Neonatal bilateral whisker trimming in male mice age-dependently alters brain neurotransmitter levels and causes adolescent onsets of social behavior abnormalities [0.03%]
新生鼠双侧须切除术雄性小鼠年龄依赖性地改变脑内神经递质水平并导致青春期社会行为异常发生
Hiroyasu Murasawa,Hitomi Soumiya,Hiroyuki Kobayashi et al.
Hiroyasu Murasawa et al.
Tactile perception via whiskers is important in rodent behavior. Whisker trimming during the neonatal period affects mouse behaviors related to both whisker-based tactile cognition and social performance. However, the molecular basis of the...
A point of view on human fat olfaction - do fatty derivatives serve as cues for awareness of dietary fats? [0.03%]
人体脂肪嗅觉的观点-脂肪衍生物能否作为感知膳食脂肪的信号分子？
Satoshi Tsuzuki
Satoshi Tsuzuki
Fat (triglycerides) consumption is critical for the survival of animals, including humans. Being able to smell fat can be advantageous in judging food value. However, fat has poor volatility; thus, olfaction of fat seems impossible. What ab...
Red foxtail millet upregulates brain-derived neurotrophic factor levels in vitro and in vivo [0.03%]
红曲米可上调脑源性神经营养因子的表达水平
Kensuke Nakajima,Hayato Tomohiro,Shigeru Oiso
Kensuke Nakajima
Upregulation of the brain-derived neurotrophic factor (BDNF) in the brain can help in the prevention and treatment of depression. BDNF is synthesized in various peripheral tissues, as well as in the brain, and can reach the brain via the bl...
Anatomical basis of gastrin- and CCK-secreting cells and their functions. A review [0.03%]
胃泌素和胆囊收缩素分泌细胞的解剖学基础及其功能综述
Toshihiko Iwanaga
Toshihiko Iwanaga
Gastrin and CCK (cholecystokinin), gut hormones first secreted after postprandial stages, share the C-terminal amino acids and some types of receptors to be stimulated. Both types of hormone-secreting cells are typical open-type cells which...
The effect of the formalin-fixed paraffin-embedded process on salivary microbiota profiling [0.03%]
福尔马林固定石蜡包埋工艺对口腔微生物群谱分析的影响
Hiroto Sano,Takuichi Sato,Yoriaki Kanri et al.
Hiroto Sano et al.
In recent years, bacterial DNA in formalin-fixed paraffin-embedded (FFPE) samples has been recognized as a valuable bioresource for microbiota studies. This study aimed to examine the effect of the FFPE process on microbiota profiling to ev...
The lncRNA ADAMTS9-AS1/miR-185-5p/KAT7 ceRNA network inhibits cardiomyocyte hypertrophy in hypertrophic obstructive cardiomyopathy [0.03%]
长链非编码RNA ADAMTS9-AS1/miR-185-5p/KAT7竞争性内源RNA网络可抑制肥厚型梗阻性心肌病中心肌细胞肥大
Bangrong Song,Wei Li,Xiaoyu Xu et al.
Bangrong Song et al.
Hypertrophic obstructive cardiomyopathy (HOCM) is a well-recognized inherited cardiac disease. This study was conducted to explore the role of lncRNA ADAMTS9 antisense RNA 1 (ADAMTS9-AS1) in HOCM-induced cardiomyocyte hypertrophy. The serum...
Sasa veitchii extracts protect phenytoin-induced cell proliferation inhibition in human lip mesenchymal cells through modulation of miR-27b-5p [0.03%]
萨斯维奇提取物通过调节miR-27b-5p保护苯妥英抑制人唇间充质细胞增殖
Yosuke Tsukiboshi,Aya Ogata,Azumi Noguchi et al.
Yosuke Tsukiboshi et al.
A cleft lip, with or without a cleft palate, is a common birth defect caused by environmental factors or genetic mutations. Environmental factors, such as pharmaceutical exposure in pregnant women, are known to induce cleft lip, with or wit...
Immunohistochemical characterization of the mandibular condyle for type I and II collagen, aggrecan, MMP-9, and MMP-13 in MMP-2-deficient mice [0.03%]
MMP-2缺陷型小鼠下颌关节软骨中I、II型胶原、aggrecan和基质金属蛋白酶-9及-13的免疫组化定位研究
Mu-Chen Yang,Megumi Nakamura,Miyuki Mayanagi et al.
Mu-Chen Yang et al.
Mice devoid of matrix metalloproteinase (MMP)-2 due to gene targeting have been reported to show articular cartilage destruction in the knee joint; however, the phenotype of the mandibular condylar cartilage remains unknown. Thus, in the pr...
Role of aquaporin 5 and glandular blood flow in the acetylcholine-induced secretion of saliva in rats [0.03%]
胆碱诱发的大鼠唾液分泌中水通道蛋白5和腺体血流的作用
Mst Tahmina Akter,Akihiro Nezu,Tetsuya Akamatsu et al.
Mst Tahmina Akter et al.
To clarify the role of the aquaporin 5 (AQP5) in salivary secretion, we evaluated acetylcholine (ACh)-induced secretion in Sprague-Dawley (SD) rats, rats expressing a low level of AQP5 protein (AQP5/low SD) which developed from SD rats, and...
Cannabinoid receptors involved in descending inhibition on spinal seizure-like activity in the phrenic output [0.03%]
参与调控脊髓呼吸中枢痫样放电的下行抑制性投射及大麻素受体的作用机制研究
Shih Tien Lin,Makito Iizuka,Yoshihiro Mikami et al.
Shih Tien Lin et al.
Seizure-like burst activities are induced by blockade of GABAA and/or glycine receptors in various spinal ventral roots of brainstem-spinal cord preparation from neonatal rodents. We found that this is not applicable to the phrenic nerve an...