Regulation of nitric oxide generation by up-regulated arginase I in rat spinal cord injury [0.03%]
大鼠脊髓损伤后精氨酸酶I上调抑制一氧化氮生成的机制研究
Takashi Imagama,Keiki Ogino,Kei Takemoto et al.
Takashi Imagama et al.
Recently, arginase is suggested to regulate nitric oxide production by competing with nitric oxide synthase for the same substrate, L-arginine, in experimental asthma. We investigated the role of arginase and its relationship to nitric oxid...
(±)Equol inhibits invasion in prostate cancer DU145 cells possibly via down-regulation of matrix metalloproteinase-9, matrix metalloproteinase-2 and urokinase-type plasminogen activator by antioxidant activity [0.03%]
雌烯醇通过抗氧化作用下调基质金属蛋白酶-9、基质金属蛋白酶-2和尿激酶型纤溶酶原激活剂抑制前列腺癌DU145细胞侵袭性生长
Wei Zheng,Yumei Zhang,Defu Ma et al.
Wei Zheng et al.
Exposure to soy isoflavones has been associated with low mortality of prostate cancer. In this study, we examined the effects of (±)equol and two representative isoflavones, daidzein and genistein, on migration and invasion in human prosta...
All-trans Arachidonic acid generates reactive oxygen species via xanthine dehydrogenase/xanthine oxidase interconversion in the rat liver cytosol in vitro [0.03%]
全反式花生四烯酸通过黄嘌呤脱氢酶/黄嘌呤氧化酶相互转化在体外生成活性氧物种
Satoru Sakuma,Takahiro Kitamura,Chihiro Kuroda et al.
Satoru Sakuma et al.
We previously reported that the all-cis isomer of arachidonic acid, the most naturally occurring isoform of this fatty acid, reduced cuprous copper ion-induced conversion of xanthine dehydrogenase into its reactive oxygen species generating...
Begum Tutuncu,Vural Kuçukatay,Sevki Arslan et al.
Begum Tutuncu et al.
The aim of this study was to investigate the possible effects of sulphite oxidase (SOX, E.C. 1.8.3.1) deficiency on xenobiotic metabolism. For this purpose, SOX deficiency was produced in rats by the administration of a low molybdenum diet ...
Astaxanthin prevents changes in the activities of thioredoxin reductase and paraoxonase in hypercholesterolemic rabbits [0.03%]
虾青素预防家兔高胆固醇血症的抗氧化防御系统改变
Paula R Augusti,Andréia Quatrin,Sabrina Somacal et al.
Paula R Augusti et al.
This study explored the effects of the antioxidant astaxanthin on paraoxonase and thioredoxin reductase activities as well as on other oxidative stress parameters and on the lipid profile in hypercholesterolemic rabbits. Rabbits were fed a ...
Takafumi Senmaru,Michiaki Fukui,Muhei Tanaka et al.
Takafumi Senmaru et al.
Atrophic gastritis is characterized by chronic inflammation of gastric mucosa by Helicobacter pylori infection and other factors. Helicobacter pylori infection has been linked to coronary artery disease. To our knowledge, however, no report...
Partially hydrolyzed guar gum affects the expression of genes involved in host defense functions and cholesterol absorption in colonic mucosa of db/db male mice [0.03%]
部分水解瓜尔胶影响db/db雄性小鼠结肠粘膜中宿主防御功能和胆固醇吸收相关基因的表达
Zenta Yasukawa,Yuji Naito,Tomohisa Takagi et al.
Zenta Yasukawa et al.
Biomedical evidence in the last 20 years has shown that the consumption of partially hydrolyzed guar gum may influence lipid and/or carbohydrate metabolism at many levels. Since intestine represents the first interface to interact with diet...
Dietary phosphate restriction ameliorates endothelial dysfunction in adenine-induced kidney disease rats [0.03%]
饮食限磷改善腺嘌呤致肾病大鼠内皮功能障碍的影响
Tan Vu Van,Eriko Watari,Yutaka Taketani et al.
Tan Vu Van et al.
Hyperphosphatemia causes endothelial dysfunction as well as vascular calcification. Management of serum phosphate level by dietary phosphate restriction or phosphate binders is considered to be beneficial to prevent chronic kidney disease p...
Inhibition of deprivation-induced food intake by GABA(A) antagonists: roles of the hypothalamic, endocrine and alimentary mechanisms [0.03%]
GABA(A)受体拮抗剂抑制剥夺引起的摄食作用：下丘脑、内分泌和消化机制的作用
Ganesan L Kamatchi,Palaniswami Rathanaswami
Ganesan L Kamatchi
The role of gamma amino butyric acid A receptors/neurons of the hypothalamic, endocrine and alimentary systems in the food intake seen in hunger was studied in 20 h food-deprived rats. Food deprivation decreased blood glucose, serum insulin...
Effects of rice bran oil on the blood lipids profiles and insulin resistance in type 2 diabetes patients [0.03%]
米糠油对2型糖尿病患者血脂谱和胰岛素抵抗的影响研究
Ming-Hoang Lai,Yi-Ting Chen,Ya-Yen Chen et al.
Ming-Hoang Lai et al.
The aim of this study was to investigate the influence of rice bran oil consumption on plasma lipids and insulin resistance in patients with type 2 diabetes. Thirty-five patients with type 2 diabetes were randomly assigned to a placebo grou...