The critical role of muscularis macrophages in modulating the enteric nervous system function and gastrointestinal motility [0.03%]
肌层巨噬细胞在调控内脏神经系统功能和胃肠动力方面发挥关键作用
Egan L Choi,Negar Taheri,Yuebo Zhang et al.
Egan L Choi et al.
Macrophages are the originators of inflammatory compounds, phagocytic purifiers in their local environment, and wound healing protectors in oxidative environments. They are molded by the tissue milieu they inhabit, with gastrointestinal (GI...
Re-examination of therapeutic management of muscular dystrophies using a vascular smooth muscle-centered approach [0.03%]
从血管平滑肌角度重新评估肌肉萎缩症的治疗管理方法
Senthilkumar Preethy,Naoki Yamamoto,Shiro Osaza et al.
Senthilkumar Preethy et al.
In contrast to the long-standing focus on the pathophysiology of skeletal muscles in the hunt for a cure for Duchenne muscular dystrophy (DMD), we opine that the malfunctioning of dystrophin produced by vascular smooth muscle is a major con...
Direct active Fyn-paxillin interaction regulates vascular smooth muscle cell migration [0.03%]
Fyn与paxillin的直接相互作用调节血管平滑肌细胞迁移
Ying Zhang,Hiroko Kishi,Sei Kobayashi
Ying Zhang
Vascular smooth muscle cell (VSMC) migration plays an important role in cardiovascular diseases, including atherosclerotic plaque formation and restenosis after vascular intervention. The mechanisms involved in VSMC migration are complex an...
Garcinia buchananii stem bark extract and its bioactive constituents manniflavanone, GB-2 and buchananiflavanone attenuate intestinal inhibitory neuromuscular transmission [0.03%]
Garcinia buchananii茎皮提取物及其生物活性成分manniflavanone、GB-2和buchananiflavanone可减弱肠道抑制性神经肌肉传递
Savannah Patterson,Michael Elder Waters,Nancy Braman et al.
Savannah Patterson et al.
Garcinia buchananii stem bark extract (GBB), commonly used for treating diarrhea in Africa, triggers ectopic aboral contractions, causing inhibition of propulsive motility in the colon ex vivo. To determine whether or not these effects were...
Sex differences in the central regulation of colorectal motility in response to noxious stimuli [0.03%]
noxious刺激下大肠运动的中枢调节的性别差异研究
Kazuhiro Horii,Tomoya Sawamura,Natsufu Yuki et al.
Kazuhiro Horii et al.
Distinct sex differences in the prevalence and symptoms of abnormal bowel habits in patients with irritable bowel syndrome (IBS) have been reported. We have elucidated the sex differences in the regulation of colorectal motility via the cen...
Clinical characteristics and manometric findings of esophageal achalasia-a systematic review regarding differences among three subtypes [0.03%]
不同类型食管失迟缓症的临床及测压特征-系统性综述
Ryo Katsumata,Noriaki Manabe,Hiroyuki Sakae et al.
Ryo Katsumata et al.
Esophageal achalasia is classified into three subtypes according to manometric findings. Since several factors, including clinical characteristics and treatment response, have been reported to differ among the subtypes, the underlying patho...
Noriyuki Kaji,Masatoshi Hori
Noriyuki Kaji
The gastrointestinal (GI) tract is a vital organ that digests food, absorbs nutrients, and excretes waste. Normal GI motility is the basis for these functions. The interstitial cells of Cajal (ICC) in the GI muscularis layer promote GI moti...
Quercetin and resveratrol ameliorate nickel-mediated hypercontraction in isolated Wistar rat aorta [0.03%]
黄芩素和白藜芦醇改善分离的Wistar大鼠主动脉的镍介导的过度收缩
Shahnawaz Ahmad Wani,Luqman Ahmad Khan,Seemi Farhat Basir
Shahnawaz Ahmad Wani
Purpose: The ameliorative potential of quercetin and resveratrol on isolated endothelium-intact aortic rings incubated with nickel was examined. Method: ...
Hangekobokuto, a traditional Japanese herbal medicine, ameliorates postoperative ileus through its anti-inflammatory action [0.03%]
汉药消化方剂改善术后肠麻痹的抗炎作用
Mari Endo,Tetsuro Oikawa,Miki Tonooka et al.
Mari Endo et al.
Background/aims: Gastroprokinetic agents are used for patients with postoperative ileus (POI), and the Japanese traditional herbal medicine daikenchuto (DKT) is one such agent used in the clinical setting. POI is caused b...
Orchiectomy but not adjuvant-induced arthritis induces structural modifications in rat aortas [0.03%]
输精管切除术而不是佐剂性关节炎可引起大鼠主动脉结构改变
Agnaldo Bruno Chies,Maria Angélica Spadella,Carla Patrícia Carlos et al.
Agnaldo Bruno Chies et al.
Purpose: This study aimed to verify whether Adjuvant-Induced Arthritis (AIA) and/or Orchiectomy (ORX) modify the expression of the Nox1, Nox2 and Nox4 isoforms, the endothelial function or the structure of rat aortas. ...