Novel Utilization of Circulating Tumor DNA in Primary Dedifferentiated Seminal Vesicle Adenocarcinoma: A Case Report of Molecular Clearance Following Multimodal Therapy [0.03%]
原发性去分化精囊腺癌循环肿瘤DNA的新型应用：多模式治疗后分子学缓解的一例报告
Kamil Malshy,Brendan J Guercio,Laena Hines et al.
Kamil Malshy et al.
Primary seminal vesicle adenocarcinoma (PSVA) is an exceptionally rare malignancy, with fewer than 100 cases reported worldwide and poses significant diagnostic and surveillance challenges due to its deep pelvic location, nonspecific clinic...
Case Reports
Journal of medical cases. 2026 Jan 13;17(2):62-69. DOI:10.14740/jmc5238 2026
Intravenous Thiamine-Induced Thrombocytopenia in a Patient With Chronic Adrenal Insufficiency [0.03%]
慢性肾上腺功能不全患者静脉注射维生素B1导致血小板减少症病例报告
Mohammed Ayed Alanazi
Mohammed Ayed Alanazi
Thiamine (vitamin B1) is generally considered safe, with rare adverse effects, including anaphylaxis. Although thrombocytopenia related to thiamine deficiency is known to improve with supplementation, thrombocytopenia occurring after thiami...
Case Reports
Journal of medical cases. 2026 Jan 4;17(2):75-79. DOI:10.14740/jmc5250 2026
Long-Term Disease-Free Survival After Sorafenib-Combined Chemotherapy for Refractory Metastatic Testicular Germ Cell Tumor: A Five-Year Follow-Up [0.03%]
索拉非尼联合化疗治疗难治性继发性睾丸生殖细胞癌的长期无病生存：一项为期五年的随访研究
Hong Liang Gao,Yue Jia Du,Zi Yi Wu et al.
Hong Liang Gao et al.
The management of late-stage refractory metastatic non-seminomatous germ cell tumor (NSGCT) remains a significant challenge in oncology. While first-line BEP (bleomycin, etoposide, cisplatin) chemotherapy achieves high cure rates in most pa...
Case Reports
Journal of medical cases. 2026 Jan 4;17(2):54-61. DOI:10.14740/jmc5235 2026
Cyclophosphamide for the Treatment of Refractory Immune Effector Cell-Associated Neurotoxicity Syndrome Following CD19-Targeted CAR T-Cell Therapy [0.03%]
环磷酰胺治疗CD19靶向CAR-T细胞疗法后难治性免疫效应细胞相关神经毒性综合征的效果评估
Austin Frisch,Loren Marino,Deena Alsaadi et al.
Austin Frisch et al.
Immune effector cell-associated neurotoxicity syndrome (ICANS) is a serious complication of chimeric antigen receptor T-cell (CAR-T) therapy, associated with significant morbidity and mortality. While corticosteroids and anakinra are corner...
Case Reports
Journal of medical cases. 2025 Dec 24;17(1):28-31. DOI:10.14740/jmc5211 2025
Flumazenil Reversal of Remimazolam Sedation During Posterior Spinal Fusion in Two Adolescents [0.03%]
氟马西尼逆转右美托咪定镇静下青少年后路脊柱融合手术的案例报告
Nikole Lee,Kelly Moon,Joshua C Uffman et al.
Nikole Lee et al.
Remimazolam is a novel, ester-metabolized benzodiazepine, which received approval by the United States Food and Drug Administration (FDA) for procedural sedation in adults in 2020. Since then, its clinical uses have expanded to intraoperati...
Case Reports
Journal of medical cases. 2025 Dec 24;17(1):32-36. DOI:10.14740/jmc5221 2025
Refractory Epstein-Barr Virus-Negative Diffuse Large B-Cell Lymphoma Post-Transplant Lymphoproliferative Disorder in a Renal Transplant Patient Treated With Bispecific Antibody Therapy [0.03%]
一种肾移植患者接受双特异性抗体治疗的移植物抗淋巴增殖性疾病的难治性非EB病毒弥漫性大B细胞淋巴瘤病例
Austin Frisch,Bobby Se,Eric Martin et al.
Austin Frisch et al.
Post-transplant lymphoproliferative disorder (PTLD) is a rare disorder that can occur in both stem cell and organ transplant recipients. Most cases of PTLD arise from Epstein-Barr virus (EBV)-induced oncogenesis but it can be EBV-negative. ...
Case Reports
Journal of medical cases. 2025 Oct 10;17(1):1-8. DOI:10.14740/jmc5186 2025
Anesthetic and Transfusion Management in Placenta Accreta Spectrum: Lessons From a Resource-Limited Setting and Mini-Review [0.03%]
胎盘植入谱系疾病的麻醉和输血管理：来自医疗资源有限地区的一课及相关简要综述
Alma Soxhuku Isufi,Genci Hyska,Kastriot Dallaku et al.
Alma Soxhuku Isufi et al.
Placenta accreta spectrum (PAS) is a severe obstetric condition characterized by abnormal placental invasion of the myometrium, often resulting in massive hemorrhage and high maternal morbidity and mortality. Optimal management requires ear...
Case Reports
Journal of medical cases. 2025 Dec 24;17(1):21-27. DOI:10.14740/jmc5204 2025
Acute Myeloid Leukemia With a Non-Canonical FLT3 V491L Mutation: A Case Report With Ex Vivo FLT3 Inhibitors Sensitivity Testing [0.03%]
FLT3非经典V491L突变急性髓系白血病病例报告及体外FLT3抑制剂敏感性检测
Mateusz Pospiech,Michelle P Ngo,Misk Alrawashdeh et al.
Mateusz Pospiech et al.
Approximately 30% of patients with acute myeloid leukemia (AML) harbor FMS-like tyrosine kinase 3 (FLT3) mutations, which are associated with poor overall survival. Although United States Food and Drug Administration (FDA)-approved FLT3 inh...
Case Reports
Journal of medical cases. 2025 Dec 24;17(1):14-20. DOI:10.14740/jmc5197 2025
Delayed Presentation of Metachronous Ascending Colonic Adenocarcinoma in Early-Onset Colorectal Cancer Undergoing Curative Resection [0.03%]
早发性结直肠癌根治术后升结肠腺癌的延迟诊断报告
Budhi Ida Bagus,Febriagi Bayu Aji,Nafa Unnisa et al.
Budhi Ida Bagus et al.
Colorectal cancer (CRC) is the third most common cancer in both age groups in the world and one of the increasing causes of mortality each year. Particularly in early-onset colorectal cancer (EOCRC), this age group tends to metastasize to d...
Case Reports
Journal of medical cases. 2025 Dec 24;17(1):9-13. DOI:10.14740/jmc5184 2025
Acute Compartment Syndrome Following Non-Displaced Proximal Ulnar and Distal Radial Fractures in a Four-Year-Old Girl [0.03%]
四岁女孩桡骨远端和肱骨近端骨折后发生急性四肢室综合征病例报告
Khalid Aloqeely,Amal Yousif,Fatima Aljaziri
Khalid Aloqeely
Acute compartment syndrome (ACS) is a rare but limb-threatening emergency in children, usually associated with displaced fractures, crush injuries, or high-energy trauma. Prompt recognition and fasciotomy are essential to prevent permanent ...
Case Reports
Journal of medical cases. 2025 Dec 24;17(1):37-40. DOI:10.14740/jmc5223 2025