Gastrointestinal Motility-Induced Interplay in Pancreas Proton Therapy: Motion Simulation and Dosimetric Impact [0.03%]
胃肠运动引起的胰腺质子治疗相互作用：运动模拟和剂量学影响
Jing Wang,Xingyi Zhao,Elissa Khoudary et al.
Jing Wang et al.
Purpose: To simulate motion and evaluate its dosimetric interplay from gastrointestinal (GI) motility in pancreas pencil-beam scanning (PBS) proton therapy, and to assess how fractionation and motility amplitude affect ta...
Intra-fractional Voxel-wise Anatomical Motion Tracking Guided by Multimodal Respiratory Surrogates in Radiotherapy: Framework Development and Multi-Center Validation [0.03%]
基于多模式呼吸替代物的放射治疗期间的亚分数 voxel 解剖运动跟踪：框架开发和多中心验证
Gongsen Zhang,Zejun Jiang,Yao Xu et al.
Gongsen Zhang et al.
Purpose: Intra-fractional respiratory motion management encounters trade-offs between target coverage, organ at risk (OAR) sparing, and treatment efficacy. Real-time tracking is promising but hindered by invasiveness risk...
A Gaussian-based planning approach for robust dose-escalated stereotactic body proton therapy [0.03%]
基于高斯分布的稳健剂量递增立体定向体部质子治疗计划设计方法
Xiandong Zhao,Thomas R Mazur,Hailei Zhang et al.
Xiandong Zhao et al.
Purpose: Proton plans are often very homogenous with minimal hotspots compared to the prescribed dose, which may not be ideal for ablative stereotactic body radiation therapy (SBRT). A treatment planning approach for ster...
Privacy-Preserving Virtual Contrast-enhanced MRI for Nasopharyngeal Carcinoma: A Multi-center Study [0.03%]
基于虚拟磁共振血管成像的鼻咽癌多中心隐私保护研究
Wen Li,Zhen Li,Yiming Shi et al.
Wen Li et al.
Purpose: Contrast-enhanced MRI imaging via administration of contrast agents is critical for diagnosis, staging, and treatment of nasopharyngeal carcinoma. However, gadolinium-based contrast agents can lead to severe adve...
Liver tumor motion and reconstructed doses in a clinical trial of respiratory gated proton therapy for hepatocellular carcinoma [0.03%]
呼吸门控质子治疗肝细胞癌临床试验中的肝脏肿瘤运动及重建剂量学研究
Saber Nankali,Esben Schjødt Worm,Jakob Borup Thomsen et al.
Saber Nankali et al.
Purpose: Pencil beam scanning proton therapy of hepatocellular carcinoma (HCC) may reduce the risk of radiation-induced liver disease compared to photon radiotherapy, but tumor motion and anatomical changes can distort th...
Local sinonasal and regional nodal effects of lymph node irradiation in a pilot study of dogs with naturally occurring sinonasal tumors [0.03%]
一项关于自然发生的鼻窦肿瘤的狗的试点研究中淋巴结照射的局部和区域结节效应
Mary-Keara Boss,Laurel B Darragh,Stavroula Georgiopoulou et al.
Mary-Keara Boss et al.
Purpose: Head and neck cancer patients with high risks for regional metastasis receive radiation therapy targeted to their primary tumor and regional lymph nodes (RLN). RLN irradiation may alter cancer immunity. We invest...
Cross-Institutional Validation of a novel LLM-Based Cardiac Event Extraction framework from Electronic Health Records [0.03%]
基于电子健康记录的新型LLM心脏事件提取框架的跨机构验证
Wenchao Cao,Isis Lloyd,Michael Dichmann et al.
Wenchao Cao et al.
Purpose: Cardiac toxicity is a significant concern for cancer patients undergoing radiotherapy. The complexity of evaluating cardiac events, the time required to parse the Electronic Health Record (EHR), and the need for ...
Cardiac Substructure Dosimetry and Major Adverse Cardiac Events After Breast Radiotherapy: A 12-Year Cohort Study with NTCP Modeling [0.03%]
乳腺放疗后的心脏亚结构剂量学和主要心血管事件：一项12年的队列研究及NTCP建模分析
Jeffrey C F Lui,Jeffrey C H Chan,James C H Chow et al.
Jeffrey C F Lui et al.
Purpose: To identify cardiac substructure dosimetric predictors of major adverse cardiac events (MACE) following breast radiotherapy, and to develop a robust normal tissue complication probability (NTCP) model for persona...
Laila A Gharzai,Yingzhe Alex Liu,Zequn Sun et al.
Laila A Gharzai et al.
Objective: Patients undergoing radiotherapy (RT) often face substantial out of pocket costs (OOPC), putting patients at risk of going into debt. Unpaid medical debt sent to collections is a proxy for severe financial dist...
External Beam Radiotherapy Primes PDL1-Targeted Radionuclide Therapy in Preclinical Colorectal Cancer Model [0.03%]
体外放射治疗可激发PD-L1靶向核素治疗：结直肠癌模型中的治疗增敏作用
Pierre-Simon Bellaye,Alexia Tavares,Riad Ladjohounlou et al.
Pierre-Simon Bellaye et al.
Purpose: Colorectal cancer (CRC) remains one of the most prevalent and lethal malignancies worldwide. Although external beam radiotherapy (RT) plays a growing role in primary and metastatic CRC, dose escalation may remain...