Syndrome of Inappropriate Secretion of Antidiuretic Hormone Caused by Very Short-term Use of Proton Pump Inhibitor [0.03%]
质子泵抑制剂短期应用所致的抗利尿激素异常分泌综合征
Sae Aratani,Takeshi Matsunobu,Takahiro Kawai et al.
Sae Aratani et al.
Proton pump inhibitors (PPIs) are widely used medicines worldwide. However, a rare etiology of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) related to PPI was recently reported. Therefore, the putative role of PPIs in...
Antifungal Agent Luliconazole Inhibits the Growth of Mouse Glioma-initiating Cells in Brain Explants [0.03%]
抗真菌剂Luliconazole抑制脑组织移植物中鼠胶质母细胞瘤起始细胞的生长
Hideaki Nagashima,Naoyoshi Koike,Kazunari Yoshida et al.
Hideaki Nagashima et al.
Imidazole antifungal compounds exert their antipathogenic effects through inhibition of sterol biosynthesis. These drugs have also recently been identified as candidate anticancer agents for several solid tumors including glioblastoma. Howe...
Recent Advances in the Definition and Management of Functional Dyspepsia [0.03%]
近期关于功能性消化不良定义和治疗的进展
Hidekazu Suzuki
Hidekazu Suzuki
In 2016, the Rome criteria were updated as Rome IV, and only minor changes were introduced for functional dyspepsia (FD). The major symptoms of FD now include not only postprandial fullness, but also epigastric pain and burning, and early s...
Seitaro Fujishima
Seitaro Fujishima
Juntaro Matsuzaki,Takahiro Ochiya
Juntaro Matsuzaki
Early detection of cancer is crucial for its ultimate control and the prevention of malignant progression. In Japan, a nationwide project was conducted between 2014 and 2019 to develop novel cancer detection tools using serum microRNAs (miR...
Hypertrophic Cardiomyopathy: Diverse Pathophysiology Revealed by Genetic Research, Toward Future Therapy [0.03%]
肥厚型心肌病：基因研究揭示多样的病理生理机制，面向未来的治疗方向
Takeharu Hayashi
Takeharu Hayashi
Hypertrophic cardiomyopathy (HCM) is an intractable disease that causes heart failure mainly due to unexplained severe cardiac hypertrophy and diastolic dysfunction. HCM, which occurs in 0.2% of the general population, is the most common ca...
Body Motion and Rowing Performance: Association between Hip Angle and Rowing Performance: A Pilot Study [0.03%]
身体运动与划船表现：髋关节角度与划船表现之间的关联：一项初步研究
Masato Fumoto,Yasushi Sera,Koichiro Azuma et al.
Masato Fumoto et al.
The importance of aerobic fitness in rowing has been widely studied, and it is accepted that aerobic fitness is a key factor in rowing performance. In contrast, the impact of rowing efficacy, especially rowing form, on rowing performance ha...
Direct Cardiac Reprogramming for Cardiovascular Regeneration and Differentiation [0.03%]
心脏直接重编程在心血管再生与分化中的应用
Taketaro Sadahiro,Masaki Ieda
Taketaro Sadahiro
Cardiovascular disease is the leading cause of death worldwide. Cardiomyocytes have limited regenerative capacity; consequently, regenerative therapies are in high demand. There are currently several potential strategies for heart regenerat...
Tadamitsu Kishimoto
Tadamitsu Kishimoto
A series of our studies on IL-6 have revealed that it has a pleiotropic activity in various tissues and cells and its deregulated expression is responsible for several chronic inflammations and hemopoietic malignancies.Humanized antibody ag...
Hans C Clevers
Hans C Clevers
Stem cells are the foundation of all mammalian life. Stem cells build and maintain our bodies throughout life. Two types of stem cells are discerned.1) Embryonic stem cells (ES cells) are briefly present in the early human or mouse embryo, ...