KCa3.1 Promotes the Migration of Macrophages From Epicardial Adipose Tissue to Induce Vulnerability to Atrial Fibrillation During Rapid Pacing [0.03%]
钾钙比值3.1促进心外膜脂肪组织中巨噬细胞迁移诱导快速起搏下房颤易感性增高
Yuanjia Ke,Zhen Cao,Xuewen Wang et al.
Yuanjia Ke et al.
Background: The relationship between local epicardial adipose tissue (EAT) macrophages and atrial fibrillation (AF) remains unclear. The purpose of this study was to investigate the role of KCa3.1 in the migration of macr...
Toward Earlier Diagnosis and Intervention for Patients With Aortic Stenosis in Canada [0.03%]
加拿大主动脉瓣狭窄患者的早期诊断和干预
Quynh Nguyen,Jessica G Y Luc,Jamil Bashir
Quynh Nguyen
Novel Genes Associated With Atrial Fibrillation and the Predictive Models for AF Incorporating Polygenic Risk Score and PheWAS-Derived Risk Factors [0.03%]
房颤相关新基因及包含多基因风险评分和基于PheWAS衍生危险因素的房颤预测模型
Shih-Yin Chen,Yu-Chia Chen,Ting-Yuan Liu et al.
Shih-Yin Chen et al.
Background: Atrial fibrillation (AF), the most common atrial arrhythmia, presents with varied clinical manifestations. Despite the identification of genetic loci associated with AF, particularly in specific populations, r...
Catheter Ablation for Atrial Fibrillation in Elderly Patients: an Updated Meta-analysis of Comparative Studies [0.03%]
经导管消融治疗老年房颤患者：比较研究的meta分析更新
Andreas A Boehmer,Moritz Rothe,Christian Ruckes et al.
Andreas A Boehmer et al.
Background: Age is a relevant risk factor for the development of atrial fibrillation (AF) and is associated with increased recurrence rates in the setting of rhythm control. Catheter ablation is increasingly advocated in ...
Instantaneous Right Ventricular to Pulmonary Artery Systolic Pressure Difference in Cardiac Surgery: A Retrospective and Prospective Cohort Study [0.03%]
心脏手术中心室收缩期压力差的即刻变化：回顾性和前瞻性队列研究
Etienne J Couture,Alexander Calderone,Yu Hao Zeng et al.
Etienne J Couture et al.
Background: During cardiac surgery, right ventricular outflow tract obstruction (RVOTO) is defined as an instantaneous pressure difference ≥ 6 mm Hg between right ventricular systolic pressure (RVSP) and pulmonary artery...
Alan Bell,Nicholas Giacomantonio
Alan Bell
The Continuing Scourge of Atherosclerotic Cardiovascular Disease: Importance of Multidisciplinary and Innovative Person-Centred Approaches [0.03%]
动脉粥样硬化性心血管疾病的持续肆虐：多学科和创新的以患者为中心的方法的重要性
Alice Cheng,Morgan Krauter,Kerri-Anne Mullen et al.
Alice Cheng et al.
This article discusses the complex approach to managing atherosclerotic cardiovascular disease (ASCVD), focusing on person-centred care (PCC) to align treatment strategies with individual patient narratives, values, and preferences. It iden...
Dyslipidemia and the Current State of Cardiovascular Disease: Epidemiology, Risk Factors, and Effect of Lipid Lowering [0.03%]
脂代谢异常与心血管疾病现状：流行病学、危险因素及调脂治疗的影响
Liam R Brunham,Eva Lonn,Shamir R Mehta
Liam R Brunham
Ischemic heart disease and stroke are the leading causes of death worldwide. Herein we review the burden, epidemiology, and risk factors for atherosclerotic cardiovascular disease (ASCVD). The focus of this review is on the current state of...
Care Gaps and System Issues With Delivering Cardiovascular Risk Reduction and Lipid-Lowering Therapy in Secondary Prevention [0.03%]
二级预防中心血管风险降低和调脂治疗的执行缺陷及系统问题
Guillaume Marquis-Gravel,Sacha Bhatia,Vivien Brown et al.
Guillaume Marquis-Gravel et al.
This article examines the care gaps in lipid-lowering therapy for atherosclerotic cardiovascular disease (ASCVD), primarily focusing on discrepancies between recommended practices and actual clinical implementation. It provides an overview ...
Ruth McPherson,Najah Adreak,Abhinav Sharma
Ruth McPherson
In the primary and secondary prevention of atherosclerotic cardiovascular disease (ASCVD), statins are the primary pharmacologic intervention for ASCVD risk reduction. Statins have proven efficacy and safety in reducing cardiovascular event...