11,12-Epoxyeicosatrienoic Acid Attenuates Adipose Inflammation in Diet-Induced Obese Mice [0.03%]
11,12-环氧二十碳三烯酸通过减弱饮食诱导的肥胖小鼠的脂肪组织炎症来改善胰岛素抵抗
Huichen Zhao,Xiaoli Ma,Xiaocheng Yan et al.
Huichen Zhao et al.
Epoxyeicosatrienoic acids (EETs), the epoxidation products of arachidonic acid, were shown to have vasodilation and anti-inflammatory activity in many tissues. In the present study, the roles and mechanisms of EETs in the development of inf...
A Retrospective Study of the Association between Low Vitamin B1 in the Blood and Cognitive Impairment in Patients with Alzheimer's Disease [0.03%]
维生素B1缺乏与阿尔茨海默病患者认知功能障碍的相关性回顾性研究
Yuji Higaki,Yu Kobayashi
Yuji Higaki
This retrospective observational study investigated the association between low vitamin B1 (VB1) levels and cognitive impairment in 77 Japanese patients with Alzheimer's disease (AD). Multivariable regression analysis identified a significa...
Observational Study
Journal of nutritional science and vitaminology. 2025;71(5):421-426. DOI:10.3177/jnsv.71.421 2025
Differential Regulation of Cholecystokinin Production by Synthetic and Natural Glucocorticoids in Enteroendocrine Cells [0.03%]
肠内分泌细胞中合成型和天然型糖皮质激素对胆囊收缩素产生的差异化调节作用
Shingo Nakajima,Shoko Tsuchimine,Tohru Hira et al.
Shingo Nakajima et al.
Chronic stress often causes abnormal eating behavior and metabolism due at least in part to the activation of hypothalamic-pituitary-adrenal (HPA) axis resulting in increases glucocorticoids secretion. Cholecystokinin (CCK) is an anorexic g...
Effects of Combined Tunicamycin and a High-Fat Diet Rich in Saturated Fatty Acids on the Development of Steatohepatitis [0.03%]
联合使用童子裤和高饱和脂肪酸的高脂饮食对诱发 steatohepatitis的影响
Chie Takahashi-Muto,Rieko Tanaka-Yachi,Chikako Kiyose
Chie Takahashi-Muto
Non-alcoholic fatty liver disease (NAFLD) is influenced by various factors including diet, genetic predisposition, adipocytokines, oxidative stress and endoplasmic reticulum (ER) stress. In this study, we examined how pre-feeding mice a hig...
Tomofumi Yatsu,Momoka Koyama,Yoshiki Miyata
Tomofumi Yatsu
Age-related cataracts (ARC) are a leading cause of blindness worldwide, with lens epithelial cell (LEC) senescence playing a key role in their progression. While oxidative stress and DNA damage are known to induce LEC senescence, the mechan...
Shin Nishiumi,Tatsuo Nakahara,Mei Kimura et al.
Shin Nishiumi et al.
Rhizopus oligosporus (R. oligosporus) is a fungus belonging to the Mucoraceae and is usually used to ferment soybeans in East Asia. R. oligosporus-fermented soybeans are called tempeh and are mainly eaten in East Asia. The recent researches...
Brazilian Green Propolis Regulates Thermogenesis via Two Distinct Pathways [0.03%]
巴西绿蜂胶通过两种不同的途径调节产热作用
Takuma Hyodo,Nobuaki Okumura,Takanori Tsuda
Takuma Hyodo
Brazilian green propolis (BGP), produced by honey bees, induces beige adipocyte formation and accelerates whole-body energy metabolism. Artepillin C (ArtC), the major cinnamic acid derivative of BGP, induces beige adipocyte formation and in...
Potential of Tomato Seed Extract for Wrinkle Care through Human Neutrophil Elastase Inhibition: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial [0.03%]
Tomomi Degawa,Shogo Takeda,Norihito Shimizu et al.
Tomomi Degawa et al.
Numerous cosmetic products claim to improve aging-induced wrinkles, and recent research has explored the potential of oral intake for wrinkle improvement. In our previous study, we investigated the effects of tomato seed extract (TSE), whic...
Randomized Controlled Trial
Journal of nutritional science and vitaminology. 2025;71(4):366-374. DOI:10.3177/jnsv.71.366 2025
Effects of Oligonol® Supplementation on Abdominal Fat in Japanese Overweight Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study [0.03%]
oligonol 对日本超重受试者腹部脂肪影响的随机、双盲、安慰剂对照试验
Jun Takanari,Manami Misu,Kazunori Goto et al.
Jun Takanari et al.
Obesity is known to induce diabetes, hypertension, and dyslipidemia, and reducing obesity is important from the perspective of disease prevention. Oligonol, a standardized oligomerized-polyphenol from Litchi chinensis fruit extract, is expe...
Randomized Controlled Trial
Journal of nutritional science and vitaminology. 2025;71(4):357-365. DOI:10.3177/jnsv.71.357 2025