Endocardial substrate mapping for monomorphic ventricular tachycardia ablation in ischemic and non-ischemic cardiomyopathy [0.03%]
缺血性和非缺血性心肌病室性心动过速消融的内膜瘢痕标测指导
Koji Fukuzawa,Akihiro Yoshida,Shinya Kubo et al.
Koji Fukuzawa et al.
We investigated the differences in the endocardial substrates between ischemic cardiomyopathy (ICM) and non-ICM (NICM) by using electro-anatomical mapping and pace-mapping. We studied 18 patients (ICM and NICM, 9 each) with monomorphic vent...
Reduced insulin signaling and endoplasmic reticulum stress act synergistically to deteriorate pancreatic beta cell function [0.03%]
胰岛素信号减弱和内质网应激协同恶化胰腺β细胞功能
Tomokazu Matsuda,Yoshiaki Kido,Tohru Uchida et al.
Tomokazu Matsuda et al.
The total pancreatic beta cell mass is reduced in individuals with type 2 diabetes. We analyzed the islets of leptin receptor-deficient (Lepr-/-) mice, a model animal for type 2 diabetes with obesity. The plasma insulin levels in Lepr-/- mi...
Case report: Iridium 192-health effects during 20 years after irradiation [0.03%]
案列报告：放射性照射后20年的健康效应-以铱192为例
Snezana Milacic,Jadranko Simic
Snezana Milacic
This Case Report has presented health effects of high level of irradiation with gamma rays from Ir 192m on the patient M. L. during 21 years after the accident. The main purpose of this investigation was to analyze long time consequences of...
Novel mutations in 21 patients with tuberous sclerosis complex and variation of tandem splice-acceptor sites in TSC1 exon 14 [0.03%]
21例结节性硬化症复合体患者的新型突变及TSC1外显子14串联供体剪接位点的变异
Teguh Haryo Sasongko,Mari Wataya-Kaneda,Keiko Koterazawa et al.
Teguh Haryo Sasongko et al.
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by epilepsy, mental retardation, skin lesions, and tumors in various organs. However, TSC is sometimes difficult to diagnose because of its broad phenotypic sp...
Effect of ground green tea drinking for 2 weeks on the susceptibility of plasma and LDL to the oxidation ex vivo in healthy volunteers [0.03%]
健康志愿者饮用绿茶对血浆和低密度脂蛋白易氧化性的影响研究
Syuzou Gomikawa,Yuichi Ishikawa,Wakako Hayase et al.
Syuzou Gomikawa et al.
Catechins in green tea have been shown to reduce a risk of coronary heart disease in epidemiological studies. Also, it has been reported catechins have hypolipidemic and antioxidant effects. Then, we investigated the effects of ground green...
Clinical Trial
The Kobe journal of medical sciences. 2008 May 23;54(1):E62-72. DOI: 2008
Measurement of platelet-derived microparticle levels in the chronic phase of cerebral infarction using an enzyme-linked immunosorbent assay [0.03%]
酶联免疫吸附测定法测定慢性期脑梗死患者血小板源性微颗粒水平
Toshihiko Shirafuji,Hirotoshi Hamaguchi,Fumio Kanda
Toshihiko Shirafuji
Assessment of platelet function is a critical component of the treatment and secondary prevention of cerebral infarction, and measurement of platelet-derived microparticle (PDMP) levels using flow cytometry may be a good indicator of platel...
Growth hormone stimulates mechano growth factor expression and activates myoblast transformation in C2C12 cells [0.03%]
生长激素刺激机械生长因子表达并激活C2C12细胞的肌母细胞转化
Mari Imanaka,Keiji Iida,Ayumi Murawaki et al.
Mari Imanaka et al.
Mechano growth factor (MGF) is an alternatively spliced variant of insulin-like growth factor-I (IGF-I). Previous reports have revealed that the MGF in skeletal muscles is induced by mechanical overload or muscle injury. In the present stud...
Taurine administration after appearance of proteinuria retards progression of diabetic nephropathy in rats [0.03%]
补 tau 肽防治糖尿病肾小球病变的作用研究
Satomi Higo,Satoshi Miyata,Qing Yun Jiang et al.
Satomi Higo et al.
Oxidative stress has been postulated to be involved in the development of diabetic nephropathy. In the present study, we evaluated the effect of taurine, an endogenous antioxidant, on diabetic nephropathy by mixing it with the daily drinkin...
Preclinical safety pharmacology study of a novel protein-based cancer vaccine CHP-NY-ESO-1 [0.03%]
新型蛋白类抗肿瘤疫苗CHP-NY-ESO-1的安全药理学研究
Naozumi Harada,Kiyotaka Hoshiai,Yoshiyasu Takahashi et al.
Naozumi Harada et al.
CHP-NY-ESO-1 is a novel therapeutic cancer vaccine consisting of a recombinant protein of cancer antigen NY-ESO-1 and a polysaccharide-based delivery system, cholesteryl pullulan. A pilot clinical study of CHP-NY-ESO-1 in cancer patients wa...
Insulin-induced GLUT4 movements in C2C12 myoblasts: evidence against a role of conventional kinesin motor proteins [0.03%]
胰岛素诱导的C2C12肌细胞GLUT4运动：传统动力蛋白不起作用的证据
Kazuo Takazawa,Tetsuya Noguchi,Tetsuya Hosooka et al.
Kazuo Takazawa et al.
Insulin induces translocation of the glucose transporter GLUT4 from intracellular storage compartment to the plasma membrane via complex mechanisms that require intact cytoskeletal networks. In cultured adipocytes, conventional kinesin moto...