Critical Role of microRNA-33a/b in Cardiovascular and Metabolic Disease: Molecular Mechanisms and Therapeutic Perspectives [0.03%]
microRNA-33a/b在心血管和代谢性疾病中的关键作用：分子机制与治疗前景
Takahiro Horie,Osamu Baba,Tomohiro Nishino et al.
Takahiro Horie et al.
MicroRNAs (miRNAs) serve as fundamental post-transcriptional regulators of gene expression, among which the miR-33 family, consisting of miR-33a and miR-33b, has emerged as a critical modulator in the pathogenesis of cardiovascular and meta...
Prevalence of the JAK2 V617F Mutation in Patients with Non-Cardioembolic Stroke [0.03%]
非心源性卒中患者JAK2 V617F突变的患病率
Naoki Oyama,Tomoko Okazaki,Hitoshi Miura et al.
Naoki Oyama et al.
Aim: This study attempted to clarify the prevalence and clinical characteristics of Janus kinase 2 V617F (JAK2) gene mutations in patients with cerebrovascular diseases. ...
Chronic Limb-Threatening Ischemia in Patients Undergoing Hemodialysis: Epidemiology, Risk Factors, and Outcomes [0.03%]
血液透析患者的慢性肢体缺血的流行病学、危险因素及结局
Chieko Komaba,Hirotaka Komaba,Kotaro Imagawa et al.
Chieko Komaba et al.
Aims: Chronic limb-threatening ischemia (CLTI) is a serious complication in patients with kidney failure. We aimed to investigate the frequency and clinical burden of CLTI in patients undergoing hemodialysis. ...
Chlamydia pneumoniae Seropositivity is Associated with Cardiovascular Events in the General Population: The Nagahama Study [0.03%]
肺炎衣原体阳性与一般人群心血管事件相关：奈加哈玛研究
Aya Ogawa,Aya Shoji-Asahina,Takahisa Kawaguchi et al.
Aya Ogawa et al.
Aims: Persistent Chlamydia pneumoniae (C. pneumoniae) infection has been suggested to be a risk factor for cardiovascular events; however, only findings from studies on small populations are available so far. This study i...
Clinical Significance of Adjusting the Estimated Glomerular Filtration Rate by an Individual's Body Surface Area from the Perspective of the Cardio-ankle Vascular Index: A Cross-sectional Study [0.03%]
基于心血管踝压指数校正个体体表面积的肾小球滤过率估计值的临床意义：横断面研究
Daiji Nagayama,Yasuhiro Watanabe,Masahiro Ohira et al.
Daiji Nagayama et al.
Aim: A decline in the estimated glomerular filtration rate (eGFR) is associated with vascular dysfunction, a cardiovascular disease (CVD) risk. However, since the eGFR is based on the standard body surface area (BSA) of 1...
Evinacumab Improved the Homozygous Familial Hypercholesterolemia Lipid Metabolism: A Case Report [0.03%]
艾伐他单抗改善同型家族高胆固醇血症的脂质代谢：一例报告
Takaaki Matsuda,Yoshinori Osaki,Nako Matsumoto et al.
Takaaki Matsuda et al.
Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by high levels of low-density lipoprotein cholesterol (LDL-C) and increased risk of early onset atherosclerosis. Evinacumab, an angiopoietin-like prote...
Pemafibrate Increases Circulating Angiopoietin-like Proteins 3 and 4 Without Promoting Pro-Atherogenic Changes in LDL and HDL Subspecies: A Post-Hoc Analysis of the PRESTIGE Study [0.03%]
贝法司他通过后 hoc 分析增加循环血管生成素样蛋白3和4而不促进PRESTIGE研究中的LDL和HDL亚型的促动脉粥样硬化变化
Tsutomu Hirano,Toshiyuki Hayashi,Hiroe Sugita et al.
Tsutomu Hirano et al.
Aims: Angiopoietin-like proteins (ANGPTLs) are key regulators of lipid metabolism; however, their response to lipid-lowering therapies remains incompletely understood. The PRESTIGE study compared the effects of pemafibrat...
From Risk to Resilience: Transforming Perinatal Management for Women with FH [0.03%]
从风险到韧性：转化妊娠期FH患者的管理方案
Masatsune Ogura
Masatsune Ogura
Prognostic Value of the HELT-E2S2 Score in Patients with Lower Extremity Artery Disease and a Comparison with the Atrial Fibrillation and Lower Extremity Artery Disease Scores: Insight from the I-PAD NAGANO Registry [0.03%]
HELT-E2S2评分对下肢动脉疾病患者预后的预测价值及其与房颤和下肢动脉疾病评分的比较：I-PAD NAGANO登记处的见解
Yoshiteru Okina,Tatsuya Saigusa,Yasushi Ueki et al.
Yoshiteru Okina et al.
Aims: The HELT-E2S2 score is a newly developed risk stratification tool for stroke in patients with atrial fibrillation. We investigated the prognostic value of the HELT-E2S2 score in patients with lower extremity artery ...
When Fat Speaks: Decoding the Signals of Epicardial Adipose Tissue after Acute Coronary Syndrome [0.03%]
心包脂肪组织的声音：急性冠脉综合征后 epicardial 脂肪组织信号的解读
Takashi Morinaga,Atsushi Tanaka,Koichi Node
Takashi Morinaga