Pancreatic Cancer in Hereditary Breast and Ovarian Cancer Syndrome: Is Early Detection Possible? [0.03%]
遗传性乳腺癌和卵巢癌综合症中的胰腺癌：早期检测有可能吗？
Kodai Abe,Minoru Kitago,Yusuke Kobayashi et al.
Kodai Abe et al.
A program of recruiting families with hereditary pancreatic cancer and hereditary breast and ovarian cancer (HBOC) syndrome as high-risk individuals for pancreatic cancer surveillance using magnetic resonance cholangiopancreatography (MRCP)...
Exploring Breast Cancer Risk Management in HBOC Patients: Image Surveillance Versus Risk-reducing Surgery [0.03%]
遗传性乳腺癌卵巢癌患者风险评估和管理的研究：影像监测与预防性手术的比较
Tomoko Seki,Yusuke Kobayashi,Kenta Masuda et al.
Tomoko Seki et al.
In Japan, the rising incidence of hereditary breast and ovarian cancer syndrome (HBOC) follows partial insurance coverage introduced in 2020. Compared with the general population (~11% lifetime risk), individuals with HBOC face a significan...
Poorly Differentiated Carcinoma with only Clear Glandular Differentiation Arising from the Bladder Trigone: A Case of Adenocarcinoma or Urothelial Carcinoma? [0.03%]
仅表现出明显腺体分化的分化不良的 carcinoma 起源于三角膀胱区：是一例腺癌或尿路上皮癌？
Kaoru Furihata,Atsushi Kurabayashi,Waka Iwashita et al.
Kaoru Furihata et al.
Invasive urothelial carcinoma (UC) has diverse morphological presentations. Here, we describe the case of a Japanese woman aged in her early 60s with UC with unclear differentiation. The patient presented with distinct glandular differentia...
Current Situation and Future Directions of Risk-reducing Salpingo-oophorectomy [0.03%]
预防性卵巢输卵管切除术的现状及未来方向
Kenta Masuda,Yusuke Kobayashi,Tomoko Seki et al.
Kenta Masuda et al.
High-grade serous carcinoma (HGSC), the most aggressive subtype of epithelial ovarian cancer, is strongly associated with hereditary breast and ovarian cancer (HBOC) syndrome and is primarily linked to germline BRCA1/2 pathogenic variants (...
Pioneering the Future of Cancer Immunotherapy: A New Era of Synthetic Immunology through Computational Modeling [0.03%]
开拓癌症免疫治疗的未来：通过计算建模进入合成免疫学的新时代
Taisuke Kondo
Taisuke Kondo
Chimeric Antigen Receptor (CAR) T-cell immunotherapy has revolutionized the treatment of hematological malignancies. However, its application to solid tumors has been hindered by poor specificity and potential toxicity to healthy tissues. T...
Identification of Issues Related to Enteral Nutrients Using a Database of Near-miss Events from Community Pharmacies [0.03%]
通过社区药房的近乎失误事件数据库识别肠内营养相关问题
Shingo Kondo,Mari Maese,Hiroki Iwata et al.
Shingo Kondo et al.
Undernutrition is a common risk after surgery or during periods when oral dietary intake is challenging. Enteral nutrients, frequently utilized in nutritional management, are drugs associated with multiple contraindications involving pathol...
Potential New Tumors Associated with Hereditary Breast and Ovarian Cancer (HBOC) [0.03%]
与遗传性乳腺癌和卵巢癌（HBOC）相关的潜在新肿瘤类型
Kohei Nakamura,Kenta Masuda,Tomoko Seki et al.
Kohei Nakamura et al.
Hereditary breast and ovarian cancer syndrome (HBOC) is traditionally associated with mutations in the BRCA1 and BRCA2 genes, predominantly impacting breast, ovarian, pancreatic, and prostate cancers. However, recent research suggests that ...
Mental Health Care among Cancer Patients with BRCA Gene Mutations: The Potential of Mindfulness-based Intervention [0.03%]
BRCA基因突变的癌症患者的的精神健康护理：基于正念干预的可能性
Mari Takeuchi,Sunre Park
Mari Takeuchi
Hereditary breast and ovarian cancer syndrome (HBOC) is a hereditary tumor syndrome caused by mutations in BRCA genes. Advances in genetic testing technologies have enabled surveillance and risk-reducing surgeries for carriers of BRCA mutat...
Intractable Pruritus as Initial Presentation of Cytomegalovirus -Tuberculosis Coinfections [0.03%]
难治性瘙痒作为巨细胞病毒感染-结核感染的首发症状
Shivnarayan Sahu,Priyavadhana Balasubramanian,Prasan Kumar Panda et al.
Shivnarayan Sahu et al.
Coinfection of cytomegalovirus (CMV) and Mycobacterium tuberculosis presenting with acquired perforating dermatosis is a rare occurrence and remains poorly described in the literature. A man in his 40s, a farmer and chronic smoker, who was ...
Unilateral Frosted Branch Angiitis Following COVID-19 Disease: Case Report and Literature Review [0.03%]
新型冠状病肺炎后发生的单侧冰霜分枝状角膜炎的病例报告及文献回顾
Asma Alzuabi,Abdulrahman Albloushi
Asma Alzuabi
Frosted branch angiitis (FBA) is a rare and aggressive form of retinal vasculitis that can cause vision loss. This condition is typically idiopathic and can be associated with various infections or malignancies. Recently, FBA has been linke...