Hypertrophic Cardiomyopathy: Diverse Pathophysiology Revealed by Genetic Research, Toward Future Therapy [0.03%]
肥厚型心肌病：基因研究揭示多样的病理生理机制，面向未来的治疗方向
Takeharu Hayashi
Takeharu Hayashi
Hypertrophic cardiomyopathy (HCM) is an intractable disease that causes heart failure mainly due to unexplained severe cardiac hypertrophy and diastolic dysfunction. HCM, which occurs in 0.2% of the general population, is the most common ca...
Body Motion and Rowing Performance: Association between Hip Angle and Rowing Performance: A Pilot Study [0.03%]
身体运动与划船表现：髋关节角度与划船表现之间的关联：一项初步研究
Masato Fumoto,Yasushi Sera,Koichiro Azuma et al.
Masato Fumoto et al.
The importance of aerobic fitness in rowing has been widely studied, and it is accepted that aerobic fitness is a key factor in rowing performance. In contrast, the impact of rowing efficacy, especially rowing form, on rowing performance ha...
Direct Cardiac Reprogramming for Cardiovascular Regeneration and Differentiation [0.03%]
心脏直接重编程在心血管再生与分化中的应用
Taketaro Sadahiro,Masaki Ieda
Taketaro Sadahiro
Cardiovascular disease is the leading cause of death worldwide. Cardiomyocytes have limited regenerative capacity; consequently, regenerative therapies are in high demand. There are currently several potential strategies for heart regenerat...
Tadamitsu Kishimoto
Tadamitsu Kishimoto
A series of our studies on IL-6 have revealed that it has a pleiotropic activity in various tissues and cells and its deregulated expression is responsible for several chronic inflammations and hemopoietic malignancies.Humanized antibody ag...
Hans C Clevers
Hans C Clevers
Stem cells are the foundation of all mammalian life. Stem cells build and maintain our bodies throughout life. Two types of stem cells are discerned.1) Embryonic stem cells (ES cells) are briefly present in the early human or mouse embryo, ...
Dr. Seiji Ogawa and the Past, Present, and Future of Functional MRI Research [0.03%]
Ogawa博士与功能磁共振成像研究的过去、现在和未来
Hideyuki Okano
Hideyuki Okano
Bernd Zetsche,Omar O Abudayyeh,Jonathan S Gootenberg et al.
Bernd Zetsche et al.
The class 2 CRISPR-Cas endonuclease Cas12a (previously known as Cpf1) offers several advantages over Cas9, including the ability to process its own array and the requirement for just a single RNA guide. These attributes make Cas12a promisin...
Louise Robinson
Louise Robinson
Dementia care currently costs the UK 21 bn pounds a year, and that doesn't include the huge informal costs of family careers and community support networks. Developing services to meet the needs of patients with complex health problems must...
Bas P L Wijnhoven
Bas P L Wijnhoven
In contrast to many other countries, training of medical specialists is funded by the Department of Health. The curriculum of medical specialist training including general surgery is well structured and lasts 6 years. Specialist (trainers) ...
Clinical Features of Febrile Urinary Tract Infection Caused by Extended-spectrum Beta-lactamase-producing Escherichia Coli in Children [0.03%]
儿童由超广谱β内酰胺酶大肠埃希菌所致发热性尿路感染的临床特征分析
Takuma Ohnishi,Yoshinori Mishima,Shohei Takizawa et al.
Takuma Ohnishi et al.
The global prevalence of infections caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli has been increasing. In children, ESBL-producing E. coli manifest mostly as febrile urinary tract infections (fUTIs). This stud...