Dissecting the Roles of Innate Cells in the Skin and Intractable Skin Diseases [0.03%]
皮肤免疫细胞在难治性皮肤病中的作用机制
Keisuke Chris Nagao
Keisuke Chris Nagao
The skin is not merely a physical barrier but also an active immunological interface, exposed to various external stimuli including microbes. Over the recent years, our laboratory has defined hair follicles as control towers that regulates ...
Brain-machine Interface (BMI)-based Neurorehabilitation for Post-stroke Upper Limb Paralysis [0.03%]
基于脑机接口(BMI)的卒中后上肢瘫痪神经康复训练
Meigen Liu,Junichi Ushiba
Meigen Liu
Because recovery from upper limb paralysis after stroke is challenging, compensatory approaches have been the main focus of upper limb rehabilitation. However, based on fundamental and clinical research indicating that the brain has a far g...
Serum Neurogranin Measurement as a Biomarker of Central Nervous System Infections: A Preliminary Study [0.03%]
神经粒素作为中枢神经系统感染生物标志物的价值：初步研究
Isil Bektas Canturk,Asim Kalkan,Acelya Kirat Es et al.
Isil Bektas Canturk et al.
The early diagnosis of central nervous system infections is of great importance to minimize morbidity and mortality. Neurogranin is a postsynaptic neural protein, and when the blood-brain barrier is damaged, neurogranin levels increase in b...
Molecular mechanisms of building blocks of life towards medicinal applications [0.03%]
生命分子构件的医药应用机制研究
Osamu Nureki
Osamu Nureki
Membrane and membrane-spanning proteins, and non-coding RNA are biomolecules to play central roles in beginning of life and distinguishing higher-order eukaryotes. We have determined the structures of membrane protein-lipids complexes and n...
Katalin Karikó
Katalin Karikó
Messenger RNA was discovered in 1961 and it took 60 years until the first mRNA became FDA-approved product in the form of COVID-19 mRNA vaccine. During those years a lot of progress has been made by hundreds of scientists. It was 1978 when ...
Food Protein-induced Enterocolitis Syndrome Due to Rice in a Japanese Infant: A Case Report [0.03%]
日本婴儿因食用大米引起的食物蛋白诱导性肠炎综合征病例报告
Hiroshi Hayashi,Naoki Kajita,Koichi Yoshida et al.
Hiroshi Hayashi et al.
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated gastrointestinal food allergy characterized by repetitive vomiting within 1-4 h and/or diarrhea within 24 h after ingesting the causative food. We herein report a rar...
A Theory of Diagnostic Testing to Stop the Virus Spreading: Evidence-based Reasoning to Resolve the COVID-19 Crisis by Testing [0.03%]
基于证据的推理解决COVID-19危机的检测理论模型及验证
Isao Kamae
Isao Kamae
In this study, the complicated reasoning and processes inherent in diagnostic testing were analyzed, and a mathematical theory was developed for effectively stopping the transmission of infection in the context of coronavirus disease 2019 (...
Metabolism in Human Pluripotent Stem Cells and Cardiomyocytes for Regenerative Therapy [0.03%]
用于再生医学的人类多能干细胞和心肌细胞的代谢研究
Tomohiko C Umei,Shugo Tohyama
Tomohiko C Umei
Pluripotent stem cells (PSCs), which include embryonic stem cells and induced pluripotent stem cells, have the potential for unlimited self-renewal and proliferation and the ability to differentiate into all three embryonic germ layers. Hum...
Keio Uterus Transplantation Research: From Basic Research toward Future Clinical Application [0.03%]
Keio子宫移植研究：从基础研究到未来的临床应用
Iori Kisu,Kouji Banno,Yusuke Matoba et al.
Iori Kisu et al.
Uterus transplantation (UTx) is now a potential option to allow women with uterine factor infertility to give birth. However, UTx is still at an experimental stage, and basic animal studies, including in non-human primates, are needed for t...
Diagnostic Performance of Computed Tomography Imaging for COVID-19 in a Region with Low Disease Prevalence [0.03%]
计算机断层扫描在低新冠肺炎发病率地区诊断中的表现
Ho Lee,Tatsuya Suzuki,Yohei Okada et al.
Ho Lee et al.
Coronavirus disease 2019 (COVID-19) was first reported in Wuhan, China, in December 2019 as an outbreak of pneumonia of unknown origin. Previous studies have suggested the utility of chest computed tomography (CT) in the diagnosis of COVID-...