Ligustilide Attenuates Neuroinflammation and Fibrosis in an Aluminum Chloride-induced Rat Model of Alzheimer's Disease via mTOR/STAT3 Signaling Inhibition [0.03%]
通过抑制mTOR/STAT3信号通路减弱神经炎症和纤维化从而改善氯化铝诱导的阿尔茨海默病模型的大豆素作用
Nizar Sirag,Hassabelrasoul Elfadil,Abduallh J Ghabban et al.
Nizar Sirag et al.
Alzheimer's disease (AD) affects approximately 50 million individuals worldwide and is projected to triple by 2050. Ligustilide is a naturally occurring compound with varied pharmacological actions. Ligustilide has been reported to ameliora...
Community Pharmacists' Attitudes and Experiences Regarding the Promotion of Vaccinations in Japan [0.03%]
日本药房从业人员关于推广疫苗的立场和经验研究
Hiroki Iwata,Taiki Kirihara,Noriko Kobayashi et al.
Hiroki Iwata et al.
Japan has the lowest vaccine confidence worldwide. Although community pharmacists are expected to support public health, it remains unclear whether Japanese community pharmacists-who cannot administer vaccines-engage in vaccine consultation...
Identifying High-Cost RSV Hospitalizations at a Secondary Hospital in Japan [0.03%]
在日本一家二级医院识别高成本的RSV住院治疗
Tomomi Matsuda,Yoshiko Seki,Masayuki Akashi et al.
Tomomi Matsuda et al.
Respiratory syncytial virus (RSV) is a leading cause of hospitalization in infants and young children worldwide. Although most RSV hospitalizations occur at secondary hospitals, information on RSV-related healthcare costs in these settings ...
Comparison of Clinical Development of Digital Therapeutics among Japan, the Unites States, and Germany [0.03%]
日本、美国和德国数字疗法的临床开发比较研究
Toshiyoshi Tominaga,Tomonobu Hasegawa,Eiji Harada
Toshiyoshi Tominaga
Digital therapeutics (DTx) have demonstrated promising potential as a novel therapeutic approach, with their clinical development gaining momentum. Comparison of DTx development between Japan, a relative newcomer, and Germany and the U.S., ...
Palliative Radiotherapy for Colorectal Villous Adenoma with Severe Diarrhea and Electrolyte Imbalance [0.03%]
严重腹泻及电解质紊乱的绒毛腺瘤的姑息性放疗
Hirofumi Toyama,Yoshihiro Nakazato,Yuka Katsurada et al.
Hirofumi Toyama et al.
Colorectal large villous adenomas are sometimes associated with McKittrick-Wheelock syndrome, a condition characterized by severe diarrhea leading to dehydration, electrolyte depletion, and acute renal failure, which can be life-threatening...
Chemotherapy for Breast Cancer with Pre-existing Cryptogenic Organizing Pneumonia: Epirubicin/cyclophosphamide Followed by Weekly Paclitaxel [0.03%]
原有原因不明的组织性肺炎患者乳腺癌的化疗--表阿霉素/环磷酰胺序贯 weekly paclitaxel治疗
Ouki Kuniyoshi,Yuta Yokoyama,Yuma Nonomiya et al.
Ouki Kuniyoshi et al.
The incidence of breast cancer in patients with pre-existing interstitial lung disease has been rarely reported. Consequently, evidence supporting the safety of chemotherapy in this population remains limited. This report describes the case...
Acceptability and Preliminary Effects of Online Evidence-based Practice Education Program for Undergraduate Nursing Students: A Pre- and Post-intervention Study [0.03%]
基于在线证据实践教育项目的本科生护理学生接受度及初步效果的干预前后研究
Sotaro Shimada,Ai Tomotaki,Ardith Z Doorenbos et al.
Sotaro Shimada et al.
Evidence-based practice (EBP) plays a crucial role in improving healthcare quality; however, there is still a lack of insight into EBP education for nursing in Japan. We aimed to evaluate the acceptability and preliminary effects of an onli...
Injury Prevalence and Associated Factors in Japanese Competitive Kendo Collegiate Athletes [0.03%]
日本竞武道大学生运动员的损伤流行病学及影响因素
Takeshi Kimura,Aleksandra Mącznik,Akira Kinoda et al.
Takeshi Kimura et al.
In Japan, many schools include kendo as part of the school physical education program. Farther afield, kendo also serves as a life-long method to improve and retain physical fitness and mental skills for adults of all ages around the world....
Analysis of the Stability of 0.04% Mitomycin C Ophthalmic Solution under Various Storage Conditions [0.03%]
0.04%丝裂霉素C滴眼液在不同储存条件下的稳定性研究分析
Yuma Nonomiya,Koki Yamaguchi,Yuta Yokoyama et al.
Yuma Nonomiya et al.
A 0.04% mitomycin C (MMC) ophthalmic solution is not commercially available and is prepared in hospitals as required. The physical properties and stability of the MMC ophthalmic solution have not been clarified because of a lack of data. Th...