Efficacy and Safety of Tofacitinib for Acute Severe Ulcerative Colitis: A Systematic Review and Meta-Analysis [0.03%]
托法替尼治疗急性重度溃疡性结肠炎疗效和安全性的系统评价和 meta 分析
Gregory Brennan,Gilmara Coelho Meine,Lucas Monteiro Delgado et al.
Gregory Brennan et al.
Background: Acute severe ulcerative colitis (ASUC) is associated with a high risk of colectomy. About 30% of patients do not respond to steroids, requiring rescue therapy. This study aims to evaluate the efficacy and safe...
Jun Young Lee,Hyo-Yung Yun,Dae Hoon Kim et al.
Jun Young Lee et al.
Background: Acetylcholine (ACh), a crucial neurotransmitter for gastric contractions, induces triphasic contraction in stomach. However, the precise mechanism of ACh-induced phasic contractions (AiPCs) remains unclear. Re...
Histologic Assessment in Ulcerative Colitis: A Survey of Pathologists' Practices and Perspectives [0.03%]
溃疡性结肠炎的病理学评估：病理学家实践和观点调查
Krithika D Shenoy,Jiannan Li,Adam L Booth et al.
Krithika D Shenoy et al.
Background: Histologic remission is increasingly recognized as an important endpoint in ulcerative colitis (UC) management. Consensus guidelines on adopting histologic scoring systems in clinical practice are lacking in t...
Predictors of Development of Hepatocellular Carcinoma in Non-Cirrhotic Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease/Metabolic Dysfunction-Associated Steatohepatitis - A Retrospective Analysis of the National Inpatient Sample Database [0.03%]
非肝硬化患者中代谢紊乱相关肝脂肪变性/ steatohepatitis发生肝细胞癌的预测因素——全美住院样本数据库的回顾性分析
Samyak Dhruv,Shravya Ginnaram,Audrey Fonkam et al.
Samyak Dhruv et al.
Background: One-quarter of the world population is thought to have metabolic dysfunction-associated steatotic liver disease (MASLD). The incidence of metabolic dysfunction-associated steatohepatitis (MASH) and MASLD is ra...
Risk Stratification and Contemporary Predictors of Survival in Hepatocellular Carcinoma Treated With Transarterial Radioembolization [0.03%]
肝癌行经导管动脉放射栓塞治疗的生存预测因素及风险分层研究
Deepak Sherpally,Parthib Das,Fode Tounkara et al.
Deepak Sherpally et al.
Background: Identifying risk factors for poor outcomes in patients with hepatocellular carcinoma (HCC) treated with transarterial radioembolization (TARE) can aid in developing personalized management strategies, such as ...
Characterizing Patterns of Care for Diverticulitis Within the Contemporary Health System [0.03%]
当代医疗系统中憩室炎治疗模式的特征研究
Hyung C Kim,Vikram Anand,Jennifer A Kaplan et al.
Hyung C Kim et al.
Background: Diverticulitis is a common colon pathology that contributes a significant healthcare burden due to hospitalizations, colonoscopies, and operations. Although recent clinical practice guidelines (CPGs) advocate ...
Alcoholic Cirrhosis in the Hispanic Population of the United States: A Retrospective Analysis [0.03%]
美国Hispanic人群酒精性肝硬化的回顾性分析
Samyak Dhruv,Kuldeepsinh P Atodaria,Don C Rockey et al.
Samyak Dhruv et al.
Background: The Hispanic population is the fastest-growing ethnic group in the USA and is projected to comprise 30% of the US population by 2050. Despite socioeconomic disadvantages and often presenting with more severe d...
Enabling Drug-Induced Liver Injury Surveillance Through Automated Medication Extraction From Clinical Notes: A Medical Information Mart for Intensive Care IV Real-World Large Language Models Validation Study [0.03%]
通过自动从临床记录中提取药物进行肝损伤监测的医疗信息密集护理IV真实世界大型语言模型验证研究
Thanathip Suenghataiphorn,Kanachai Boonpiraks,Vitchapong Prasitsumrit et al.
Thanathip Suenghataiphorn et al.
Background: Drug-induced liver injury (DILI) presents a significant diagnostic challenge, often leading to delayed detection. Unstructured clinical notes contain comprehensive medication data vital for DILI surveillance b...
Efficacy of Potassium-Competitive Acid Blockers in Functional Dyspepsia: A Systematic Review and Meta-Analysis [0.03%]
钾竞争性酸阻滞剂治疗功能性消化不良的疗效：系统评价和 meta 分析
Hao The Nguyen,Arman Vaghefi,Tassawwar Khan
Hao The Nguyen
Background: Functional dyspepsia (FD) is a prevalent gastrointestinal disorder characterized by upper abdominal discomfort, often refractory to standard acid suppression therapy. Potassium-competitive acid blockers (PCABs...
Clinicopathological Features of KRAS-Mutated Colon Cancer: An Analytical Cross-Sectional Study [0.03%]
KRAS基因突变型结肠癌的临床病理特征分析横断面研究
Edgar Joaquin Cortes-Torres,Heli Hernandez-Gonzalez,Kathia Dayana Morfin-Meza et al.
Edgar Joaquin Cortes-Torres et al.
Background: Colon cancer is a leading neoplasm worldwide, with 35% to 45% of colorectal cancer (CRC) patients exhibiting mutations in the Kirsten rat sarcoma oncogene (KRAS). This mutation affects disease development and ...