A Quinoline Derivative HZ-6d Induces Antiviral Activity Against Hepatitis C Virus Via Apoptosis-Mediated Cytotoxicity [0.03%]
喹啉衍生物HZ-6d通过凋亡诱导抗HCV活性
Gede Ngurah Rsi Suwardana,Aulia Fitri Rhamadianti,Takayuki Abe et al.
Gede Ngurah Rsi Suwardana et al.
We previously demonstrated that interferon-stimulated gene 15 protein (ISG15) plays a role in enhancing hepatitis B virus (HBV) and hepatitis C virus (HCV) infections through the ISGylation of the HBV X protein (HBx) and the HCV NS5A protei...
Hepatitis C Virus NS5A Inhibits YAP1-HSC70 Interaction, Thereby Preventing YAP1 Degradation Via Chaperone-Mediated Autophagy [0.03%]
丙型肝炎病毒NS5A通过抑制YAP1-HSC70相互作用来阻止YAP1经分子伴侣介导的自噬降解
Maria Alethea Septianastiti,Chieko Matsui,Zihan Xu et al.
Maria Alethea Septianastiti et al.
Hepatitis C virus (HCV) infection induces chaperone-mediated autophagy (CMA), where the HCV NS5A protein promotes the binding of the molecular chaperone HSC70 to substrate proteins containing a KFERQ motif. HSC70 recognizes this pentapeptid...
Apolipoprotein B48 as a Marker of Residual Coronary Risk: Diagnostic Insights from a Comparative Analysis with Ankle-Brachial Index [0.03%]
以载脂蛋白B48作为冠状动脉余留风险的标志物：与踝臂指数比较分析的诊断启示
Kenta Mori,Asuka Monobe,Sadatsugu Okuma et al.
Kenta Mori et al.
Apolipoprotein B48 (ApoB48) may be an indicator of residual cardiovascular risk beyond conventional lipid measures. However, its performance for detecting coronary artery disease (CAD), alone and in combination with the ankle-brachial index...
Comparative Study
The Kobe journal of medical sciences. 2025 Oct 21;71(3):E110-E123. DOI:10.24546/0100497875 2025
Developmental Outcomes at Ages 3-5 among Very-low and Extremely-low-birthweight Children without Major Complications Assessed at 18-24 Months [0.03%]
极低和超低出生体重但评估时无重大并发症的幼儿（18至24月龄）的发育结局（3～5岁）
Noriko Yamaoka,Satoshi Takada
Noriko Yamaoka
Around 9.4% of infants born in Japan have a low birthweight. While some studies have clarified the developmental progress of very-low-birthweight (VLBW) and extremely-low-birthweight (ELBW) infants at 18 months, less is known about how thes...
284 nm UVB Phototherapy Regulates Immunoinflammatory Responses and Improves Atherosclerotic Plaque Stability in Mice [0.03%]
284nm UVB光疗法通过调节免疫炎症反应改善小鼠动脉粥样硬化斑块稳定性
Ken Ito,Naoto Sasaki,Aga Krisnanda et al.
Ken Ito et al.
Aim: We previously reported that broad-band and specific wavelengths of ultraviolet B (UVB) limit the development of atherosclerosis by augmenting anti-inflammatory immune responses in hypercholesterolemic mice. This stud...
The Incidence of Abemaciclib-induced Interstitial Lung Disease: A Single-center Retrospective Study in Japan [0.03%]
一项在日本单中心进行的阿贝西利诱导的间质性肺病发生率的回顾性研究
Takeshi Hashimoto,Haruna Nakamura,Yoko Sakoda et al.
Takeshi Hashimoto et al.
Background and aim: Abemaciclib, a CDK4/6 inhibitor, is used for estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer. Interstitial lung disease (ILD) is a frequent adver...
Phase II Protocol on the Safety and Nutritional Status of Postoperative Enteral Nutrition Using HINEX® E-gel LC in Patients with Esophageal Cancer Undergoing Minimally Invasive Esophagectomy [0.03%]
HINEX®E-gelLC营养液在食管癌微创切除术后肠内营养中应用的安全性及营养状况的II期临床试验方案
Takashi Kato,Hironobu Goto,Michiko Takahashi et al.
Takashi Kato et al.
Background: Enteral nutrition therapy in the early postoperative period is essential for patients with esophageal cancer following esophagectomy. HINEX® E-gel LC is an oligomeric formula with various nutrients, including...
Chiharu Mishima,Kimikazu Yakushijin,Hidenori Fukuoka et al.
Chiharu Mishima et al.
We report a rare case of pseudohypercalcemia associated with multiple myeloma in a 77-year-old woman. Despite elevated albumin-corrected calcium levels (12.6 mg/dL), ionized calcium levels remained normal (1.25 mmol/L). Differential diagnos...
A Pregnant Woman with Primary Hyperparathyroidism Who Underwent Parathyroidectomy in the Second Trimester of Her Third Pregnancy: A Case Report [0.03%]
一例妊娠期原发性甲状旁腺功能亢进经手术治疗的病例报告
Masayuki Tanaka,Hitomi Imafuku,Iroha Kubota et al.
Masayuki Tanaka et al.
Primary hyperparathyroidism (PHPT) during pregnancy is rare, causing severe pregnancy complications. We report a pregnant woman with PHPT and a pregnancy complication history who underwent a single-gland parathyroidectomy during the second ...
Effects of Systemic and Skeletal Muscle-Specific Overexpression of Piezo1 [0.03%]
Piezo1全身及骨骼肌特异性过表达对其生理功能的影响
Tomoya Inoue,Tomoko Nishigaki,Yu Hirata et al.
Tomoya Inoue et al.
Piezo1, a mechanosensitive ion channel that opens in response to mechanical stimuli, is widely expressed among mammalian cell types, and regulates a diverse range of physiological processes. Although evidence has suggested potential clinica...