resident医师学习医学文章中的效果：混合设计研究方案
Matthias Stadler,Constanze Richters,Martin R Fischer et al.
Matthias Stadler et al.
Background: Podcasts have emerged as a popular medium in medical education over the past decade. Audio learning allows flexibility and may help residents engage with content in new ways. Reading scientific literature is a...
The 5 R's of Indigenous Research as a Framework to Co-Design and Evaluate an Outdoor Play Program in Early Learning and Child Care Centers: Protocol for the Promoting Early Childhood Outside (PRO-ECO) 2.0 Wait-List Control Cluster Randomized Trial [0.03%]
以土著研究的五个要素为框架共同设计和评估早期教育及儿童保育中心户外游戏项目：等待名单对照分群随机试验(PRO-ECO 2.0)方案描述
Mariana Brussoni,Rachel Ramsden,Sheila Grieve et al.
Mariana Brussoni et al.
Background: Outdoor play is a fundamental part of childhood. Children's participation in outdoor play connects them to nature and the land, and supports their role in the natural world. Early learning and child care (ELCC...
Co-Design of a Digital Health Platform for Chronic Disease Management in Rural Settings Using a Person-Centered, Collaborative-Care Model: Protocol for a 3-Phase Mixed Methods Study [0.03%]
基于以患者为中心的协作护理模式在农村地区进行慢性病管理的数字健康平台协同设计：混合方法三阶段研究方案
Amanda Ellen Young,Britt Klein,Priscilla R Prestes et al.
Amanda Ellen Young et al.
Background: Chronic diseases represent a significant global burden, accounting for 85% of the total disease burden in Australia. This burden is particularly pronounced in rural areas, where chronic disease rates are highe...
Improving Experimental Designs for Interventions to Reduce Intimate Partner Violence: Protocol for Refinements to Single-Case Experimental Design for a Safety Planning Intervention in Ontario, Canada [0.03%]
加拿大安大略省针对亲密伴侣暴力减少干预措施的实验设计改进：安全计划干预单例实验设计完善方案协议
Patricia O&#x;Campo,Nicholas Metheny,Pearl Buhariwala et al.
Patricia O&#x;Campo et al.
Background: Intimate partner violence (IPV) affects 2 in 5 women in Canada, leading to both physical and mental health consequences. Safety planning is a secondary prevention intervention designed to assist those experien...
Effects of Aromatherapy on Chemotherapy-Induced Gastrointestinal Toxicity in Patients With Cancer: Protocol for a Systematic Review and Meta-Analysis of Randomized Controlled Trials [0.03%]
芳香疗法对癌症患者化疗所致胃肠毒性作用的影响：随机对照试验的系统评价和meta分析方案研究
Hongrui Shi,Xin Chen,Xinxin Fan et al.
Hongrui Shi et al.
Background: Chemotherapy-induced gastrointestinal toxicity (CIGT) is a common and distressing adverse effect in cancer care, manifesting as nausea, vomiting, appetite loss, oral mucositis, constipation, and diarrhea. Thes...
Validation and Testing of a Suicide Prevention Program in Preventing Suicidal Ideation and Improving the Mental Well-Being of School-Going Adolescents: Protocol for a Pre-Post Intervention Study [0.03%]
一项预防计划的验证及测试：预先/事后介入研究方案——该计划旨在防止在校青少年产生自杀念头并改善其心理健康状况
Yasmin Nadeem Parpio,Rozina Nuruddin,Tazeen Saeed Ali et al.
Yasmin Nadeem Parpio et al.
Background: Globally, around 800,000 people die by suicide annually, with 77% of these deaths occurring in low- and middle-income countries. Suicidal ideation, frequently observed among adolescents, is directly linked to ...
Correction: Developing a Core Outcome Set and a Core Outcome Measurement Set for Studies Evaluating Interventions to Minimize Physical Restraint Use in Adult Intensive Care Units: Protocol for a Modified Delphi Study [0.03%]
对ICU成人患者减使用物理约束干预措施的研究建立核心结果变量集和核心测量指标集的修正方案：一项改良德尔菲研究的协议
Ziad Alostaz,Wendy L Ellis,Sangeeta Mehta et al.
Ziad Alostaz et al.
[This corrects the article DOI: 10.2196/76405.]. ©Ziad Alostaz, Wendy L Ellis, Sangeeta Mehta, Mohammed Aldalaykeh, Nasrin Alostaz, Raajpreet Sekhon, Ab...
Published Erratum
JMIR research protocols. 2025 Dec 11:14:e88851. DOI:10.2196/88851 2025
Perinatal Cannabis Use, Depression, and the Mother-Child Dyad: Protocol for a Prospective Multimethod Study [0.03%]
产前使用大麻、抑郁与母婴二人组：前瞻性多方法研究方案
Lauren Micalizzi,Lindy K Howe,Cynthia L Battle et al.
Lauren Micalizzi et al.
Background: Postpartum depression (PPD) rates in the United States are among the highest globally, and PPD can pose significant, long-term risks to families. Concurrently, perinatal cannabis use is increasing in prevalenc...
Comparative Evaluation of the Effectiveness of Demineralized Freeze-Dried Bone Allografts With Titanium Platelet-Rich Fibrin and Autologous Dentin Graft With Titanium Platelet-Rich Fibrin for Alveolar Socket Preservation: Protocol for a Randomized Controlled Trial [0.03%]
关于钛富血小板纤维蛋白脱矿冻干骨异体移植与自体牙本质移植用于保存型牙槽窝的随机对照试验方案的效力比较评估
Shivani Thakre,Pavan Bajaj
Shivani Thakre
Background: Postextraction ridge resorption compromises the aesthetics and function of the subsequent implant therapy or prosthetic rehabilitation. Several techniques are employed to reduce ridge resorption, ranging from ...