Aseptic Meningitis after BNT-162b2 COVID-19 Vaccination: Case Report and Literature Review [0.03%]
BNT162b2新型冠状病毒疫苗接种后无菌性脑脊髓炎一例及文献复习
Yuji Kato,Takashi Osada,Nobuo Araki et al.
Yuji Kato et al.
We encountered a-27-year-old female patient who developed refractory severe headache and photophobia after the first dose of COVID-19 vaccine. Despite her prior history of migraine, we diagnosed COVID-19 vaccine-induced aseptic meningitis. ...
Yuichi Yoshida
Yuichi Yoshida
Neurofibromatosis 1 (NF1), also known as von Recklinghausen disease, is one of the most common neurocutaneous genetic disorders. Loss of function of the NF1 gene results in overactivation of the RAS/MAPK pathway, leading to neurocutaneous m...
Tatsuhiro Masaoka
Tatsuhiro Masaoka
Constipation is a complicated condition. Chronic constipation is diagnosed when constipation occurs for more than 3 months. Chronic constipation is classified using patient symptoms and the pathophysiology. New therapeutic agents to treat c...
Hiroyuki Goto,Chiharu Tateishi,Daisuke Tsuruta
Hiroyuki Goto
Gorlin syndrome and Cowden syndrome are hereditary diseases that are characterized by multiple malignancies, cutaneous symptoms, and various other abnormalities. Both disorders are caused by a mutation of the gene that regulates cell prolif...
Tuberous Sclerosis Complex [0.03%]
结节性硬化症综合征
Mari Wataya-Kaneda
Mari Wataya-Kaneda
Tuberous sclerosis complex (TSC) is an autosomal dominant inherited disease characterized by systemic hamartomas, neuropsychiatric symptoms known as TAND (TSC-associated neuropsychiatric disorders), and vitiligo. These symptoms are attribut...
Kenta Maruyama
Kenta Maruyama
The sensory and immune systems have been studied independently for a long time, whereas the interaction between the two has received little attention. We have carried out research to understand the interaction between the sensory and immune...
Yutaka Shimomura
Yutaka Shimomura
The hair follicle is an appendage of the skin that undergoes hair cycles throughout life. Recently, numerous genes expressed in the hair follicles have been identified, and variants in some of these genes are now known to underlie hereditar...
Recent Advances in Clinical Research on Rare Intractable Hereditary Skin Diseases in Japan [0.03%]
日本难治性遗传性皮肤罕见病的临床研究新进展
Masashi Akiyama,Takuya Takeichi,Shigaku Ikeda et al.
Masashi Akiyama et al.
Our Research Group for Rare and Intractable Skin Diseases operates within the Project for Research on Intractable Diseases of the Ministry of Health, Labour, and Welfare of Japan and is conducting research on eight rare intractable skin dis...
Targeting DNA Methylation in Podocytes to Overcome Chronic Kidney Disease [0.03%]
靶向系膜细胞DNA甲基化以克服慢性肾脏疾病
Kaori Hayashi
Kaori Hayashi
The number of patients with chronic kidney disease (CKD) is on the rise worldwide, and there is urgent need for the development of effective plans against the increasing incidence of CKD. Podocytes, glomerular epithelial cells, are an integ...
Yoshihiro Kawaoka
Yoshihiro Kawaoka
Emerging infections are caused when microorganisms that are maintained in a reservoir where they cause no harm, transmit from the reservoir to a new host. I have been studying the replication, molecular basis for pathogenesis, and host resp...