Masayuki Akashi
Masayuki Akashi
Food protein-induced enterocolitis syndrome (FPIES) is a type of non-IgE-mediated gastrointestinal food allergy. FPIES is characterized by repetitive vomiting without classic IgE-mediated allergic skin or respiratory symptoms 1-4 h after ca...
Reoperative Aortic Valve Replacement for Structural Valve Deterioration through a Lower Hemisternotomy after a Previous Bentall Procedure in a Patient with Tracheostomy [0.03%]
之前接受过Bentall手术的气管切开术患者经下部半胸骨劈开术治疗主动脉瓣置换术后结构瓣衰败
Kaori Katsumata,Yujiro Kawai,Tsutomu Ito et al.
Kaori Katsumata et al.
Patients with tracheostomy who undergo a full sternotomy have an increased risk of mediastinitis and sternal infection. This report describes a reoperative aortic valve replacement (re-AVR) for structural valve deterioration (SVD) through a...
Age Group Differences in Daily Life Changes among Community Residents during the COVID-19 Pandemic: A Pilot Study on Intergenerational Comparison [0.03%]
COVID-19疫情期间社区居民日常生活变化的年龄差异：一项代际比较的初步研究
Natsuki Yamamoto-Takiguchi,Eiko Uchiyama,Hiroki Fukahori et al.
Natsuki Yamamoto-Takiguchi et al.
This study investigated lifestyle changes and the self-reported mental health status of Japanese community residents during the COVID-19 pandemic. Differences in demography, daily lifestyle changes, and approaches to problem solving were an...
Shinya Sugimoto,Eiji Kobayashi,Takanori Kanai et al.
Shinya Sugimoto et al.
Our understanding of the biology of the intestinal epithelium has advanced since the establishment of an organoid culture system. Although organoids have enabled investigation of the mechanism of self-renewal of human intestinal stem cells ...
Targeting Tumor Microenvironment in Liver Cancers: Rationale, Current Progress, and Future Perspective [0.03%]
肝癌肿瘤微环境治疗的理性思考、现状及未来展望
Dan G Duda
Dan G Duda
Surgical treatments offer the chance for cure in primary or metastatic liver cancers. However, many patients experience disease progression after surgical interventions, or cannot undergo surgery as they present with unresectable disease at...
Dissecting the Roles of Innate Cells in the Skin and Intractable Skin Diseases [0.03%]
皮肤免疫细胞在难治性皮肤病中的作用机制
Keisuke Chris Nagao
Keisuke Chris Nagao
The skin is not merely a physical barrier but also an active immunological interface, exposed to various external stimuli including microbes. Over the recent years, our laboratory has defined hair follicles as control towers that regulates ...
Brain-machine Interface (BMI)-based Neurorehabilitation for Post-stroke Upper Limb Paralysis [0.03%]
基于脑机接口(BMI)的卒中后上肢瘫痪神经康复训练
Meigen Liu,Junichi Ushiba
Meigen Liu
Because recovery from upper limb paralysis after stroke is challenging, compensatory approaches have been the main focus of upper limb rehabilitation. However, based on fundamental and clinical research indicating that the brain has a far g...
Serum Neurogranin Measurement as a Biomarker of Central Nervous System Infections: A Preliminary Study [0.03%]
神经粒素作为中枢神经系统感染生物标志物的价值：初步研究
Isil Bektas Canturk,Asim Kalkan,Acelya Kirat Es et al.
Isil Bektas Canturk et al.
The early diagnosis of central nervous system infections is of great importance to minimize morbidity and mortality. Neurogranin is a postsynaptic neural protein, and when the blood-brain barrier is damaged, neurogranin levels increase in b...
Molecular mechanisms of building blocks of life towards medicinal applications [0.03%]
生命分子构件的医药应用机制研究
Osamu Nureki
Osamu Nureki
Membrane and membrane-spanning proteins, and non-coding RNA are biomolecules to play central roles in beginning of life and distinguishing higher-order eukaryotes. We have determined the structures of membrane protein-lipids complexes and n...
Katalin Karikó
Katalin Karikó
Messenger RNA was discovered in 1961 and it took 60 years until the first mRNA became FDA-approved product in the form of COVID-19 mRNA vaccine. During those years a lot of progress has been made by hundreds of scientists. It was 1978 when ...