Genealogical characterization of regional populations and dorsal coat color variation in the house mouse Mus musculus from Asia based on haplotype structure analysis of a gene-rich region harboring Mc1r [0.03%]
基于Mc1r基因位点的单倍体型结构分析鉴定亚洲小家鼠的地方种群及其毛色变异
Kazuhiro Zakoh,Kazumichi Fujiwara,Toyoyuki Takada et al.
Kazuhiro Zakoh et al.
We analyzed 196 haplotype sequences from a gene-rich region (250 kb) that includes Mc1r, a gene involved in coat color regulation, to gain insight into the evolution of coat color variation in subspecies of the house mouse Mus musculus. Phy...
Ancient standing genetic variation facilitated the adaptive radiation of Lake Victoria cichlids [0.03%]
古老的遗传变异促进了维多利亚湖丽鱼的适应性演化radiation原文中出现了多个关键词，分别是"adaptive radiation"和"standing genetic variation"。根据生物学知识，“adaptive radiation”指的是一个群体快速分化成多个生态位不同的物种的现象；“standing genetic variation”指现存群体中的所有遗传多样性。综合这些信息，最终翻译为“古老的遗传变异促进了维多利亚湖丽鱼的适应性演化”。
Haruna Nakamura,Mitsuto Aibara,Masato Nikaido
Haruna Nakamura
Cichlid fishes are textbook examples of explosive speciation and adaptive radiation, providing a great opportunity to understand how the genomic substrate yields extraordinary species diversity. Recently, we performed comparative genomic an...
N-terminal acetyltransferase NatB regulates Rad51-dependent repair of double-strand breaks in Saccharomyces cerevisiae [0.03%]
酵母N末端乙酰化酶NatB通过调节Rad51依赖的DNA双链损伤修复维持基因组稳定性
Natsuki Sugaya,Shion Tanaka,Kenji Keyamura et al.
Natsuki Sugaya et al.
Homologous recombination (HR) is a highly accurate mechanism for repairing DNA double-strand breaks (DSBs) that arise from various genotoxic insults and blocked replication forks. Defects in HR and unscheduled HR can interfere with other ce...
Comprehensive analysis of downstream transcriptomic features in the competitive relationships between BEH3 and other BES/BZR transcription factors [0.03%]
BEH3与其他BES/BZR转录因子竞争关系的下游转录组特征综合分析
Tomoyuki Furuya,Yuki Kondo
Tomoyuki Furuya
Members of a plant-specific BES/BZR transcription factor (TF) family including BRI1-EMS-SUPPRESSOR 1 (BES1) and BRASSINAZOLE-RESISTANT 1 (BZR1) regulate various developmental processes and environmental responses. Recently, we reported that...
Promoter generation for the chimeric sex-determining gene dm-W in Xenopus frogs [0.03%]
异种性别决定基因dm-W启动子在非洲爪蟾中的构建
Shun Hayashi,Kei Tamura,Daisuke Tsukamoto et al.
Shun Hayashi et al.
Many sex-determining genes (SDGs) were generated as neofunctionalized genes through duplication and/or mutation of gonadal formation-related genes. We previously identified dm-W as an SDG in the African clawed frog Xenopus laevis and found ...
The role of conserved amino acid residues of Sae3 in Mei5-Sae3 complex for Dmc1 assembly in meiotic recombination [0.03%]
Sae3保守性氨基酸残基在Mei5-Sae3复合体中对Dmc1在减数重组中的装配所起的作用
Priyanka Sawant,Stephen Mwaniki,Yurika Fujita et al.
Priyanka Sawant et al.
Meiotic recombination between homologous chromosomes is promoted by the collaborative action of two RecA homologs, Rad51 and meiosis-specific Dmc1. The filament assembly of Dmc1 is promoted by meiosis-specific Mei5-Sae3 in budding yeast. Me...
Genetic structure and population history of a peat swamp forest tree species, Shorea albida (Dipterocarpaceae), in Brunei Darussalam [0.03%]
文莱淡豹树（豆科淡豹树属）的遗传结构及其种群历史研究
Misato Ogasahara,Alexander R Cobb,Rahayu Sukmaria Sukri et al.
Misato Ogasahara et al.
Southeast Asia supports high biodiversity, in a mosaic of forest types formed by the expansion and contraction of habitats through past climate changes. Among the region's forest types, the geographical distribution of peat swamp forests ha...
Hiroaki Shimada,Katsunori Tanaka
Hiroaki Shimada
Posttranslational modifications (PTMs) to proteins are regulatory mechanisms that play a critical role in regulating growth and development. The SUMO system is a rapid and dynamic PTM system employed by eukaryotic cells. Plant SUMOs are inv...
Differential expression profile of miRNAs between stable and vulnerable plaques of carotid artery stenosis patients [0.03%]
狭窄患者稳定与不稳定的颈动脉斑块差异miRNA表达谱分析
Ying Deng,Shuai Jiang,Xueguang Lin et al.
Ying Deng et al.
Plaque vulnerability is associated with the degree of carotid artery stenosis (CS) and the risk of stroke. MicroRNAs (miRNAs) exert critical functions in disease progression, although only a few miRNAs have been well identified in CS. There...
Masayuki Seki
Masayuki Seki
Mechanisms underlying how the genetic code was generated by Darwinian selection have remained elusive since the code was cracked in 1965. Here, I propose a hypothesis on the emergence of the genetic code and predict that its emergence was d...