Multi-omics identification of ZFPM2 and CD44 as key candidates for testicular size in sheep [0.03%]
多组学识别ZFPM2和CD44作为绵羊睾丸大小的关键候选基因
Yangkai Liu,Jialei Chen,Yali Song et al.
Yangkai Liu et al.
Testicular size is a key determinant of ram fertility, yet its genetic architecture in sheep remains poorly understood. Crossbred sheep exhibit substantial testicular developmental variation and serve as ideal models for screening fertility...
Bulls carrying the myostatin genotype show impaired sperm cryotolerance [0.03%]
一种myostatin基因型公牛的精子冻精耐受性受损
Carolina Tamargo,Rodrigo Muiño,Elena N Matínez et al.
Carolina Tamargo et al.
While the myostatin (MSTN) gene is responsible for the double-muscled phenotype in cattle and has been associated with alterations in metabolism and energy homeostasis. its potential effects on sperm function and fertility remain poorly und...
Primordial germ cell transplantation into X-ray-sterilized roosters for viable chicken production: a pilot study [0.03%]
有关鸡胚移植的初步研究:将原始生殖细胞植入X射线辐射后的公鸡以产生可育后代
Lijuan Wang,Qiang Zheng,Jiaxin Sun et al.
Lijuan Wang et al.
Different approaches have been developed for producing viable chickens by transplanting primordial germ cells (PGCs) into recipients. Implanting PGCs into chicken embryos requires intricate techniques and results in low germline transmissio...
Exploring the postpartum period in mares: hormonal dynamics and ovarian activity under physiological and pathological conditions [0.03%]
探讨母马产褥期的内分泌动态及生理和病理条件下的卵巢活动
Francesca Perina,Aliai Lanci,Diana Fanelli et al.
Francesca Perina et al.
The aims of the study were to evaluate factors influencing the resumption of postpartum ovarian activity and to compare hormone concentrations among mares with physiological/pathological postpartum period and cyclic non-lactating mares. Fol...
Multi-omics analysis reveals that arginine protects porcine oocytes from heat stress induced deterioration [0.03%]
多组学分析揭示精氨酸通过保护猪卵母细胞免受热应激损害来改善卵母细胞质量
Guangjun Huang,Hongyu Sun,Fuyao Zhang et al.
Guangjun Huang et al.
Global warming induced heat stress severely impairs porcine oocyte quality due to their high lipid content, disrupting reproductive performance. This study combined transcriptomic and metabolomic analyses of heat-stressed porcine oocytes, i...
Nicotinamide improves bovine blastocyst quality and implantation potential by modulating matrix metalloproteinase expression [0.03%]
烟酰胺通过调节基质金属蛋白酶的表达改善牛囊胚质量和着床潜力
Marwa El-Sheikh,Ayman Mesalam,Seo-Hyun Lee et al.
Marwa El-Sheikh et al.
Nicotinamide (NAM), a precursor for nicotinamide adenine dinucleotide (NAD+), is widely used as a supplement during different cells culturing. Although its antioxidative and anti-apoptotic properties, the specific effects on bovine embryo q...
Pro-developmental role of AMPK-PINK1/Parkin-mediated mitophagy in the morula-to-blastocyst transition during early embryonic development: Dual-omics evidence for the beneficial effects of GSH [0.03%]
谷氨酰胺联合自体骨髓干细胞治疗兔膝骨关节炎的疗效及其对软骨下骨的影响
Tianhao Li,Xuefeng Bai,Yuejiao Liao et al.
Tianhao Li et al.
Early embryonic development depends on precise redox homeostasis and mitochondrial quality control; however, how AMPK regulates embryonic fate through mitophagy remains unclear. In this study, integrated transcriptomic and proteomic analyse...
Microbial signatures of the vaginal microbiome associated with pregnancy outcome in central Anatolian Merino sheep [0.03%]
与安纳托利亚美利奴羊妊娠结局相关的阴道微生物标志物
Necati Esener,Mesut Kırbaş,Yavuz Kal et al.
Necati Esener et al.
Reproductive efficiency is a key determinant of sustainability and profitability in sheep farming systems; however, the role of the vaginal microbiome in shaping pregnancy outcomes remains insufficiently understood. This study aimed to char...
Astaxanthin activates PI3K/AKT and AMPK signaling to alleviate oxidative stress and improve mouse oocyte In vitro maturation [0.03%]
虾青素通过激活PI3K/AKT和AMPK信号通路缓解氧化应激并改善体外培养小鼠卵母细胞成熟率
Mei Zhou,Mengzhen Luo,Yueming Yuan et al.
Mei Zhou et al.
Assisted reproductive technology (ART) has broad applications in livestock production, biomedical research, and developmental biology. Oocyte in vitro maturation (IVM) is a critical step in ART; however, oxidative stress-induced impairment ...
Aquaporins 1, 2, 4, and 9 in gander testes throughout the annual period [0.03%]
雄鹅全年睾丸中的水通道蛋白1、2、4和9
Małgorzata Gumułka,Anna Hrabia,Karolina Frydrych et al.
Małgorzata Gumułka et al.
Many efforts have been made to study the role of aquaporins (AQPs) in livestock reproduction, but little data are available on poultry. The aim of the study was to investigate the mRNA transcript levels, protein abundance, and immunofluores...