Socioeconomic Deprivation Does Not Influence Disease Severity or Access to Dupilumab in Eosinophilic Esophagitis [0.03%]
社会经济剥夺不会影响嗜酸性食管炎的疾病严重程度或Dupilumab的获取能力
Fatema Ali,Dong Xi
Fatema Ali
Background: Studies have explored the relationship between eosinophilic esophagitis (EoE) and various factors such as race, gender, and geographic elements, including urbanization, population density, and climate zones. H...
A Supervised, Online, Home-Based Eccentric Resistance Exercise Program for Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease [0.03%]
代谢功能异常相关脂肪肝病患者的监督式、居家偶联阻力锻炼方案
Kedar S Deshpande,Kazunori Nosaka,Aus Molan et al.
Kedar S Deshpande et al.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common non-communicable chronic liver disease worldwide, increasing long-term risk of cirrhosis, type 2 diabetes mellitus, and cardi...
Trends and Impact of Clostridioides difficile Infection on Thirty-Day Readmissions and Outcomes Following Coronary Artery Bypass Grafting: A Seven-Year National Analysis [0.03%]
艰难梭菌感染对冠状动脉旁路移植术后30天再入院率和长期结局的影响：一项为期七年的全国性分析
Abhin Sapkota,Ninda Sherpa,Maria Grba et al.
Abhin Sapkota et al.
Background: Clostridioides difficile infection (CDI) is a common hospital-acquired infection, particularly seen among patients who undergo coronary artery bypass grafting (CABG). This study aimed to assess the trends and ...
Risk Factors for Mortality in Patients With Strangulating Intestinal Obstruction Who Present With Septic Disseminated Intravascular Coagulation Prior to the Initiation of Treatment [0.03%]
发病时即出现脓毒性弥散性血管内凝血的肠绞窄性肠梗阻患者影响死亡率的因素分析
En Amada,Yoshihiro Watanabe
En Amada
Background: Strangulating ileus is a life-threatening surgical emergency characterized by intestinal ischemia and necrosis due to impaired blood flow and is frequently complicated by septic disseminated intravascular coag...
Acyl-CoA Synthetase Long-Chain Family Member 4 in Liver Injury: Multidimensional Regulation and Therapeutic Potential [0.03%]
肝损伤中的长链酰基辅酶a合成酶家族成员4：多维度调控与治疗潜力
Ming Xing Liang,Mao Yi Wang,Yu Zhi Su et al.
Ming Xing Liang et al.
Acyl-CoA synthetase long-chain family member 4 (ACSL4) is a key enzyme that catalyzes the conjugation of long-chain fatty acids with coenzyme A to form acyl-CoA, showing particularly high specificity for polyunsaturated fatty acids. In rece...
Clinical Efficacy of Early and Late Vedolizumab or Infliximab Interventions in Moderate Ulcerative Colitis: A Multicenter, Retrospective Cohort Study [0.03%]
早期和晚期使用 vedolizumab 或 infliximab 治疗中度溃疡性结肠炎的临床疗效：一项多中心回顾性队列研究
Rui Ping Meng,Jian Zhang,Hao Qi Wei et al.
Rui Ping Meng et al.
Background: Late biologic intervention has been partly displaced during the last decade by early biologic therapy. However, there is a scarcity of direct evidence to inform clinical decision-making with greater confidence...
Early Therapeutic Response Predicts Outcome in Chronic Constipation: A Multicenter Prospective Observational Study [0.03%]
早期治疗反应能够预测慢性便秘患者的预后情况：一项多中心前瞻性观察研究
Tadayuki Oshima,Seiji Futagami,Yoshimasa Tanaka et al.
Tadayuki Oshima et al.
Background: Chronic constipation, common in clinical practice, requires treatment to enhance quality of life and possibly extend life expectancy. However, predictors of treatment efficacy remain largely unexplored. This s...
The Impact of Chronic Pancreatitis Etiology on Clinical Outcomes: A Population-Based Propensity-Matched Analysis [0.03%]
慢性胰腺炎病因对临床结局的影响：基于人群的倾向匹配分析
Khaled Elfert,Mohammed Abusuliman,Mohamed Eldesouki et al.
Khaled Elfert et al.
Background: Chronic pancreatitis (CP) is a complex disease with various underlying etiologies, including alcohol consumption, smoking, autoimmune disorders, genetic predispositions, and other less common causes. Despite e...
Global Prevalence of Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis [0.03%]
全球范围内肠易激综合症的发病率：一项最新的系统回顾及meta分析研究
Jhosmer Ballena-Caicedo,Lupita Ana Maria Valladolid-Sandoval,Fiorella E Zuzunaga-Montoya et al.
Jhosmer Ballena-Caicedo et al.
Background: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by abdominal pain and alterations in bowel habits. Previous studies show variability in its prevalence according to region...
HFE-C282Y/C282Y Hemochromatosis Patients Have Lower Serum Transferrin and Strong Negative Correlations Between Iron, Ferritin, and Transferrin Saturation Versus Transferrin Compared With HFE-wt/wt Wild-Type Subjects [0.03%]
HFE-C282Y/C282Y 血色素沉着病患者血清转铁蛋白较低且铁、 ferritin 和转铁蛋白饱和度与转铁蛋白之间呈强负相关，而野生型受试者则不然
Nils Thorm Milman
Nils Thorm Milman
Background: HFE-C282Y/C282Y hemochromatosis patients have lower serum transferrin levels than normal individuals, but the reason for this discrepancy has drawn little scientific attention and remains unclarified. The obje...