Histone Lactylation-Driven Ubiquitin-Specific Protease 34 Promotes Cisplatin Resistance in Hepatocellular Carcinoma [0.03%]
组蛋白乳酸化驱动的特异性泛素蛋白酶34促进肝细胞癌顺铂耐药性的研究
Ming Fan,Jian Shan Liu,Xi Le Wei et al.
Ming Fan et al.
Background: Ubiquitin-specific protease 34 (USP34) is a deubiquitinase that has been shown to play a critical role in the process of tumor drug-resistance. The objective of this study was to investigate the role of USP34 ...
Trends and Financial Burden of Gastrointestinal Stromal Tumors in the United States: A Comprehensive Analysis of United States Hospitalizations [0.03%]
美国胃肠间质瘤的流行趋势及经济负担分析：一项关于美国住院病人的全面分析
Sneh Sonaiya,Raj Patel,Charmy Parikh et al.
Sneh Sonaiya et al.
Background: Gastrointestinal stromal tumors (GISTs) are associated with a substantial economic burden to the healthcare system despite their relatively low incidence and prevalence compared to other more common malignanci...
Analysis of Adverse Events of Endoscopic Ultrasound-Guided Lumen-Apposing Metal Stent Placement: Insights Across Various Indications and Techniques [0.03%]
内镜超声引导的腔道间隔金属支架置入不良事件分析：不同适应症和技巧的见解
Mohammed Abusuliman,Taher Jamali,Faisal Nimri et al.
Mohammed Abusuliman et al.
Background: Endoscopic ultrasound (EUS)-guided lumen-apposing metal stent (LAMS) placement is increasingly being used in lieu of surgery for multiple procedures, including transmural fluid drainage. However, few studies h...
Think With Your Gut: A Retrospective Analysis on the Effects of Chronic Gastrointestinal Illness and Psychiatric Comorbidities [0.03%]
谨防病从口入：慢性胃肠疾病与精神疾病的相互作用机制及其应对策略回顾性分析
Rakahn Haddadin,Danny Aboujamra,Zachary I Merhavy et al.
Rakahn Haddadin et al.
Background: As mental health awareness increases, healthcare professionals must understand the interplay between chronic gastrointestinal (GI) conditions and psychological well-being, particularly regarding healthcare uti...
Treatment of Crohn's Disease With Infliximab and Subsequent Development of Takayasu's Arteritis [0.03%]
使用英夫利昔单抗治疗克罗恩病后发生泰 AKA榻尤氏动脉炎病例报告
Kei Nomura,Tomoyoshi Shibuya,Momoko Furusho et al.
Kei Nomura et al.
A 23-year-old man was diagnosed with Crohn's disease (CD) of the large intestine after colonoscopy revealed longitudinal ulcers, and pathology revealed non-caseating epithelioid cell granulomas and anal fistulas. The CD relapsed, and theref...
Case Reports
Gastroenterology research. 2024 Dec;17(5-6):217-223. DOI:10.14740/gr1792 2024
Rakahn Haddadin,Steven Molina,George Trad et al.
Rakahn Haddadin et al.
Background: Alcohol dependence remains a significant global health issue, exacerbated by the coronavirus disease 2019 (COVID-19) pandemic. Phosphatidylethanol (PEth), a direct biomarker of recent alcohol consumption, offe...
Risk Factors Predicting Outcomes in Advanced Upper Gastrointestinal Cancers Treated With Immune Checkpoint Inhibitors [0.03%]
预测免疫检查点抑制剂治疗晚期消化道肿瘤疗效的危险因素分析
Ashish Manne,Fode Tounkara,Eric Min et al.
Ashish Manne et al.
Background: Immune checkpoint inhibitors (ICIs) have moved to the frontline in recent years to manage upper gastrointestinal (UGI) tumors, such as esophageal and gastric cancers. This retrospective review sheds light on r...
Adult-Onset Autoimmune Enteropathy Mimicking Disaccharidase Deficiency [0.03%]
以双糖酶缺乏为表现的成人自身免疫性小肠病一例
Georgeta Giblen,Jerry Huang,Brandon Yu et al.
Georgeta Giblen et al.
Adult-onset autoimmune enteropathy is a rare disorder characterized by severe diarrhea, weight loss, malnutrition, and enteric mucosal atrophy resulting from immune-mediated injury. Disaccharidase deficiencies are a group of disorders chara...
Case Reports
Gastroenterology research. 2024 Aug;17(4):189-193. DOI:10.14740/gr1737 2024
Effect of Pemafibrate on the Lipid Profile, Liver Function, and Liver Fibrosis Among Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease [0.03%]
Pemafibrate对代谢功能障碍相关肝脂肪变性的影响：脂质谱、肝功能和肝纤维化
Mona Hassan,Hasan Al-Obaidi,Megan Karrick et al.
Mona Hassan et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) are prevalent conditions linked to obesity and metabolic disturbances, with potentia...
Pre-Cut Papillotomy Versus Endoscopic Ultrasound-Rendezvous for Difficult Biliary Cannulation: A Systematic Review and Meta-Analysis [0.03%]
困难胆道插管的预切乳头肌切开术与内镜超声联合选择性胰胆管造影：系统回顾和 meta 分析
Amna Iqbal,Zohaib Ahmad,Muhammad Aziz et al.
Amna Iqbal et al.
Background: Various endoscopic techniques are employed to achieve biliary cannulation when confronted with difficult biliary access. Every procedure carries its own risk in terms of bleeding, infection, pancreatitis, and ...